{"id":26622,"date":"2020-12-18T14:40:33","date_gmt":"2020-12-18T06:40:33","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=26622"},"modified":"2022-07-19T15:38:15","modified_gmt":"2022-07-19T07:38:15","slug":"dr5trail-r2-protein-human-recombinant-his-tag-biotinylated-%e8%b2%a8%e8%99%9f10465-h08h-b","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=26622","title":{"rendered":"DR5\/TRAIL R2 Protein, Human, Recombinant (His Tag), Biotinylated | \u8ca8\u865f10465-H08H-B"},"content":{"rendered":"

DR5\/TRAIL R2 Protein, Human, Recombinant (His Tag), Biotinylated | <\/strong>\u8ca8\u865f<\/strong>10465-H08H-B<\/a><\/span><\/p>\n

\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u53d7\u9ad4\u8d85\u5bb6\u65cf\uff0c\u6210\u54e11b(TNFRSF1B)\uff0c\u4e5f\u7a31\u70ba\u6b7b\u4ea1\u53d7\u9ad45\uff0cCD262\uff0cTNF\u76f8\u95dc\u51cb\u4ea1\u8a98\u5c0e\u914d\u9ad4\u53d7\u9ad42 \uff08TNF-related apoptosis-inducing ligand receptor 2, TRAIL R2\uff09\uff0c\u662fTNF\u53d7\u9ad4\u8d85\u5bb6\u65cf\u7684\u6210\u54e1\uff0c\u5305\u542b\u7d30\u80de\u5167\u6b7b\u4ea1\u9818\u57df\u3002\u8a72\u53d7\u9ad4\u53ef\u4ee5\u88ab\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u76f8\u95dc\u7684\u51cb\u4ea1\u8a98\u5c0e\u914d\u9ad4\uff08tumor necrosis factor-related apoptosis inducing ligand , TNFSF1 \/ TRAIL \/ APO-2L\uff09\u6fc0\u6d3b\uff0c\u4e26\u8f49\u5c0e\u51cb\u4ea1\u4fe1\u865f\u3002\u5c0dFADD\u7f3a\u9677\u5c0f\u9f20\u7684\u7814\u7a76\u8868\u660e\uff0cFADD\uff08\u4e00\u7a2e\u542b\u6709\u929c\u63a5\u86cb\u767d\u7684\u6b7b\u4ea1\u57df\uff09\u662f\u8a72\u86cb\u767d\u4ecb\u5c0e\u7684\u51cb\u4ea1\u6240\u5fc5\u9700\u7684\u3002 TRAIL R2 \/ CD262 \/ TNFRSF1B\u4f5c\u70ba\u5728\u5169\u500b\u4e0d\u540c\u7684\u4eba\u985e\u7d30\u80de\u7cfb\u8868\u9762\u4e0a\u53ef\u6aa2\u6e2c\u5230\u7684TRAIL\u7684\u552f\u4e00\u53d7\u9ad4\u88ab\u7368\u7acb\u7d14\u5316\uff0c\u8a72\u7d30\u80de\u7cfb\u5728\u53d7\u5230TRAIL\u523a\u6fc0\u5f8c\u767c\u751f\u51cb\u4ea1\u3002 TRAIL R2 \/ CD262 \/ TNFRSF1B\u5305\u542b\u5169\u500b\u5bcc\u542b\u80de\u5916\u534a\u80f1\u6c28\u9178\u7684\u91cd\u8907\u5e8f\u5217\uff0c\u901a\u5e38\u662fTNF\u53d7\u9ad4\uff08TNFR\uff09\u5bb6\u65cf\u6210\u54e1\u548c\u4e00\u500b\u7d30\u80de\u8cea\u6b7b\u4ea1\u57df\u3002 TRAIL R2 \/ CD262 \/ TNFRSF1B\u901a\u904e\u7d30\u80de\u5167\u929c\u63a5\u5b50\u5206\u5b50FADD \/ MORT1\u4ecb\u5c0e\u51cb\u4ea1\u3002 TRAIL\u53d7\u9ad4\u65e2\u53ef\u4ee5\u767c\u51fa\u6b7b\u4ea1\u4fe1\u865f\uff0c\u53c8\u53ef\u4ee5\u767c\u51fa\u57fa\u56e0\u8f49\u9304\u4fe1\u865f\uff0c\u5176\u529f\u80fd\u8b93\u4eba\u60f3\u8d77TNFR1\u548cTRAMP\uff08\u6b7b\u4ea1\u53d7\u9ad4\u5bb6\u65cf\u7684\u53e6\u5916\u5169\u500b\u6210\u54e1\uff09\u7684\u529f\u80fd\u3002 TRAIL R2 \/ CD262 \/ TNFRSF1B\u4e2d\u7684\u7f3a\u9677\u53ef\u80fd\u662f\u5f15\u8d77\u982d\u9838\u90e8\u9c57\u72c0\u7d30\u80de\u764c\uff08neck squamous cell carcinomas , HNSCC\uff09\u7684\u539f\u56e0\uff0c\u4e5f\u88ab\u7a31\u70ba\u982d\u9838\u90e8\u9c57\u72c0\u7d30\u80de\u764c(carcinoma of the head and neck)\u3002<\/p>\n

\u00a0<\/em><\/strong>\u7522\u54c1\u63cf\u8ff0:<\/strong> TNFRSF10B\uff08NP_003833.3\uff09\u7d30\u80de\u5916\u7d50\u69cb\u57df\uff08Met1-Glu182\uff09\u7684DNA\u5e8f\u5217\u3002C\u7aef\u5177HIS\uff0c\u7d14\u5316\u7684\u86cb\u767d\u8cea\u5728\u9ad4\u5916\u88ab\u751f\u7269\u7d20\u5316\u3002A DNA sequence encoding the human TNFRSF10B (NP_003833.3) extracellular domain (Met1-Glu182) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro.<\/p>\n

\"\"<\/p>\n

Purity<\/strong><\/p>\n

> 95 % as determined by SDS-PAGE.<\/p>\n

Endotoxin<\/strong><\/p>\n

< 1.0 EU per \u03bcg protein as determined by the LAL method.<\/p>\n

Activity<\/strong><\/p>\n

Testing in progress<\/p>\n

Protein Construction<\/strong><\/p>\n

A DNA sequence encoding the human TNFRSF10B (NP_003833.3) extracellular domain (Met1-Glu182) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro.<\/p>\n

Accession#<\/strong><\/p>\n

NP_003833.3<\/a><\/p>\n

Expressed Host<\/strong><\/p>\n

HEK293 Cells<\/p>\n

Species<\/strong><\/p>\n

Human<\/p>\n

Predicted N Terminal<\/strong><\/p>\n

Ile 56<\/p>\n

Molecule Mass<\/strong><\/p>\n

The recombinant human TNFRSF10B consists of 138 amino acids and predicts a molecular mass of\u00a015.8 kDa.<\/p>\n

Formulation<\/strong><\/p>\n

Lyophilized from sterile PBS, pH 7.4
\nPlease\u00a0contact us<\/a>\u00a0for any concerns or special requirements.
\nNormally 5 % – 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.<\/p>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 <\/strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a>\u00a0|\u00a0 <\/strong>Genereach<\/strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA<\/strong>\u5100\u5668<\/strong><\/a><\/span><\/p>\n

 <\/p>\n

\u00a0<\/strong><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

DR5\/TRAIL R2 Protein, Human, Recombinant (His Tag), Bio […]<\/p>\n","protected":false},"author":3,"featured_media":3546,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1270,1267,1268,1269],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26622"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26622"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26622\/revisions"}],"predecessor-version":[{"id":26623,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26622\/revisions\/26623"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/3546"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26622"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26622"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26622"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}