{"id":31262,"date":"2022-03-21T13:00:34","date_gmt":"2022-03-21T05:00:34","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=31262"},"modified":"2022-07-19T11:49:24","modified_gmt":"2022-07-19T03:49:24","slug":"mouse-anti-mouse-h-2kdh-2dd-unlb-34-1-2s%e6%8a%97%e9%ab%94-southernbiotech%e8%b2%a8%e8%99%9f1911-01","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=31262","title":{"rendered":"Mouse Anti-Mouse H-2Kd\/H-2Dd-UNLB (34-1-2S)\u6297\u9ad4 | Southernbiotech\u8ca8\u865f1911-01"},"content":{"rendered":"

Mouse Anti-Mouse H-2Kd\/H-2Dd-UNLB (34-1-2S)\u6297\u9ad4 | \u8ca8\u865f1911-01\u00a0 \u00a0\u00a0\u898f\u683c0.5 mg\u672a\u6a19\u8a8c<\/a><\/span><\/p>\n

Purified Anti-Mouse H-2Kd<\/sup>\/H-2Dd<\/sup>\u00a0antibody for use in flow cytometry, immunocytochemistry, electron microscopy, immunoprecipitation, CMCD, blocking, and adhesion assays.<\/p>\n

\u7d30\u80de\u514d\u75ab\u5c08\u5bb6\u6975\u529b\u63a8\u85a6SouthernBiotech\u9ad8\u54c1\u8cea\u4e8c\u7d1a\u6297\u9ad4<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Clone<\/strong><\/td>\n34-1-2S<\/td>\n<\/tr>\n
Isotype<\/strong><\/td>\nMouse (C3H) IgG2a<\/sub>\u03ba<\/td>\n<\/tr>\n
Isotype Control<\/strong><\/td>\nMouse IgG2a-UNLB (HOPC-1)<\/a><\/td>\n<\/tr>\n
Specificity<\/strong><\/td>\nMouse H-2Kd<\/sup>\/H-2Dd<\/sup><\/td>\n<\/tr>\n
Alternative Names<\/strong><\/td>\nMHC Class I<\/td>\n<\/tr>\n
Description<\/strong><\/td>\nThe \u201cclassical\u201d MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic \u03b1 chains noncovalently associated with the invariant \u03b22<\/sub>-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+<\/sup>\u00a0T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+<\/sup>\u00a0T cells during T cell ontogeny. The monoclonal antibody 34-1-2S binds to a common determinant in the \u03b13 domains of H-2Kd<\/sup>\u00a0and H-2Dd<\/sup>\u00a0in the presence or absence of \u03b22<\/sub>\u00a0microglobulin. It cross reacts with the \u03b13 domain of H-2Kb<\/sup>.<\/td>\n<\/tr>\n
Immunogen<\/strong><\/td>\nBDF1<\/sub>\u00a0mouse splenocytes<\/td>\n<\/tr>\n
Conjugate<\/strong><\/td>\nUNLB (Unconjugated)<\/td>\n<\/tr>\n
Buffer Formulation<\/strong><\/td>\nBorate buffered saline, pH 8.2<\/td>\n<\/tr>\n
Clonality<\/strong><\/td>\nMonoclonal<\/td>\n<\/tr>\n
Concentration<\/strong><\/td>\n0.5 mg\/mL<\/td>\n<\/tr>\n
Volume<\/strong><\/td>\n1.0 mL<\/td>\n<\/tr>\n
Recommended Storage<\/strong><\/td>\n2-8\u00b0C<\/td>\n<\/tr>\n
Applications<\/strong><\/td>\nFlow Cytometry \u2013 Quality tested\u00a03,4<\/sup>
\nImmunocytochemistry \u2013 Reported in literature\u00a03,5<\/sup>
\nElectron Microscopy \u2013 Reported in literature\u00a04<\/sup>
\nImmunoprecipitation \u2013 Reported in literature\u00a02<\/sup>
\nComplement Mediated Cell Depletion \u2013 Reported in literature\u00a03<\/sup>
\nBlocking \u2013 Reported in literature\u00a06<\/sup>
\nAdhesion \u2013 Reported in literature\u00a06<\/sup><\/td>\n<\/tr>\n
RRID Number<\/strong><\/td>\nAB_2795496<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n14972<\/a>\u00a0(Mouse)
\n14964<\/a>\u00a0(Mouse)<\/td>\n<\/tr>\n
Gene ID Symbol<\/strong><\/td>\nH2-K1<\/a>\u00a0(Mouse)
\nH2-D1<\/a>\u00a0(Mouse)<\/td>\n<\/tr>\n
Gene ID Aliases<\/strong><\/td>\nK-f; H-2K; H2-K; H2-D1; H-2K(d); H-2D; H2-D; H2-K1<\/td>\n<\/tr>\n
UniProt ID<\/strong><\/td>\nP01902<\/a>\u00a0(Mouse)
\nP01900<\/a>\u00a0(Mouse)<\/td>\n<\/tr>\n
UniProt Name<\/strong><\/td>\nHA1D_MOUSE<\/a>\u00a0(Mouse)
\nHA12_MOUSE<\/a>\u00a0(Mouse)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u00e5\u0093\u0081\u00e7\u0089\u008c\u00e4\u00bb\u008b\u00e7\u00b4\u00b9\"<\/p>\n

\u7f8e\u570b\u6297\u9ad4\u751f\u7522\u5546Southern Biotech\u65bc1982\u5e74\uff0c\u7531UAB\u7d30\u80de\u514d\u75ab\u5c08\u5bb6Dr. Max Cooper\u8207\u5be6\u9a57\u5ba4\u6210\u54e1\u5171\u540c\u5275\u7acb\u3002SouthernBiotech\u81f4\u529b\u65bc\u751f\u7522\u9ad8\u54c1\u8cea\u4e8c\u7d1a\u6297\u9ad4\u3002\u7269\u7a2e\u7a2e\u985e\u9f4a\u5168\uff0c\u5305\u62ec\u6709Bovine\u3001Canine\u3001Chicken\u3001Cynomolgus\u3001Donkey\u3001Equine\u3001Feline\u3001Goat\u3001Guinea Pig\u3001Hamster\u3001Human\u3001Monkey\u3001Mouse\u3001Porcine\u3001Rabbit\u3001Rat\u3001Rhesus\u3001Sheep\u3001Turkey\u3002\u5177\u6709\u87a2\u5149\u7269\u8cea\uff08FITC\u3001PE\u3001APC\u3001SPRD\u3001PE\/CY5.5\u3001APC\/CY5.5\u3001Spectral Red\u3001Alexa 488\u3001Alexa 647\u3001Pacific Blue\uff09\u5404\u7a2e\u87a2\u5149\u6a19\u8a8c\u3001\u53e6\u5177\u9175\u7d20\uff08HRP\u3001AP\uff09\u3001\u6216\u672a\u6a19\u8a8c\u53caLow Endotoxin\/Azide Free\uff08LE\/AF\uff09\u7b49\u6a19\u5b9a\u3002<\/p>\n

\"SouthernBiotech0100-01\"<\/a><\/p>\n

\"\u00e5\u00bc\u0095\u00e7\u0094\u00a8\u00e6\u0096\u0087\u00e7\u008d\u00bb\"<\/p>\n

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  1. Ozato K, Mayer NM, Sachs DH. Monoclonal antibodies to mouse major histocompatibility complex antigens. IV. A series of hybridoma clones producing anti-H-2d<\/sup>antibodies and an examination of expression of H-2d<\/sup>\u00a0antigens on the surface of these cells. Transplantation. 1982;34:113-9. (Immunogen)<\/li>\n
  2. Burgert H, Maryanski JL, Kvist S. “E3\/19K” protein of adenovirus type 2 inhibits lysis of cytolytic T lymphocytes by blocking cell-surface expression of histocompatibility class I antigens. Proc Natl Acad Sci USA. 1987;84:1356-60. (IP)<\/li>\n
  3. Lenz A, Heufler C, Rammensee H, Glassl H, Koch F, Romani N, et al. Murine epidermal Langerhans cells express significant amounts of class I major histocompatibility complex antigens. Proc Natl Acad Sci USA. 1989;86:7527-31. (FC, ICC, CMDC)<\/li>\n
  4. Pereira RA, Simmons A. Cell surface expression of H2 antigens on primary sensory neurons in response to acute but not latent herpes simplex virus infection in vivo. J Virol. 1999;73:6484-9. (FC, EM)<\/li>\n
  5. Abendroth A, Simmons A, Efstathiou S, Pereira RA. Infection with an H2 recombinant herpes simplex virus vector results in expression of MHC class I antigens on the surfaces of human neuroblastoma cells in vitro and mouse sensory neurons in vivo. J Gen Virol. 2000;81:2375-83. (ICC)<\/li>\n
  6. Brennen J, Mager D, Jefferies W, Takei F. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J Exp Med. 1994;180:2287-95. (Block, Adhesion)<\/li>\n<\/ol>\n

    Isotype control \u5206\u578b\u5c0d\u7167\u7d44<\/a> |\u5206\u578b\u5c0d\u7167\u7d44\u5957\u7d44<\/a> | \u6297\u9ad4\u5206\u578bELISA \u5957\u7d44<\/a> | anti-rabbit \u4e8c\u7d1a\u6297\u9ad4<\/a> | anti-mouse\u4e8c\u7d1a\u6297\u9ad4<\/a> |<\/p>\n

    \"\u5be6\u9a57\u8a2d\u50992\"<\/a>\"\u00e7\u008e\u00bb\u00e7\u0089\u0087\u00e6\u008e\u0083\u00e6\u008f\u008f\"<\/a>\"ELISA<\/a><\/p>\n

     <\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Mouse Anti-Mouse H-2Kd\/H-2Dd-UNLB (34-1-2S)\u6297\u9ad4 | \u8ca8\u865f1911- […]<\/p>\n","protected":false},"author":3,"featured_media":29304,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[198,3],"tags":[945],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/31262"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31262"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/31262\/revisions"}],"predecessor-version":[{"id":31264,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/31262\/revisions\/31264"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/29304"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31262"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}