{"id":42977,"date":"2023-06-09T16:40:17","date_gmt":"2023-06-09T08:40:17","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=42977"},"modified":"2023-06-09T17:17:29","modified_gmt":"2023-06-09T09:17:29","slug":"cd22-%e9%87%8d%e7%b5%84%e8%9b%8b%e7%99%bd-t-b-cell-surface-proteins-bioworld%e8%b2%a8%e8%99%9fncp0191","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=42977","title":{"rendered":"CD22\u00a0 \u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP0191"},"content":{"rendered":"

CD22\u00a0 \u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP0191<\/span><\/strong><\/a><\/span><\/p>\n

CD22 Recombinant Protein<\/p>\n

DNAM-1\/CD226 \u662f\u514d\u75ab\u7403\u86cb\u767d\u6a23\u8d85\u5bb6\u65cf\u7684\u6210\u54e1( immunoglobulin-like superfamily)\u3002\u5b83\u5728 T \u7d30\u80de(T cells)\u3001\u81ea\u7136\u6bba\u50b7 ( natural killer, NK) \u7d30\u80de\u3001\u55ae\u6838\u7d30\u80de(monocytes)\u548c\u5de8\u566c\u7d30\u80de(macrophages)\u4e0a\u8868\u9054\u3002\u5b83\u662f NK \u7d30\u80de( NK cells)\u4e0a\u7684\u4e3b\u8981\u6fc0\u6d3b\u53d7\u9ad4( activating receptor )\u3002\u8207\u5176\u914d\u9ad4 Nectin-2 (CD112) \u548c PVR\u810a\u9ad3\u7070\u8cea\u708e\u75c5\u6bd2\u53d7\u9ad4(poliovirus receptor)\uff0c\u4e5f\u7a31\u70ba CD155\u3002\u5728\u9776\u7d30\u80de\u4e0a\u7684\u7d50\u5408\u5c0e\u81f4 ERK\u3001AKT \u548c PLCg2 \u4fe1\u865f\u901a\u8def\u7684\u4e0b\u6e38\u6fc0\u6d3b\uff0c\u9019\u5c0d\u65bc NK \u6fc0\u6d3b\u548c NK \u4ecb\u5c0e\u7684\u6bba\u50b7\u81f3\u95dc\u91cd\u8981\u3002 LFA-1 \u5728\u7269\u7406\u4e0a\u8207 DNAM-1\/CD226 \u76f8\u95dc\u806f\u4e26\u6709\u52a9\u65bc\u5176\u4fe1\u865f\u50b3\u5c0e\u3002 DNAM-1\/CD226 \u7684\u6fc0\u6d3b\u4fe1\u865f\u88ab\u6291\u5236\u6027\u53d7\u9ad4 TIGIT \u548c CD96 \u62b5\u6d88\uff0c\u7af6\u722d\u5171\u540c\u914d\u9ad4 CD122 \u548c PVR\u3002DNAM-1\/CD226 \u662f\u514d\u75ab\u7403\u86cb\u767d\u6a23\u8d85\u65cf\u7684\u6210\u54e1\u3002\u5b83\u5728 T \u7d30\u80de(T cells)\u3001\u81ea\u7136\u6bba\u50b7 ( natural killer, NK) \u7d30\u80de\u3001\u55ae\u6838\u7d30\u80de(monocytes)\u548c\u5de8\u566c\u7d30\u80de(macrophages)\u8868\u73fe\u51fa\u4f86\u3002\u5b83\u662fNK\u7d30\u7bc0\u4e0a\u7684\u4e3b\u8981\u523a\u6fc0\u6027\u53d7\u9ad4\u3002\u8207\u5176ligands Nectin-2 (CD112) \u548cPVR\uff08\u810a\u9ad3\u7070\u8cea\u708e\u75c5\u6bd2\u53d7\u9ad4\uff0c\u4e5f\u7a31CD155\uff09\u5728\u9aa8\u9abc\u4e0a\u7684\u7d50\u5408\u5c0e\u81f4ERK\u3001AKT\u548cPLCg2\u4fe1\u865f\u901a\u8def\u7684\u4e0b\u6e38\u6fc0\u60c5\uff0c\u9019\u5c0d\u65bcNK \u6fc0\u60c5\u548c NK \u4ecb\u7d39\u7684\u6bba\u50b7\u81f3\u95dc\u91cd\u8981\u3002 LFA-1 \u5728\u7269\u7406\u4e0a\u8207 DNAM-1\/CD226 \u76f8\u95dc\u806f\u4e26\u6709\u52a9\u65bc\u5176\u4fe1\u865f\u50b3\u5c0e\u3002 DNAM-1\/CD226 \u7684\u6d3b\u6027\u4fe1\u865f\u88ab\u6291\u5236\u6027\u53d7\u9ad4 TIGIT \u548c CD96 \u727d\u6d88\uff0c\u7af6\u8cfd\u5171\u914d\u9ad4CD122 \u548cPVR\u3002<\/p>\n

https:\/\/bioworlde.com\/<\/a><\/p>\n

<\/p>\n

 <\/p>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Product Name<\/td>\nCD22 Recombinant Protein<\/td>\n<\/tr>\n
Catalog No.<\/td>\nNCP0191<\/td>\n<\/tr>\n
Swiss-Prot<\/td>\nP20273<\/a><\/td>\n<\/tr>\n
Host<\/td>\nE.coli<\/td>\n<\/tr>\n
Tag<\/td>\nHis-tag in C-terminal<\/td>\n<\/tr>\n
Restriction sites<\/td>\nNdeI-XhoI<\/td>\n<\/tr>\n
Background<\/td>\n<\/td>\n<\/tr>\n
Soluble<\/td>\nPBS, 4M Urea, PH7.4<\/td>\n<\/tr>\n
Purification&Purity<\/td>\nTransferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).<\/td>\n<\/tr>\n
Concentration<\/td>\n\u22650.5mg\/ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

Product Name :<\/b>
\nCD22 Recombinant Protein<\/p>\n

Swiss-Prot :<\/b>
\nP20273<\/a><\/p>\n

Host :<\/b>
\nE.coli<\/p>\n

Tag :<\/b>
\n\u22650.5mg\/ml<\/p>\n

Soluble :<\/b>
\nPBS, 4M Urea, PH7.4<\/p>\n

Purification&Purity :<\/b>
\nTransferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).<\/p>\n

Storage&Stability :<\/b>
\nStore at 4\u00b0C short term. Aliquot and store at -20\u00b0C long term. Avoid freeze-thaw cycles.<\/p>\n

Expression vector :<\/b>
\npet-22b(+)<\/p>\n

BiowMW :<\/b>
\n~26kDa<\/p>\n

Note :<\/b>
\nFor research use only, not for use in diagnostic procedure.<\/p>\n

concentration :<\/b>
\n\u22650.5mg\/ml<\/p>\n","protected":false},"excerpt":{"rendered":"

CD22\u00a0 \u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP019 […]<\/p>\n","protected":false},"author":3,"featured_media":31670,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5799],"tags":[5825],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42977"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=42977"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42977\/revisions"}],"predecessor-version":[{"id":42978,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42977\/revisions\/42978"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/31670"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=42977"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=42977"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=42977"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}