{"id":25694,"date":"2020-08-05T16:04:50","date_gmt":"2020-08-05T08:04:50","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=25694"},"modified":"2022-07-19T16:49:58","modified_gmt":"2022-07-19T08:49:58","slug":"anti-blc2-bcl-2124%e6%8a%97%e9%ab%94-anti-blc2-bcl-2124-mouse-igg1-kappa%e8%b2%a8%e8%99%9fab01322-1-1","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=25694","title":{"rendered":"Anti-BLC2 [bcl-2\/124]\u6297\u9ad4 | Anti-BLC2 [bcl-2\/124], Mouse IgG1, Kappa\u8ca8\u865fAb01322-1.1"},"content":{"rendered":"

Anti-BLC2 [bcl-2\/124]\u6297\u9ad4 | Anti-BLC2 [bcl-2\/124], Mouse IgG1, Kappa\u8ca8\u865fAb01322-1.1<\/a> \u00a0\u00a0<\/strong><\/span><\/p>\n

\u6297\u9ad4\u4ecb\u7d39<\/strong>:<\/strong>\u00a0\u8a72\u6297\u9ad4\u8b58\u5225\u4ebaBLC-2\uff0c\u5b83\u662f\u591a\u7a2e\u7d30\u80de\u985e\u578b\u4e2d\u7684\u6297\u51cb\u4ea1\u56e0\u5b50\u3002\u5b83\u7684\u5931\u8abf\u727d\u6d89\u5230\u4e0d\u540c\u7684\u72c0\u6cc1\uff0c\u4f8b\u5982\u764c\u75c7\u548c\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u6b64\u6297\u9ad4\u53ef\u61c9\u7528\u65bcBlocking, ELISA, FC\u7b49\u5be6\u9a57\u3002<\/p>\n

Alternative Name(s) of Target: Apoptosis regulator Bcl-2; AW986256; B-cell CLL\/lymphoma 2; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik; protein phosphatase 1; regulatory subunit 50; bcl-2-124; bcl2\/124<\/p>\n

\u514d\u75ab\u539f(Immunogen): This antibody was raised against a synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein.<\/p>\n

Clone Name: 1B4\u3002Published Application(s): Blocking, ELISA, FC<\/p>\n

Alternative Name(s) of Target: Apoptosis regulator Bcl-2; AW986256; B-cell CLL\/lymphoma 2; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik; protein phosphatase 1; regulatory subunit 50; bcl-2-124; bcl2\/124<\/p>\n

Immunogen: This antibody was raised against a synthetic peptide of amino acids 41-54 of human bcl-2 oncoprotein.<\/p>\n

Specificity: This antibody recognises human BLC-2 which is an antiapoptotic factor in various cell types. Its disregulation was implicated in different conditions, such as cancers and autoimmune disorders.<\/p>\n

Application Notes: This antibody has been used extensively in attempts aimed at characterising various cancer tissues via immunohistochemical staining. One group used bcl-2-124 antibody to label large B-cell lymphoma samples for bcl2 in order to perform its immunophenotypic and genetic depiction (Chang et al., 2016). Another group took advantage of this antibody while analysing the molecular picture of a case of the cystic synovial sarcoma of the pleura where they observed positive immunohistochemical staining in tumor cells (Tajima et al., 2015). Bcl-2 plays an important role as an inhibitor of apoptosis and its identification is often useful while analysing various factors influencing apoptosis. For instance, bcl-2\/124 antibody has been successfully utilised in such experiments identifying bcl-2 via Western blot – Gomez-Bougie (2007) probed the influence of bortezomib on HMCL cells and detected bcl-2 signal on Western blots.<\/p>\n

Antibody first published in: Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation. Am J Pathol. 1990 Aug;137(2):225-32. PMID:2201196 Note on publication: This article describes generation and characterisation of the bcl-2\/124 antibody.<\/p>\n

Purified antibody.<\/p>\n

Purification:<\/strong>\u00a0Protein A affinity purified<\/p>\n

Supplied in:<\/strong>\u00a0PBS with 0.02% Proclin 300.<\/p>\n

Storage Recommendation:<\/strong>\u00a0Store at 4\u2070C for up to 3 months. For longer storage, aliquot and store at -20\u2070C.<\/p>\n

Concentration:<\/strong>\u00a01 mg\/ml.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u7522\u54c1\u8ca8\u865f<\/td>\nMouse target<\/td>\n\u6297\u9ad4clone<\/td>\nOriginal Antibody format<\/td>\n<\/tr>\n
Ab01052<\/a><\/td>\n4-1BB (CD137)<\/td>\nLOB12.3<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n<\/thead>\n
Ab01054<\/a><\/td>\n4-1BBL (CD137L)<\/td>\nAT113-2<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab00881<\/a><\/td>\n4-1BBL (CD137L)<\/td>\nTKS-1<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01027<\/a><\/td>\nBTLA<\/td>\nHMBT-6B2
\n<\/a><\/td>\n		Hamster IgG<\/td>\n<\/tr>\n
Ab00670<\/a><\/td>\nCD27<\/td>\nLG.3A10<\/a><\/td>\nHamster IgG<\/td>\n<\/tr>\n
Ab00895<\/a><\/td>\nCD27<\/td>\n\n

RM27-3E5<\/a><\/p>\n

 <\/td>\n

Rat IgG2a<\/td>\n<\/tr>\n
Ab00286<\/a><\/td>\nCD28<\/td>\nE18
\n<\/a><\/td>\n		Mouse IgG2b<\/td>\n<\/tr>\n
Ab00285<\/a><\/td>\nCD28<\/td>\nD665
\n<\/a><\/td>\n		Mouse IgG1<\/td>\n<\/tr>\n
Ab01109<\/a><\/td>\nCD40<\/td>\n3\/23
\n<\/a><\/td>\n		Rat IgG2a<\/td>\n<\/tr>\n
Ab01087<\/a><\/td>\nCD40L (CD154)<\/td>\nMR1
\n<\/a><\/td>\n		Hamster IgG<\/td>\n<\/tr>\n
Ab00816<\/a><\/td>\nCD70<\/td>\nTAN 1-7
\n<\/a><\/td>\n		Rat IgG2a<\/td>\n<\/tr>\n
Ab01056<\/a><\/td>\nCD70<\/td>\nTAN1-6
\n<\/a><\/td>\n		Rat IgG2a<\/td>\n<\/tr>\n
Ab01028<\/td>\nCD80 (B7-1)<\/td>\nRM80<\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01029<\/a><\/td>\nCD86 (B7-2)<\/td>\nPO.3<\/a><\/td>\nRat IgG2b<\/td>\n<\/tr>\n
Ab01089<\/a><\/td>\nCD153<\/td>\nRM153<\/a><\/td>\nRat IgG2b<\/td>\n<\/tr>\n
Ab01297<\/a><\/td>\nCD96<\/td>\n6A6<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab00894<\/a><\/td>\nCTLA-4<\/td>\n9H10<\/a><\/td>\nHamster IgG2<\/td>\n<\/tr>\n
Ab01018<\/a><\/td>\nCTLA-4<\/td>\n9D9<\/a><\/td>\nMouse IgG2b<\/td>\n<\/tr>\n
Ab01088<\/a><\/td>\nGAL-9<\/td>\nRG9-35<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01060<\/a><\/td>\nGITR<\/td>\nDTA-1<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab00374<\/a><\/td>\nGITR<\/td>\nYGITR 860.103.5<\/a><\/td>\nRat IgG2b<\/td>\n<\/tr>\n
Ab00631<\/a><\/td>\nGITR<\/td>\nYGITR765<\/a><\/td>\nRat IgG2b<\/td>\n<\/tr>\n
Ab00630<\/a><\/td>\nGITRL<\/td>\nYGL386<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab01026<\/a><\/td>\nHVEM<\/td>\nHMHV-1B18<\/a><\/td>\nHamster IgG<\/td>\n<\/tr>\n
Ab00814<\/a><\/td>\nICOS<\/td>\n7E.17G9<\/a><\/td>\nRat IgG2b<\/td>\n<\/tr>\n
Ab00882<\/a><\/td>\nICOSL<\/td>\nHK5.3<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01295<\/a><\/td>\nLAG3<\/td>\nC9B7W<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab01295<\/a><\/td>\nLAG3<\/td>\nC9B7W<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab00110<\/a><\/td>\nOX40 (CD134)<\/td>\nOX86<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab00564<\/a><\/td>\nOX40L<\/td>\nOX-89<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab00813<\/a><\/td>\nPD-1<\/td>\nRMP1-14<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01017<\/a><\/td>\nPD-1H (VISTA)<\/td>\nmam82<\/a><\/td>\nMouse IgG1<\/td>\n<\/tr>\n
Ab01016<\/a><\/td>\nPD-1H (VISTA)<\/td>\nMH5A<\/a><\/td>\nHamster IgG<\/td>\n<\/tr>\n
Ab00373<\/a><\/td>\nPD-L1<\/td>\nYDC 127.1.1<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab00883<\/a><\/td>\nPD-L2<\/td>\nTY25<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab00875<\/a><\/td>\nPDPN (MAP-Tag)<\/td>\nPMab-1<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab00973<\/a><\/td>\nTIGIT<\/td>\n4D4<\/a><\/td>\nHamster IgG<\/td>\n<\/tr>\n
Ab01258<\/a><\/td>\nTIGIT<\/td>\n1B4<\/a><\/td>\nMouse IgG1<\/td>\n<\/tr>\n
Ab01032<\/a><\/td>\nTIM-1<\/td>\n3B3<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01110<\/a><\/td>\nTIM-2<\/td>\nRMT2-14<\/a><\/td>\nRat IgG2a<\/td>\n<\/tr>\n
Ab01057<\/a><\/td>\nTIM-3<\/td>\n2C12<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab01058<\/a><\/td>\nTIM-4<\/td>\n5G3<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
Ab01059<\/a><\/td>\nTIM-4<\/td>\n3A1<\/a><\/td>\nRat IgG1<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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