{"id":37007,"date":"2022-12-09T14:27:46","date_gmt":"2022-12-09T06:27:46","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=37007"},"modified":"2022-12-27T10:50:13","modified_gmt":"2022-12-27T02:50:13","slug":"mouse-anti-human-igg4-fc-unlb-hp6025-%e8%b2%a8%e8%99%9f9200-01","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=37007","title":{"rendered":"Mouse Anti-Human IgG4 Fc-UNLB (HP6025) | \u8ca8\u865f9200-01"},"content":{"rendered":"

Mouse Anti-Human IgG4 Fc-UNLB (HP6025)<\/strong> | <\/strong>\u8ca8\u865f<\/strong>9200-01<\/strong>\u00a0 <\/strong><\/span><\/a><\/span><\/p>\n

Purified Anti-Human IgG4 Fc antibody for use in ELISA, flow cytometry, immunohistochemistry \/ immunocytochemistry, western blot, microarray, purification, and multiplex assays.<\/p>\n

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\u7d30\u80de\u514d\u75ab\u5c08\u5bb6\u6975\u529b\u63a8\u85a6SouthernBiotech\u9ad8\u54c1\u8cea\u4e8c\u7d1a\u6297\u9ad4<\/p>\n

\u7f8e\u570b\u6297\u9ad4\u751f\u7522\u5546Southern Biotech\u65bc1982\u5e74\uff0c\u7531UAB\u7d30\u80de\u514d\u75ab\u5c08\u5bb6Dr. Max Cooper\u8207\u5be6\u9a57\u5ba4\u6210\u54e1\u5171\u540c\u5275\u7acb\u3002SouthernBiotech\u81f4\u529b\u65bc\u751f\u7522\u9ad8\u54c1\u8cea\u4e8c\u7d1a\u6297\u9ad4\u3002\u7269\u7a2e\u7a2e\u985e\u9f4a\u5168\uff0c\u5305\u62ec\u6709Bovine\u3001Canine\u3001Chicken\u3001Cynomolgus\u3001Donkey\u3001Equine\u3001Feline\u3001Goat\u3001Guinea Pig\u3001Hamster\u3001Human\u3001Monkey\u3001Mouse\u3001Porcine\u3001Rabbit\u3001Rat\u3001Rhesus\u3001Sheep\u3001Turkey\u3002\u5177\u6709\u87a2\u5149\u7269\u8cea\uff08FITC\u3001PE\u3001APC\u3001SPRD\u3001PE\/CY5.5\u3001APC\/CY5.5\u3001Spectral Red\u3001Alexa 488\u3001Alexa 647\u3001Pacific Blue\uff09\u5404\u7a2e\u87a2\u5149\u6a19\u8a8c\u3001\u53e6\u5177\u9175\u7d20\uff08HRP\u3001AP\uff09\u3001\u6216\u672a\u6a19\u8a8c\u53caLow Endotoxin\/Azide Free\uff08LE\/AF\uff09\u7b49\u6a19\u5b9a\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Clone<\/strong><\/td>\nHP6025<\/td>\n<\/tr>\n
Isotype<\/strong><\/td>\nMouse (BALB\/c) IgG1<\/sub>\u03ba<\/td>\n<\/tr>\n
Isotype Control<\/strong><\/td>\nMouse IgG1-UNLB (15H6)<\/a><\/td>\n<\/tr>\n
Specificity<\/strong><\/td>\nHuman IgG4<\/sub>\u00a0Fc<\/td>\n<\/tr>\n
Immunogen<\/strong><\/td>\nHuman IgG4<\/sub>\u00a0myeloma protein<\/td>\n<\/tr>\n
Conjugate<\/strong><\/td>\nUNLB (Unconjugated)<\/td>\n<\/tr>\n
Buffer Formulation<\/strong><\/td>\nBorate buffered saline, pH 8.2<\/td>\n<\/tr>\n
Clonality<\/strong><\/td>\nMonoclonal<\/td>\n<\/tr>\n
Concentration<\/strong><\/td>\n0.5 mg\/mL<\/td>\n<\/tr>\n
Volume<\/strong><\/td>\n1.0 mL<\/td>\n<\/tr>\n
Recommended Storage<\/strong><\/td>\n2-8\u00b0C<\/td>\n<\/tr>\n
Applications<\/strong><\/td>\nELISA \u2013 Quality tested\u00a02-9<\/sup>
\nFLISA \u2013 Quality tested
\nFlow Cytometry \u2013 Reported in literature\u00a015,18,19<\/sup>
\nImmunohistochemistry-Frozen Sections \u2013 Reported in literature\u00a010<\/sup>
\nImmunohistochemistry-Paraffin Sections \u2013 Reported in literature\u00a05,7,10,11<\/sup>
\nImmunocytochemistry \u2013 Reported in literature\u00a012<\/sup>
\nWestern Blot \u2013 Reported in literature\u00a03,13-16<\/sup>
\nMicroarray \u2013 Reported in literature\u00a017<\/sup>
\nMultiplex \u2013 Reported in literature\u00a02,20-22<\/sup>
\nPurification \u2013 Reported in literature\u00a015<\/sup><\/td>\n<\/tr>\n
RRID Number<\/strong><\/td>\nAB_2796689<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n3503<\/a>\u00a0(Human)<\/td>\n<\/tr>\n
Gene ID Symbol<\/strong><\/td>\nIGHG4<\/a>\u00a0(Human)<\/td>\n<\/tr>\n
UniProt ID<\/strong><\/td>\nP01861<\/a>\u00a0(Human)<\/td>\n<\/tr>\n
UniProt Name<\/strong><\/td>\nIGHG4_HUMAN<\/a>\u00a0(Human)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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    \n
  1. Reimer CB, Phillips DJ, Aloisio CH, Moore DD, Galland GG, Wells TW, et al. Evaluation of thirty-one mouse monoclonal antibodies to human IgG epitopes. Hybridoma. 1984;3:263-75. (Immunogen)<\/li>\n
  2. Arnold M, Dechant M, Doxiadis II, Spriewald BM. Prevalence and specificity of immunoglobulin G and immunoglobulin A non-complement-binding anti-HLA alloantibodies in retransplant candidates. Tissue Antigens. 2008;72:60-6. (ELISA, Multiplex)<\/li>\n
  3. Bogdanos D, Pusl T, Rust C, Vergani D, Beuers U. Primary biliary cirrhosis following Lactobacillus vaccination for recurrent vaginitis. J Hepatol. 2008;49:466-73. (ELISA, WB)<\/li>\n
  4. Forthal DN, Landucci G, Ding H, Kappes JC, Wang A, Thung I, et al. IgG2 inhibits HIV-1 internalization by monocytes, and IgG subclass binding is affected by gp120 glycosylation. AIDS. 2011;25:2099-104. (ELISA)<\/li>\n
  5. Jia X, Hu S, Chen J, Qu Z, Liu G, Cui Z, et al. The clinical and immunological features of patients with combined anti-glomerular basement membrane disease and membranous nephropathy. Kidney Int. 2014;85:945-52. (ELISA, IHC-PS)<\/li>\n
  6. Xu J, Wang L, Deng C, Hu X, Li R, Chen T, et al. The serological diagnosis of human clonorchiasis by time-resolved fluoroimmunoassay based on GST2-specific IgG4 detection. Parasitol Res. 2014;113:149-55. (ELISA)<\/li>\n
  7. Zhang J, Zhao L, Gao Y, Liu M, Li T, Huang Y, et al. A classification of Hashimoto’s thyroiditis based on immunohistochemistry for IgG4 and IgG. Thyroid. 2014;24:364-70. (ELISA, IHC-PS)<\/li>\n
  8. Westra J, van Assen S, Wilting KR, Land J, Horst G, de Haan A, et al. Rituximab impairs immunoglobulin (Ig)M and IgG (subclass) responses after influenza vaccination in rheumatoid arthritis patients. Clin Exp Immunol. 2014;178:40-7. (ELISA)<\/li>\n
  9. Seitz-Polski B, Payr\u00e9 C, Ambrosetti D, Albano L, Cassuto-Viguier E, Berguignat M, et al. Prediction of membranous nephropathy recurrence after transplantation by monitoring of anti-PLA2R1 (M-type phospholipase A2 receptor) autoantibodies: a case series of 15 patients. Nephrol Dial Transplant. 2014;29:2334-42. (ELISA)<\/li>\n
  10. Detlefsen S, Br\u00e4sen JH, Zamboni G, Capelli P, Kl\u00f6ppel G. Deposition of complement C3c, immunoglobulin (Ig)G4 and IgG at the basement membrane of pancreatic ducts and acini in autoimmune pancreatitis. Histopathology. 2010;57:825-35. (IHC-FS, IHC-PS)<\/li>\n
  11. Qu Z, Liu G, Li J, Wu L, Tan Y, Zheng X, et al. Absence of glomerular IgG4 deposition in patients with membranous nephropathy may indicate malignancy. Nephrol Dial Transplant. 2012;27:1931-7. (IHC-PS)<\/li>\n
  12. de Bruin A, Caldelari R, Williamson L, Suter MM, Hunziker T, Wyder M, et al. Plakoglobin-dependent disruption of the desmosomal plaque in pemphigus vulgaris. Exp Dermatol. 2007;16:468-75. (ICC)<\/li>\n
  13. M\u00fcller E, Kernland K, Caldelari R, Wyder M, Balmer V, Hunziker T, et al. Unusual pemphigus phenotype in the presence of a Dsg1 and Dsg3 autoantibody profile. J Invest Dermatol. 2002;118:551-5. (WB)<\/li>\n
  14. Bogdanos D, Pares A, Baum H, Caballeria L, Rigopoulou EI, Ma Y, et al. Disease-specific cross-reactivity between mimicking peptides of heat shock protein of Mycobacterium gordonae and dominant epitope of E2 subunit of pyruvate dehydrogenase is common in Spanish but not British patients with primary biliary cirrhosis. J Autoimmun. 2004;22:353-62. (WB)<\/li>\n
  15. Keen J, Serghides L, Ayi K, Patel SN, Ayisi J, van Eijk A, et al. HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites. PLoS Med. 2007;4(5):e181. (WB, FC, Purificaton)<\/li>\n
  16. Parcina M, Miranda-Garcia MA, Durlanik S, Ziegler S, Over B, Georg P, et al. Pathogen-triggered activation of plasmacytoid dendritic cells induces IL-10-producing B cells in response to Staphylococcus aureus. J Immunol. 2013;190:1591-602. (WB)<\/li>\n
  17. Savilahti EM, Rantanen V, Lin JS, Karinen S, Saarinen KM, Goldis M, et al. Early recovery from cow’s milk allergy is associated with decreasing IgE and increasing IgG4 binding to cow’s milk epitopes. J Allergy Clin Immunol. 2010;125:1315-21. (Microarray)<\/li>\n
  18. Johansson SE, Hejdeman B, Hinkula J, Johansson MH, Romagn\u00e9 F, Wahren B, et al. NK cell activation by KIR-binding antibody 1-7F9 and response to HIV-infected autologous cells in viremic and controller HIV-infected patients. Clin Immunol. 2010;134:158-68. (FC)<\/li>\n
  19. Gao B, Moore C, Porcheray F, Rong C, Abidoglu C, DeVito J, et al. Pretransplant IgG reactivity to apoptotic cells correlates with late kidney allograft loss. Am J Transplant. 2014;14:1581-91. (FC)<\/li>\n
  20. Lowe D, Higgins R, Zehnder D, Briggs DC. Significant IgG subclass heterogeneity in HLA-specific antibodies: Implications for pathogenicity, prognosis, and the rejection response. Hum Immunol. 2013;74:666-72. (Multiplex)<\/li>\n
  21. Arnold M, Ntokou I, Doxiadis II, Spriewald BM, Boletis JN, Iniotaki AG. Donor-specific HLA antibodies: evaluating the risk for graft loss in renal transplant recipients with isotype switch from complement fixing IgG1\/IgG3 to noncomplement fixing IgG2\/IgG4 anti-HLA alloantibodies. Transpl Int. 2014;27:253-61. (Multiplex)<\/li>\n
  22. Schaub S, H\u00f6nger G, Koller MT, Liwski R, Amico P. Determinants of C1q binding in the single antigen bead assay. Transplantation. 2014;98:387-93. (Multiplex)<\/li>\n<\/ol>\n

     <\/p>\n

    Isotype control \u5206\u578b\u5c0d\u7167\u7d44<\/a> | \u5206\u578b\u5c0d\u7167\u7d44\u5957\u7d44<\/a> | \u6297\u9ad4\u5206\u578bELISA \u5957\u7d44<\/a> | anti-rabbit \u4e8c\u7d1a\u6297\u9ad4<\/a> | anti-mouse\u4e8c\u7d1a\u6297\u9ad4<\/a> |<\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Mouse Anti-Human IgG4 Fc-UNLB (HP6025) | \u8ca8\u865f9200-01\u00a0 Pur […]<\/p>\n","protected":false},"author":3,"featured_media":37008,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[198],"tags":[5090],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37007"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=37007"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37007\/revisions"}],"predecessor-version":[{"id":37014,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/37007\/revisions\/37014"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/37008"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=37007"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=37007"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=37007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}