{"id":25846,"date":"2020-08-31T16:00:51","date_gmt":"2020-08-31T08:00:51","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=25846"},"modified":"2023-02-22T10:53:48","modified_gmt":"2023-02-22T02:53:48","slug":"gsk-3%ce%b1-antibody%e6%8a%97%e9%ab%94-%e8%b2%a8%e8%99%9f6676-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=25846","title":{"rendered":"GSK-3\u03b1 Antibody\u6297\u9ad4 | \u8ca8\u865f6676-100 (Abcam ab40870)"},"content":{"rendered":"

GSK-3\u03b1 Antibody\u6297\u9ad4 | \u00a0\u8ca8\u865f<\/strong>6676-100<\/a>\u00a0(Abcam ab40870)\u00a0<\/span><\/p>\n

Polyclonal Antibody to detect GSK-3\u03b1 in human samples<\/em><\/strong><\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u7cd6\u539f\u5408\u9176\u6fc0\u91763-alpha(Glycogen synthase kinase 3-alpha, GSK-3)\u662f\u4e00\u7a2e\u591a\u529f\u80fd\u86cb\u767d\u7d72\u6c28\u9178\u6fc0\u9176(multifunctional protein serine kinase)\u3002 GSK-3\u78f7\u9178\u5316(GSK-3 phosphorylates\u4e26)\u4f7f\u7cd6\u539f\u5408\u9176\u5931\u6d3b(inactivates glycogen synthase)\u3002 \u5b83\u4e5f\u88ab\u727d\u9023\u5230\u4e86\u68ad\u83cc\u7684\u7d30\u80de\u547d\u904b\u7684\u8abf\u7bc0\u4e2d\uff0c\u4e26\u4e14\u662f\u679c\u8805\uff0c\u975e\u6d32\u722a\u87fe\u548c\u54fa\u4e73\u52d5\u7269\u767c\u80b2\u6240\u9700\u7684Wnt\u4fe1\u865f\u50b3\u5c0e\u9014\u5f91\u7684\u7d44\u6210\u90e8\u5206\u3002 GSK-3\u5df2\u88ab\u8b49\u660e\u53ef\u8abf\u7bc0Cyclin D1\u86cb\u767d\u6c34\u89e3(Cyclin D1 proteolysis)\u548c\u4e9e\u7d30\u80de\u5b9a\u4f4d(subcellular localization)\u3002 GSK-3alpha\uff08GSK-3\u03b1\uff09\u901a\u904e\u78f7\u9178\u5316Tau\u86cb\u767d\u4f86\u8abf\u7bc0\u6fb1\u7c89\u6a23\u86cb\u767d\u03b2\u80bd\uff08\u6591\u584a\u7684\u4e3b\u8981\u6210\u5206\uff0c\u5176\u96a8\u8457\u963f\u723e\u8328\u6d77\u9ed8\u6c0f\u75c5\u7684\u9032\u5c55\u800c\u7a4d\u7d2f\uff09\u7684\u7522\u751f\u3002 \u9019\u8868\u660eGSK-3\u4fe1\u865f\u7f3a\u9677\u53ef\u80fd\u5c0e\u81f4\u963f\u723e\u8328\u6d77\u9ed8\u6c0f\u75c5\u7684\u767c\u4f5c\u3002 GSK-3\u03b1\u53ef\u4ee5\u88abSer21\u7684Akt\u78f7\u9178\u5316\u3002 GSK-3\u03b1\u7684\u9019\u7a2e\u78f7\u9178\u5316\u8ca0\u8abf\u7bc0\u5176\u6fc0\u9176\u6d3b\u6027\u3002<\/p>\n

\"\"<\/p>\n

\"\"<\/p>\n

\u86cb\u767d\u8cea\u5370\u8de1 – \u6297 GSK3 \u03b1 \u6297\u9ad4 [EP793Y] (ab40870)<\/strong><\/div>\n
\u6240\u6709\u6cf3\u9053\uff1a<\/b>\u00a01\/1000 \u7a00\u91cb\u5ea6\u7684\u6297 GSK3 \u03b1 \u6297\u9ad4 [EP793Y] (ab40870) \u6cf3\u9053<\/p>\n

1\uff1a<\/b>\u91ce\u751f\u578b HEK-293T\uff08\u4f86\u81ea\u7528\u5927 T \u6297\u539f\u8f49\u5316\u7684\u80da\u80ce\u814e\u7684\u4eba\u4e0a\u76ae\u7d30\u80de\u7cfb\uff09\u5168\u7d30\u80de\u88c2\u89e3\u7269 \u6cf3\u9053
\n2\uff1a<\/b>\u00a0GSK3A \u6572\u9664HEK-293T\uff08\u4f86\u81ea\u7528\u5927 T \u6297\u539f\u8f49\u5316\u7684\u80da\u80ce\u814e\u7684\u4eba\u4e0a\u76ae\u7d30\u80de\u7cfb\uff09\u5168\u7d30\u80de\u88c2\u89e3\u7269 \u6cf3\u9053
\n3\uff1a<\/b>\u00a0HeLa\uff08\u4f86\u81ea\u5bae\u9838\u817a\u764c\u7684\u4eba\u4e0a\u76ae\u7d30\u80de\u7cfb\uff09\u5168\u7d30\u80de\u88c2\u89e3\u7269 \u6cf3\u9053
\n4\uff1a<\/b>\u00a0HepG2\uff08\u4eba\u809d\u809d\u764c\u7d30\u80de\u7cfb\uff09\u5168\u7d30\u80de\u88c2\u89e3<\/div>\n

<\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Antibody Target<\/strong><\/td>\nGSK-3\u03b1<\/td>\n<\/tr>\n
Alternate Name<\/strong><\/td>\nSerine\/threonine-protein kinase GSK3A, GSK-3alpha, Glycogen synthase kinase-3, GSK-3 alpha<\/td>\n<\/tr>\n
Host<\/strong><\/td>\nRabbit<\/td>\n<\/tr>\n
Antibody Type<\/strong><\/td>\nPolyclonal<\/td>\n<\/tr>\n
Isotype<\/strong><\/td>\nRabbit IgG<\/td>\n<\/tr>\n
Immunogen<\/strong><\/td>\nHuman recombinant GSK-3\u03b1 (Cat # 7003)<\/td>\n<\/tr>\n
Accession #<\/strong><\/td>\nP49840<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n2931<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nColorless liquid<\/td>\n<\/tr>\n
Concentration<\/strong><\/td>\n0.5 mg\/ml<\/td>\n<\/tr>\n
Formulation<\/strong><\/td>\n100 \u00b5g (0.5 mg\/ml) of GSK-3\u03b1 antibody in PBS pH 7.2, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.<\/td>\n<\/tr>\n
Purification<\/strong><\/td>\nAffinity Purified Antibody<\/td>\n<\/tr>\n
Species Reactivity<\/strong><\/td>\nHuman<\/td>\n<\/tr>\n
Application<\/strong><\/td>\nWestern blot<\/td>\n<\/tr>\n
Positive Control<\/strong><\/td>\nWestern Blot: 3T3 cell lysate<\/td>\n<\/tr>\n
Application & Usage<\/strong><\/td>\nWestern blot: 1-4 \u00b5g<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nThe antibody solution should be gently mixed before use.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20 \u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a> | \u00a0FRAP\u6aa2\u6e2c<\/a> | \u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a> | Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a> | \u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a> | Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a> | \u8102\u8cea\u904e\u6c27\u5316\uff08<\/strong>MDA<\/strong>\uff09\u6e2c\u5b9a<\/strong><\/a> | <\/strong>\u652f\u93c8\u6c28\u57fa\u9178<\/strong><\/a> BCAA<\/u><\/strong>\u6aa2\u6e2c<\/u><\/strong><\/p>\n\n\n\n\n\n\n\n\n
<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
\u8ca8\u865f9210<\/td>\n\u91cd\u7d44\u86cb\u767d\u9176K (\u5206\u5b50\u7b49\u7d1aRNase\/DNase free)<\/a><\/td>\n100 mg, 500 mg, 1 g, 10 g, 50 g<\/td>\n\u7d14\u5ea6 99% (Native PAGE and SDS PAGE assay)<\/td>\n<\/tr>\n
\u8ca8\u865f9211-5<\/td>\n\u91cd\u7d44\u86cb\u767d\u9176K (\u5206\u5b50\u7b49\u7d1aRNase\/DNase free)<\/a><\/td>\n5 ml, 25 ml, 100 m (20 mg\/ml Solution)<\/td>\n\u7d14\u5ea6 99% (Native PAGE and SDS PAGE assay)<\/td>\n<\/tr>\n
\u8ca8\u865f9247<\/td>\n\u91cd\u7d44\u86cb\u767d\u9176K (NGS\u7b49\u7d1a)<\/a><\/td>\n100 mg, 500 mg, 1 g, 10 g<\/td>\n\n

\u91cd\u7d44\u9176\u5728Pichia pastoris\u4e2d\u8868\u9054\uff0c<\/p>\n

\u4e26\u9032\u884c\u5ee3\u6cdb\u7684\u7d14\u5316\u4ee5\u7372\u5f97\u6700\u9ad8\u7684<\/p>\n

\u512a\u8cea\u7684\u7522\u54c1\u3002\u984d\u5916\u7684\u7d14\u5316\u6b65\u9a5f\u5c0e\u81f4<\/p>\n

\u6eb6\u89e3\u5ea6\u986f\u8457\u589e\u52a0\uff082.5\u500d\uff09\uff0c\u589e\u52a0<\/p>\n

\u6bd4\u6d3b\u6027\u548c\u6e1b\u5c11\u7684DNA\u542b\u91cf<\/p>\n

 <\/td>\n<\/tr>\n

\u8ca8\u865f9250<\/a><\/td>\n\u91cd\u7d44\u86cb\u767d\u9176K (\u6a19\u6e96\u7b49\u7d1a)<\/a><\/td>\n5 ml, 25 ml, 100 m (20 mg\/ml Solution)<\/td>\n\u7d14\u5ea6>90%<\/td>\n<\/tr>\n
\u8ca8\u865f9251<\/a><\/td>\n\u91cd\u7d44\u86cb\u767d\u9176K (\u6a19\u6e96\u7b49\u7d1a)<\/a><\/td>\n100 mg, 500 mg ,1 g ,10 g<\/td>\n\u7d14\u5ea6>90%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

GSK-3\u03b1 Antibody\u6297\u9ad4 | \u00a0\u8ca8\u865f6676-100\u00a0(Abcam ab40870)\u00a0 Polycl […]<\/p>\n","protected":false},"author":3,"featured_media":5871,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[1408],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25846"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25846"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25846\/revisions"}],"predecessor-version":[{"id":38742,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25846\/revisions\/38742"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/5871"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25846"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}