{"id":26103,"date":"2020-11-05T14:33:35","date_gmt":"2020-11-05T06:33:35","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=26103"},"modified":"2022-07-19T16:14:28","modified_gmt":"2022-07-19T08:14:28","slug":"%e9%bb%83%e8%8a%aa%e9%bb%83%e9%85%ae-astragalin%e8%b2%a8%e8%99%9fb2964","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=26103","title":{"rendered":"\u9ec3\u82aa\u9ec3\u916e | Astragalin\u8ca8\u865fB2964"},"content":{"rendered":"

\u9ec3\u82aa\u9ec3\u916e(Astragalin) | <\/strong>Astragalin\u8ca8\u865f<\/strong>B2964<\/a><\/span><\/p>\n

\u7522\u54c1\u63cf\u8ff0:<\/strong> \u00a0\u9ec3\u82aa\u9ec3\u916e(Astragalin) \u5177\u6709\u6297\u708e\u548c\u6297\u6c27\u5316\u6d3b\u6027\u7684\u985e\u9ec3\u916e,\u662f\u5f9e\u67ff\u5b50(persimmon)\uff0c\u7da0\u8336\u7a2e\u5b50(green tea seeds)\uff0c\u8461\u8404\u9152(wine)\u548c\u7f8e\u6d32\u5546\u9678\u7684\u8449\u5b50(American pokeweed)\u4e2d\u5206\u96e2\u51fa\u7684\u985e\u9ec3\u916e(flavonoid)\u3002\u5b83\u986f\u793a\u51fa\u6297\u708e(anti-inflammatory)\u548c\u6297\u6c27\u5316(anti-oxidant activity)\u7684\u6d3b\u6027\u3002\u5291\u91cf\u4f9d\u8cf4\u6027(dose-dependently)\uff0820-80 \u00b5g \/ ml\uff09\u6291\u5236\u6e90\u81ea\u60a3\u8005\u7684\u9aa8\u95dc\u7bc0\u708e\u8edf\u9aa8\u7d30\u80de\u4e2dIL-1\u03b2\u523a\u6fc0\u7684\u4e00\u6c27\u5316\u6c2e(nitric oxide)\u548c\u524d\u5217\u817a\u7d20E2\uff08prostaglandin , PGE2\uff09\u7684\u7522\u751f\u3002\u5b83\u9084\u6291\u5236IL-1\u03b2\u523a\u6fc0\u7684\u4e00\u6c27\u5316\u6c2e\u5408\u9176\uff08nitric oxide synthase , NOS\uff09\uff0cCOX-2\u7684\u8868\u9054\u4ee5\u53caMAPK\u548cNF-\u03baB\u4fe1\u865f\u7684\u6fc0\u6d3b(activation)\u30021-20 \u00b5M\u5291\u91cf\u4f9d\u8cf4\u6027\u5730\u9632\u6b62\u4e86\u904e\u6c27\u5316\u6c2b\u66b4\u9732\u7684\u4eba\u652f\u6c23\u7ba1\u4e0a\u76ae\u7d30\u80de\u4e2dE-\u9223\u7c98\u86cb\u767d(E-cadherin)\u7684\u640d\u5931\uff0c\u6ce2\u5f62\u86cb\u767d(vimentin)\u7684\u8868\u9054\u4ee5\u53ca1\u578b\u81a0\u539f(collagen type-1)\u7684\u7522\u751f.\uff0810-20 mg \/ kg\uff0cp.o.\uff09\u9084\u53ef\u4ee5\u964d\u4f4e\u5c0f\u9f20\u7684\u4e0a\u76ae\u80ba\u7d44\u7e54\u4e2d\u7684\u6d3b\u6027\u6c27\uff08ROS\uff09\u7522\u751f\uff0c\u81a0\u539f\u7e96\u7dad\u6c89\u7a4d\u548c\u81ea\u566c\u9ad4\u5f62\u6210\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; kaempferol-3-glucoside; 3-(\u03b2-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Kaempferol 3-\u03b2-D-glucopyranoside; 3,4\u2032,5,7-Tetrahydroxyflavone 3-glucoside<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nSolid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n480-10-4<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2081H\u2082\u2080O\u2081\u2081<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n448.38<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n95%<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\n~30 mg\/ml in DMSO and DMF<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nC1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C21H20O11\/c22-7-13-15(26)17(28)18(29)21(31-13)32-20-16(27)14-11(25)5-10(24)6-12(14)30-19(20)8-1-3-9(23)4-2-8\/h1-6,13,15,17-18,21-26,28-29H,7H2\/t13-,15-,17+,18-,21+\/m1\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nJPUKWEQWGBDDQB-QSOFNFLRSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n5282102<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00baC<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nRT<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a> | \u00a0FRAP\u6aa2\u6e2c<\/a> | \u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a> | Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a> | \u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a> | Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a> | \u8102\u8cea\u904e\u6c27\u5316\uff08MDA\uff09\u6e2c\u5b9a<\/a> | <\/strong>\u652f\u93c8\u6c28\u57fa\u9178<\/a> BCAA<\/u><\/strong>\u6aa2\u6e2c<\/u><\/strong><\/span><\/p>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 \u5fae\u91cf\u5206\u6ce8\u5668<\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/a>\u00a0|\u00a0 <\/strong>Genereach\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA\u5100\u5668<\/a><\/span><\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u9ec3\u82aa\u9ec3\u916e(Astragalin) | Astragalin\u8ca8\u865fB2964 \u7522\u54c1\u63cf\u8ff0: \u00a0\u9ec3\u82aa\u9ec3\u916e(Astrag […]<\/p>\n","protected":false},"author":3,"featured_media":26104,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1364],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26103"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26103"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26103\/revisions"}],"predecessor-version":[{"id":26105,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/26103\/revisions\/26105"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/26104"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26103"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}