{"id":29461,"date":"2021-09-23T18:52:51","date_gmt":"2021-09-23T10:52:51","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=29461"},"modified":"2022-07-19T11:59:47","modified_gmt":"2022-07-19T03:59:47","slug":"liproxstatin-1-a-ferroptosis-inhibitor-%e8%b2%a8%e8%99%9fb2312","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=29461","title":{"rendered":"Liproxstatin-1 | A ferroptosis inhibitor \u8ca8\u865fB2312"},"content":{"rendered":"

Liproxstatin-1 | A ferroptosis inhibitor<\/em><\/strong> \u8ca8\u865f<\/strong>B2312<\/a><\/span><\/p>\n

\"biovision\u00e5\u0095\u0086\u00e5\u0093\u0081\u00e6\u008f\u0092\u00e5\u009c\u0096\"<\/p>\n

\u7522\u54c1\u63cf\u8ff0:<\/strong> ferroptosis\u7684\u6709\u6548\u6291\u5236\u5291\u3002 Liproxstatin-1 \u6291\u5236\u4eba\u985e\u7d30\u80de\u548c\u5c0f\u9f20\u7f3a\u8840\/\u518d\u704c\u6ce8\u8a98\u5c0e\u7684\u7d44\u7e54\u640d\u50b7\u6a21\u578b\u4e2d\u7684ferroptosis.\u3002 \u6572\u9664\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176 4 (Gpx4) \u5df2\u88ab\u8b49\u660e\u6703\u5c0e\u81f4\u7d30\u80deferroptosis.\u3002 Liproxstatin-1 \u80fd\u5920\u6291\u5236 Gpx4 \u57fa\u56e0\u6572\u9664\u5c0f\u9f20\u7684ferroptosis\u3002<\/p>\n

\"\"<\/p>\n

\u00a0\"B2312\"<\/a><\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nN-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2′(1’H)-quinoxalin]-3′-amine<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n950455-15-9<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2089H\u2082\u2081ClN\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n340.85<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (~10 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nC1CNCCC12C(=NC3=CC=CC=C3N2)NCC4=CC(=CC=C4)Cl<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C19H21ClN4\/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18\/h1-7,12,21,24H,8-11,13H2,(H,22,23)<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nYAFQFNOUYXZVPZ-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n20931416<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u00e7\u009b\u00b8\u00e9\u0097\u009c\u00e8\u00a9\u00a6\u00e5\u008a\u0091\"\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a> | \u00a0FRAP\u6aa2\u6e2c<\/a> | \u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a> | Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a> | \u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a> | Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a> | \u8102\u8cea\u904e\u6c27\u5316\uff08MDA<\/strong>\uff09\u6e2c\u5b9a<\/strong><\/a> | <\/strong>\u652f\u93c8\u6c28\u57fa\u9178<\/strong><\/a> BCAA<\/u><\/strong>\u6aa2\u6e2c<\/u><\/strong><\/p>\n

 <\/p>\n

\"\u5be6\u9a57\u8a2d\u50992\"<\/a>\"\u5be6\u9a57\u8a2d\u50994\"<\/a>\"\u5be6\u9a57\u8a2d\u50995\"<\/a><\/p>\n

\"ELISA<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Liproxstatin-1 | A ferroptosis inhibitor \u8ca8\u865fB2312 \u7522\u54c1\u63cf\u8ff0: […]<\/p>\n","protected":false},"author":3,"featured_media":28510,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[993],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29461"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29461"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29461\/revisions"}],"predecessor-version":[{"id":29462,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29461\/revisions\/29462"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/28510"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29461"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29461"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}