{"id":34625,"date":"2022-10-11T20:43:06","date_gmt":"2022-10-11T12:43:06","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=34625"},"modified":"2025-11-15T15:26:18","modified_gmt":"2025-11-15T07:26:18","slug":"nystatin-fungicidin-cas1400-61-9-apexbio%e8%b2%a8%e8%99%9fb1993","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=34625","title":{"rendered":"Nystatin (Fungicidin) | CAS#1400-61-9 APExBIO\u8ca8\u865fB1993"},"content":{"rendered":"

\u6297\u751f\u7d20\u5316\u5408\u7269\u7cfb\u5217\u5546\u54c1->>Nystatin (Fungicidin)<\/span><\/span><\/span><\/span><\/strong><\/p>\n

APExBIO Technology LLC \u662f\u4e00\u5bb6\u9818\u5148\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5291 (Small Molecule Inhibitors)\/\u6d3b\u5316\u5291(Activators)\u3001\u5316\u5408\u7269\u5eab( Compound Libraries)\u3001\u80dc\u80bd(Peptides)\u3001\u6aa2\u6e2c\u8a66\u5291\u76d2(Assay Kits)\u3001\u87a2\u5149\u6a19\u8a18(Fluorescent Label)\u3001\u9176(Enzymes)\u3001\u4fee\u98fe\u6838\u82f7\u9178(Modified Nucleotides)\u3001mRNA \u5408\u6210\u4ee5\u53ca\u5404\u7a2e\u5206\u5b50\u751f\u7269\u5b78\u5de5\u5177\u7684\u4f9b\u61c9\u5546\u3002APExBIO\u63d0\u4f9b\u5ee3\u6cdb\u7684\u7522\u54c1\u7dda\uff0c\u6db5\u84cb 20 \u591a\u500b\u4e0d\u540c\u7684\u7814\u7a76\u9818\u57df\uff0c\u4f8b\u5982\u764c\u75c7(cancer)\u3001\u514d\u75ab\u5b78(immunology)\u3001\u795e\u7d93\u79d1\u5b78(neurosciences)\u3001\u7d30\u80de\u51cb\u4ea1(apoptosis)\u548c\u8868\u89c0\u907a\u50b3\u5b78(epigenetics)\u7b49\u3002\u516c\u53f8\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u5fb7\u5dde\u4f11\u58eb\u9813USA (Houston, Texas)\uff0c\u81f4\u529b\u65bc\u670d\u52d9\u5168\u7403\u5ba2\u6236\u3002\u9ad8\u5ea6\u91cd\u8996\u7522\u54c1\u54c1\u8cea\u3002\u6240\u6709\u7522\u54c1\u5747\u9075\u5faa\u56b4\u683c\u7684\u751f\u7522\u6307\u5357\uff0c\u4e26\u9644\u6709\u5206\u6790\u8b49\u66f8\u3001HPLC\u3001\u8cea\u8b5c(Mass Spectrum)\u548cHMNR\u4ee5\u53ca\u9ad4\u5916\u9a57\u8b49(in vitro validation)\u3002 APExBIO\u7522\u54c1\u5df2\u88ab\u300aNature\u300b\u3001\u300aCell\u300b\u548c\u300aScience\u300b\u7b49\u773e\u591a\u9802\u7d1a\u540c\u884c\u8a55\u5be9\u671f\u520a\u5f15\u7528\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

<\/p>\n

Nystatin (Fungicidin) | CAS#1400-61-9 APExBIO\u8ca8\u865fB1993<\/a><\/span><\/p>\n

antifungal antibiotic<\/p>\n

\"Nystatin<\/p>\n

\u5236\u9ef4\u83cc\u7d20\uff08Fungicidin\uff09\u662f\u4e00\u7a2e\u591a\u70ef\u985e\u6297\u771f\u83cc\u6297\u751f\u7d20(polyene antifungal antibiotic[ 1]\u3002\u6297\u771f\u83cc\u6297\u751f\u7d20(Antifungal antibiotic)\u662f\u4e00\u7a2e\u7528\u65bc\u6cbb\u7642\u548c\u9810\u9632\u771f\u83cc\u75c5\u7684\u85e5\u7269\u6bba\u83cc\u5291\u3002\u5236\u9ef4\u83cc\u7d20\u662f\u4e00\u7a2e\u591a\u70ef\u985e\u6297\u771f\u83cc\u6297\u751f\u7d20(polyene antifungal antibiotic\uff0c) \u5c0d\u9175\u6bcd\u83cc\u548c\u652f\u539f\u9ad4(mycoplasma)\u6709\u6548[1]\u3002 \u5728\u6db2\u9ad4\u57f9\u990a\u57fa\u4e2d\uff0c\u5236\u9ef4\u83cc\u7d20\u4ee5 5-20 U\/ml [2] \u7684\u6fc3\u5ea6\u6291\u5236\u767d\u8272\u5ff5\u73e0\u83cc(C. albicans)\u3002\u5728200\u500b\u81e8\u5e8a\u5206\u96e2\u682a\u4e2d\uff0c\u5305\u62ec113\u500b\u767d\u8272\u5ff5\u73e0\u83cc(Candida albicans)\u300154\u500b\u5149\u6ed1\u5ff5\u73e0\u83cc(Candida glabrata)\u300111\u500b\u8fd1\u5e73\u6ed1\u5ff5\u73e0\u83cc(Candida parapsilosis)\u300111\u500b\u71b1\u5e36\u5ff5\u73e0\u83cc(Candida tropicalis)\u548c11\u500b\u514b\u6c0f\u5ff5\u73e0\u83cc(Candida krusei)\u3002 \u5236\u9ef4\u83cc\u7d20\u5c0d\u767d\u8272\u5ff5\u73e0\u83cc\u5206\u96e2\u682a\u548c\u6240\u6709\u6e2c\u8a66\u7684\u975e\u767d\u8272\u5ff5\u73e0\u83cc\u7684 MIC90 \u503c\u70ba 4 mg\/L\u3002 \u7d50\u679c\u8b49\u5be6\uff0c\u767d\u8272\u5ff5\u73e0\u83cc\u6700\u5e38\u6613\u611f\uff0c\u5236\u9ef4\u83cc\u7d20\uff08Fungicidin\uff09\u53ef\u7528\u65bc\u6cbb\u7642\u7531\u975e\u767d\u8272\u5ff5\u73e0\u83cc\u5f15\u8d77\u7684\u5916\u9670\u9670\u9053\u5ff5\u73e0\u83cc\u75c5\u3002\u5236\u9ef4\u83cc\u7d20\uff08Fungicidin\uff09\u5c07\u662f\u53d7\u975e\u767d\u8272\u5ff5\u73e0\u83cc\u611f\u67d3\u7684\u5973\u6027\u7684\u91cd\u8981\u9078\u64c7\uff0c\u9019\u4e9b\u5ff5\u73e0\u83cc\u5c0d\u57fa\u65bc\u54aa\u5511(imidazole-based)\u7684\u6cbb\u7642\u5177\u6709\u66f4\u9ad8\u7684\u6297\u6027 [3]\u3002<\/p>\n

    \n
  1. Wei P, Ning M, et al. “Spiroplasma eriocheiris entered Drosophila Schneider 2 cells and relied on clathrin-mediated endocytosis and macropinocytosis.” Infect Immun. 2019 Aug 26. pii: IAI.00233-19.PMID:31451616<\/a><\/li>\n
  2. Wang H, Liu W, et al. “Inhibitor analysis revealed that clathrin-mediated endocytosis is involed in cellular entry of type III grass carp reovirus.” Virol J. 2018 May 24;15(1):92.PMID:29793525<\/a><\/li>\n<\/ol>\n

    \"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    Physical Appearance<\/td>\nA solid<\/td>\n<\/tr>\n
    Storage<\/td>\nStore at -20\u00b0C<\/td>\n<\/tr>\n
    M.Wt<\/td>\n926.09<\/td>\n<\/tr>\n
    Cas No.<\/td>\n1400-61-9<\/td>\n<\/tr>\n
    Formula<\/td>\nC47H75NO17<\/td>\n<\/tr>\n
    Solubility<\/td>\n\u226530.45 mg\/mL in DMSO; insoluble in EtOH; insoluble in H2O<\/td>\n<\/tr>\n
    Chemical Name<\/td>\n(4E,6E,8E,10E,14E,16E,18S,19R,20R,21S,35S)-3-[(2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid<\/td>\n<\/tr>\n
    SDF<\/td>\nDownload SDF<\/a><\/td>\n<\/tr>\n
    Canonical SMILES<\/td>\nCC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O<\/td>\n<\/tr>\n
    Shipping Condition<\/td>\nShip with blue ice, or upon other requests.<\/td>\n<\/tr>\n
    General tips<\/td>\nFor obtaining a higher solubility, please warm the tube at 37\u00b0C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/p>\n

    \"\u76d2\u5b50\u6a23\u54c12\"<\/p>\n

    APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n

    https:\/\/www.apexbt.com\/<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    APExBIO\u7522\u54c1\u7dda<\/td>\n\u54c1\u9805<\/td>\nCAS#<\/td>\n#\u8ca8\u865f<\/td>\n<\/tr>\n
    Proteases<\/td>\nZ-VAD-FMK | CAS# 187389-52-2 APExBIO\u00a0 <\/a><\/td>\nCAS# 187389-52-2<\/td>\n\u8ca8\u865f\u00a0A1902<\/td>\n<\/tr>\n
    Proteinase K<\/td>\n\u86cb\u767d\u9176 K (Proteinase K) | CAS#39450-01-6 APExBIO\u00a0 \u8ca8\u865fK1037<\/a><\/td>\nCAS#39450-01-6<\/td>\n\u8ca8\u865fK1037<\/td>\n<\/tr>\n
    \u54c1\u9805<\/td>\nCAS#<\/td>\n#\u8ca8\u865f<\/td>\n\u61c9\u7528<\/td>\n<\/tr>\n
    Romidepsin (FK228, depsipeptide)<\/a><\/td>\n\n

    CAS#128517-07-7<\/p>\n

     <\/td>\n

    		\u8ca8\u865fA8173<\/td>\nHDAC1\/HDAC2\uff0c\u5f37\u6548\u548c\u9078\u64c7\u6027\u6291\u5236\u5291<\/td>\n<\/tr>\n
    Pirarubicin<\/a><\/td>\nCAS#72496-41-4<\/td>\n\u8ca8\u865fB2295<\/td>\n\u00a0anthracycline anti-neoplastic doxorubicin<\/td>\n<\/tr>\n
    Tunicamycin<\/a><\/td>\nCAS# 15663-27-1<\/td>\n\n

    \u8ca8\u865fA8321<\/p>\n

     <\/td>\n

    		\u9ad8\u6548\u3001\u5ee3\u8b5c\u7684\u5316\u7642\u85e5\u7269<\/td>\n<\/tr>\n
    Azithromycin<\/a><\/td>\nCAS#83905-01-5<\/td>\n\u00a0\u8ca8\u865fA2213<\/td>\nHsp90 inhibitor<\/td>\n<\/tr>\n
    Bleomycin Sulfate<\/a><\/td>\n\n

    CAS# 9041-93-4<\/p>\n

     <\/td>\n

    		\u8ca8\u865fB1398<\/td>\nAntibiotic by inhibiting protein synthesis<\/td>\n<\/tr>\n
    Nystatin (Fungicidin)<\/a><\/td>\nCAS#1400-61-9<\/td>\n\u8ca8\u865fB1993<\/td>\nantifungal antibiotic<\/td>\n<\/tr>\n
    Rapamycin<\/a><\/td>\nCAS#53123-88-9<\/td>\n\u8ca8\u865fA8167<\/td>\nOriginal antifungal antibiotic<\/td>\n<\/tr>\n
    Daptomycin<\/a><\/td>\nCAS#103060-53-3<\/td>\n\u8ca8\u865fA1206<\/td>\nCalcium-dependent antibiotic<\/td>\n<\/tr>\n
    \u54c1\u9805<\/td>\nCAS#<\/td>\n#\u8ca8\u865f<\/td>\n\u61c9\u7528<\/td>\n<\/tr>\n
    Z-VAD-FMK \u00a0<\/a><\/td>\nCAS# 187389-52-2<\/td>\n\u8ca8\u865f\u00a0A1902<\/td>\n\n

    Proteases<\/p>\n

    ICE-like proteases<\/td>\n<\/tr>\n

    TAPI-1 \u00a0<\/a><\/td>\nCAS#171235-71-5<\/td>\n\u8ca8\u865f\u00a0B4686<\/td>\n\n

    Proteases<\/p>\n

    TACE\/ADAM17 inhibitor Product Citation+3<\/td>\n<\/tr>\n

    Talabostat mesylate<\/a><\/td>\nCAS# 150080-09-4<\/td>\n\u8ca8\u865fB3941<\/td>\n\n

    Proteases<\/p>\n

    DPP4 \u4e8c\u80bd\u57fa\u80bd\u9176\u7279\u7570\u6027\u6291\u5236\u5291<\/td>\n<\/tr>\n

    Z-IETD-FMK<\/a><\/td>\nCAS# 210344-98-2<\/td>\n\u8ca8\u865fB3232<\/td>\ninhibitor of caspase 8<\/td>\n<\/tr>\n
    Cisplatin<\/td>\nCAS# 15663-27-1<\/td>\n\u8ca8\u865fA8321<\/td>\n\u9ad8\u6548\u3001\u5ee3\u8b5c\u7684\u5316\u7642\u85e5\u7269<\/td>\n<\/tr>\n
    17-DMAG (Alvespimycin) HCl<\/a><\/td>\nCAS#467214-21-7<\/td>\n\u00a0\u8ca8\u865fA2213<\/td>\nHsp90 inhibitor<\/td>\n<\/tr>\n
    CA-074 Me\u00a0<\/a><\/td>\nCAS# 147859-80-1<\/td>\n\u8ca8\u865fA8239<\/td>\nCathepsin B inhibitor<\/td>\n<\/tr>\n
    VX-765<\/a><\/td>\nCAS# 273404-37-8<\/td>\n\u8ca8\u865fA8238<\/td>\nCaspase-1 inhibitor<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    \u6297\u751f\u7d20\u5316\u5408\u7269\u7cfb\u5217\u5546\u54c1->>Nystatin (Fungicidin) APExBIO Techno […]<\/p>\n","protected":false},"author":3,"featured_media":34308,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[4988],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/34625"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=34625"}],"version-history":[{"count":7,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/34625\/revisions"}],"predecessor-version":[{"id":53707,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/34625\/revisions\/53707"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/34308"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=34625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=34625"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=34625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}