{"id":37472,"date":"2023-01-11T16:01:09","date_gmt":"2023-01-11T08:01:09","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=37472"},"modified":"2023-01-16T11:44:53","modified_gmt":"2023-01-16T03:44:53","slug":"%e9%80%8f%e6%98%8e%e8%b3%aa%e9%85%b8%e9%85%b6hyaluronidase%e6%b4%bb%e6%80%a7%e8%a9%a6%e5%8a%91%e7%9b%92-hyaluronidase-activity-kits-amsbio%e8%b2%a8%e8%99%9fra002-02-k","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=37472","title":{"rendered":"\u900f\u660e\u8cea\u9178\u9176(Hyaluronidase)\u6d3b\u6027\u8a66\u5291\u76d2 | Hyaluronidase Activity Kits- Amsbio\u8ca8\u865fRa002-02-K"},"content":{"rendered":"<p><span style=\"color: #33cccc;\"><strong><span style=\"font-size: 12pt;\">\u3010\u4e59\u91af\u809d\u7d20\u9176(Heparanase)\u548c\u900f\u660e\u8cea\u9178\u9176(Hyaluronidase)\u6d3b\u6027\u8a66\u5291\u76d2\u3011Heparanase and\u00a0<em>Hyaluronidase<\/em>\u00a0Activity Kits- Amsbio<\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/01\/enzyme-acitivity-feature.jpg\" alt=\"\" \/><\/p>\n<p>AMSBIO \u63d0\u4f9b Razie \u6aa2\u6e2c\u8a66\u5291\u76d2\uff08\u4e59\u91af\u809d\u7d20\u9176\u3001\u900f\u660e\u8cea\u9178\u9176\u6d3b\u6027\u6aa2\u6e2c\u8a66\u5291\u76d2\uff09\uff0c\u7528\u65bc\u5206\u5225\u6e2c\u91cf\u7d30\u80de\u57f9\u990a\u4e0a\u6e05\u6db2(cell culture supernatants)\u3001\u4eba\u8840\u6f3f(human plasma)\u3001\u751f\u7269\u9ad4\u6db2(biological fluids)\u548c\u7d44\u7e54\u6a23\u672c(tissue samples)\u4e2d\u4e59\u91af\u809d\u7d20\u9176(heparinase)\u548c\u900f\u660e\u8cea\u9178\u9176(hyaluronidase)\u7684\u9176\u6d3b\u6027\u3002\u6211\u5011\u7684\u8a66\u5291\u76d2\u5df2\u7528\u65bc\u7814\u7a76\u6297\u708e\u53cd\u61c9(anti-inflammatory responses)\u3001\u814e\u81df\u75be\u75c5(kidney disease)\u548c\u764c\u75c7\u7814\u7a76(cancer research.)\u3002\u4e59\u91af\u809d\u7d20\u9176(Heparanase)\u548c\u900f\u660e\u8cea\u9178\u9176(hyaluranidase enzymes)\u5747\u5728\u7d30\u80de\u5916\u57fa\u8cea (extracellular matrix , ECM) \u4e2d\u767c\u63ee\u91cd\u8981\u4f5c\u7528\u3002Razie \u6aa2\u6e2c\u8a66\u5291\u76d2\u70ba\u9019\u4e9b\u985e\u578b\u9176\u7684\u50b3\u7d71\u6e2c\u91cf\u6280\u8853\u6240\u767c\u73fe\u7684\u6027\u80fd\u548c\u6a19\u6e96\u5316\u554f\u984c\u63d0\u4f9b\u77ad\u89e3\u6c7a\u65b9\u6848\u3002<\/p>\n<p><strong><span style=\"font-size: 12pt; color: #800000;\">Each assay is available in two formats:<\/span><\/strong><\/p>\n<ul>\n<li style=\"font-style: inherit; font-weight: inherit;\">with enzyme as positive control to demonstrate digestion\/activity.<\/li>\n<li style=\"font-style: inherit; font-weight: inherit;\">without positive control, for end-users who have their own enzyme for use as positive control.<\/li>\n<\/ul>\n<p><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\">Glycosaminoglycan Substrates<\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/01\/Glycosaminoglycan-Substrates.jpg\" alt=\"\" \/><\/p>\n<p><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\">Heparanase Assay Kit: \u8ca8\u865fRa001-PCE-K\/Ra001-NPCE-K<\/span><\/strong><\/span><\/p>\n<p>\u5df2\u77e5\u786b\u9178\u4e59\u91af\u809d\u7d20\u86cb\u767d\u591a\u91a3 (Heparan sulfate proteoglycans , HSPG) \u5728\u9023\u63a5\u57fa\u5e95\u819c(the basement membrane)\u7684\u7d44\u5206\u86cb\u767d(component proteins)\u3001\u63a7\u5236\u819c\u6ef2\u900f\u6027(membrane permeability)\u548c\u4fe1\u865f\u8f49\u5c0e(signal transduction)\u65b9\u9762\u767c\u63ee\u91cd\u8981\u7684\u7d50\u69cb\u548c\u529f\u80fd\u4f5c\u7528\u3002\u5f8c\u4e00\u7a2e\u529f\u80fd\u662f\u901a\u904e\u63a7\u5236\u7d30\u80de\u56e0\u5b50\u548c\u751f\u9577\u56e0\u5b50\u5c0d\u5176\u7d30\u80de\u53d7\u9ad4\u7684\u751f\u7269\u5229\u7528\u5ea6\u4f86\u5be6\u73fe\u7684\u3002\u7d30\u80de\u8868\u9762\u7684 HSPG \u901a\u904e\u4fc3\u9032\u751f\u9577\u56e0\u5b50(growth factors)\u8207\u5176\u53d7\u9ad4\u4e4b\u9593\u7684\u76f8\u4e92\u4f5c\u7528\u53c3\u8207\u4fe1\u865f\u8f49\u5c0e(signal transduction)\u3002\u4e59\u91af\u809d\u7d20\u9176(Heparanase)\u662f\u4e00\u7a2e\u5167\u5207\u7cd6\u82f7\u9176(endoglycosidase)\uff0c\u53ef\u7279\u7570\u6027\u5207\u5272 HSPG \u7684\u786b\u9178\u4e59\u91af\u809d\u7d20 (heparan sulfate ,HS) \u5074\u93c8\u3002<\/p>\n<p><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\">Heparanase assay workflow<\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/01\/heparanase-workflow.jpg\" alt=\"\" \/><\/p>\n<table>\n<thead>\n<tr>\n<th>Name<\/th>\n<th>Datasheet<\/th>\n<th>Packsize<\/th>\n<th class=\"action_column\">Order<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Heparanase Assay Kit with Positive Control Enzyme<\/td>\n<td><a href=\"https:\/\/resources.amsbio.com\/Datasheets\/Ra001-PCE-K.pdf\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.amsbio.com\/wp\/wp-content\/uploads\/2019\/07\/icon-pdf.jpg\" alt=\"\" \/><\/a><\/td>\n<td>1<\/td>\n<td><a class=\"button button_size_2 button_js\" href=\"https:\/\/www.amsbio.com\/heparanase-assay-kit-with-positive-control-enzyme\">View<\/a><\/td>\n<\/tr>\n<tr>\n<td>Heparanase Assay Kit without Positive Control Enzyme<\/td>\n<td><a href=\"https:\/\/resources.amsbio.com\/Datasheets\/Ra001-NPCE-K.pdf\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.amsbio.com\/wp\/wp-content\/uploads\/2019\/07\/icon-pdf.jpg\" alt=\"\" \/><\/a><\/td>\n<td>1<\/td>\n<td><a class=\"button button_size_2 button_js\" href=\"https:\/\/www.amsbio.com\/heparanase-assay-kit-without-positive-control-enzyme\">View<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong><span style=\"font-size: 12pt; color: #800000;\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E5%AF%A6%E9%A9%97%E8%A8%AD%E5%82%991-300x288.png\" alt=\"ELISA reader\" width=\"254\" height=\"207\" \/><\/span><\/strong><\/p>\n<p><strong><span style=\"font-size: 12pt; color: #800000;\">Hyaluronidase Assay Kit: \u8ca8\u865fRa003-01-HAK\/Ra002-02-K<\/span><\/strong><\/p>\n<p style=\"font-style: inherit; font-weight: inherit;\">\u900f\u660e\u8cea\u9178(Hyaluronic Acid)\u662f\u7d30\u80de\u5916\u57fa\u8cea\u4e2d\u91cd\u8981\u7684\u7d50\u69cb\u5927\u5206\u5b50(macromolecule)\uff0c\u53c3\u8207\u57fa\u8cea\u6210\u5206(matrix components)\u7684\u76f8\u4e92\u4f5c\u7528(interaction)\u3002\u54fa\u4e73\u52d5\u7269\u900f\u660e\u8cea\u9178\u9176\uff08Mammalian hyaluronidases , HYAL1 \u81f3 HYAL4\uff09\u662f\u901a\u904e\u6c34\u89e3 N-\u4e59\u91af\u6c28\u57fa\u8461\u8404\u7cd6(N-acetyl glucosamine)\u548c D-\u8461\u8404\u91a3\u919b\u9178(D-glucuronic)\u4e4b\u9593\u7684 1-4 \u9375\u4f86\u964d\u89e3\u900f\u660e\u8cea\u9178(hyaluronic acid)\u7684 ECM \u9176\u3002\u54fa\u4e73\u52d5\u7269\u900f\u660e\u8cea\u9178\u9176(hyaluronidases)\u4e5f\u53ef\u4ee5\u5207\u5272\u985e\u4f3c\u7684\u7cd6\u80fa\u805a\u91a3(glycosaminoglycans)\u3002Razie \u54fa\u4e73\u52d5\u7269\u900f\u660e\u8cea\u9178\u9176\u6aa2\u6e2c\u8a66\u5291\u76d2(Razie mammalian hyaluronidase assay kits)\u53ef\u7528\u65bc\u7be9\u9078\u900f\u660e\u8cea\u9178\u9176\u6291\u5236\u5291(hyaluronidase inhibitors)\u548c\u5b9a\u91cf\u900f\u660e\u8cea\u9178\u9176\u6d3b\u6027(hyaluronidase activity)\u3002\u8a72\u8a66\u5291\u76d2\u7684\u539f\u7406\u8207\u4e59\u91af\u809d\u7d20\u9176\u6aa2\u6e2c\u8a66\u5291\u76d2(heparanase assay kit)\u975e\u5e38\u76f8\u4f3c\u3002\u9069\u61c9\u6027\u53ef\u7528\u65bc\u6e2c\u91cf\u7d30\u83cc(bacterial )\u900f\u660e\u8cea\u9178\u9176 (hyaluronidase enzymes)\u7684\u6d3b\u6027\u3002<\/p>\n<p style=\"font-style: inherit; font-weight: inherit;\"><img decoding=\"async\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/01\/Mechanisms-and-significance-of-HA-degradation-by-mammalian-Hyaluronidase-Enzymes.jpg\" alt=\"\" \/><\/p>\n<table>\n<thead>\n<tr>\n<th>Name<\/th>\n<th>Datasheet<\/th>\n<th>Packsize<\/th>\n<th class=\"action_column\">Order<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Hyaluronidase Assay Kit<\/td>\n<td><a href=\"https:\/\/resources.amsbio.com\/Datasheets\/Ra003-01-HAK.pdf\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.amsbio.com\/wp\/wp-content\/uploads\/2019\/07\/icon-pdf.jpg\" alt=\"\" \/><\/a><\/td>\n<td>1<\/td>\n<td><a class=\"button button_size_2 button_js\" href=\"https:\/\/www.amsbio.com\/hyaluronidase-assay-kit-with-positive-control-enzyme-ra003-01-hak\">View<\/a><\/td>\n<\/tr>\n<tr>\n<td>Hyaluronidase Assay Kit without Positive control enzyme<\/td>\n<td><a href=\"https:\/\/resources.amsbio.com\/Datasheets\/Ra002-02-K.pdf\" target=\"_blank\"><img decoding=\"async\" src=\"https:\/\/www.amsbio.com\/wp\/wp-content\/uploads\/2019\/07\/icon-pdf.jpg\" alt=\"\" \/><\/a><\/td>\n<td>1<\/td>\n<td><a class=\"button button_size_2 button_js\" href=\"https:\/\/www.amsbio.com\/hyaluronidase-assay-kit-without-positive-control-enzyme\">View<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96-%E5%93%81%E7%89%8C%E4%BB%8B%E7%B4%B9_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1-300x120.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716 \u54c1\u724c\u4ecb\u7d39_\u5de5\u4f5c\u5340\u57df 1\" width=\"146\" height=\"60\" \/>\u00a0<span style=\"color: #008080;\"><strong><span style=\"font-size: 12pt;\"><a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?news=amsbio%e5%8f%b0%e7%81%a3%e4%bb%a3%e7%90%86%e5%95%86-brandagency%e4%bb%a3%e7%90%86%e5%93%81%e7%89%8c-amsbio\">Amsbio\u53f0\u7063\u4ee3\u7406\u5546-BRAND\/AGENCY\/\u4ee3\u7406\u54c1\u724c- Amsbio<\/a><\/span><\/strong><\/span><\/p>\n<p>AMSBIO\u65bc\u57fa\u56e0\u9ad4\u5b78\u3001\u86cb\u767d\u8cea\u9ad4\u5b78\u3001\u7d30\u80de\u57f9\u990a\u548c\u5e79\u7d30\u80de\u7b49\u9818\u57df\u5747\u6709\u6d89\u7565\u3002 \u9664\u4e86\u91dd\u5c0d\u7d30\u80de\u589e\u6b96\u3001\u8cbc\u9644\u3001\u8f49\u79fb\u548c\u4fb5\u5165\u7b49\u7814\u7a76\u7d30\u80de\u57fa\u790e\u529f\u80fd\u4e4b\u7522\u54c1\uff0c\u53e6\u5916\u9084\u63d0\u4f9b\u6b63\u5e38\u4eba\u53ca\u75be\u75c5\u60a3\u8005\u7684\u751f\u7269\u6027\u6a23\u672c\uff0c\u4f8b\u5982\u4e73\u764c\u3001\u7d50\u8178\u764c\u7b49\uff0c\u4ee5\u7b26\u5408\u7814\u7a76\u8005\u7684\u9700\u6c42\u3002\u7522\u54c1\u7dda\u5305\u542bDNA\/RNA\/\u86cb\u767d\u8cea\/\u7d44\u7e54\u5207\u7247\u6a23\u672c\u30013D\u7d30\u80de\u57f9\u990a\u3001\u6297\u9ad4\u53ca\u5404\u5f0f\u5206\u6790\u8a66\u5291\u76d2\u7b49\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u4e59\u91af\u809d\u7d20\u9176(Heparanase)\u548c\u900f\u660e\u8cea\u9178\u9176(Hyaluronidase)\u6d3b\u6027\u8a66\u5291\u76d2\u3011Heparanase [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":37460,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[5130],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37472"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37472"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37472\/revisions"}],"predecessor-version":[{"id":37481,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37472\/revisions\/37481"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/37460"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37472"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37472"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37472"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}