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Absolute antibody\u00a0<\/strong>\u63d0\u4f9b\u4e00\u7cfb\u5217\u53ef\u8b58\u5225SARS-CoV-2\uff08\u4e5f\u7a31\u70ba2019-nCoV\u6216COVID-19\uff09\u7684\u6297\u51a0\u72c0\u75c5\u6bd2\u6297\u9ad4\u3002\u6297SARS\u55ae\u682a\u6297\u9ad4CR3022\u65bc2006\u5e74\u9996\u6b21\u63cf\u8ff0\uff0c\u4e26\u57282020\u5e74\u521d\uff0c\u7814\u7a76\u4eba\u54e1 (researchers showed<\/a>) \u8868\u660e\u8a72\u55ae\u682a\u6297\u9ad4\u8207\u7576\u6642\u76842019-nCoV\u5177\u6709\u9ad8\u89aa\u548c\u529b\uff0c\u53ef\u61c9\u7528\u65bccrystallography, NTRL, SPR, ELISA\u8a66\u9a57\u3002Absolute antibody \u63d0\u4f9b33\u7a2e\u4e0d\u540c\u4e4bCOVID-19\u6297\u9ad4\u00a0(available in our catalog<\/a>\u00a0)\uff0c\u4e00\u7cfb\u5217\u4eba\u985e\u00a0IgG1<\/a>\u3001\u00a0IgG1 Fc Silent<\/a>\u3001\u00a0IgG2<\/a>\u3001\u00a0IgG3<\/a>\u3001IgM<\/a>\u3001\u00a0IgA<\/a>\u3001Fab<\/a>\u3001\u00a0Fab2<\/a>\u00a0\u6297\u9ad4\uff0c\u53ef<\/span>\u7528\u65bc\u4e2d\u548c\u6e2c\u5b9a(neutralization assays) \u548c\u8840\u6e05\u5b78\u5c0d\u7167 (serological controls)\u3002<\/span>\u5154\u00a0IgG<\/a>\uff0c\u5c0f\u9f20\u00a0IgG2b<\/a>\u548c\u5c0f\u9f20\u00a0IgM<\/a>\u7528\u65bc\u6aa2\u6e2c\u61c9\u7528\uff0c\u5171\u6a19\u8a18\u7814\u7a76(co-labelling studies )\u548c\u52d5\u7269\u6a21\u578b\u7814\u7a76(\u00a0animal model research)\u3002<\/span>\u5177\u6709His\u6a19\u7c64\u7684\u4eba\u548c\u5c0f\u9f20Fab\u548cFab2<\/sup>\u6297\u9ad4\uff0c\u7528\u65bc\u9700\u8981\u6297\u9ad4\u7247\u6bb5(antibody fragments)\u7684\u61c9\u7528\u4ee5\u53ca\u4f4d\u9ede\u7279\u7570\u6027\u529f\u80fd\u5316 (site-specific functionalization)\u3002<\/span>\u5c08\u6709\u7684\u4ebaIgG1\u548c\u5c0f\u9f20IgG2b\u00a0Fc Silent\u2122 formats<\/a>\uff0c\u65e8\u5728\u8b58\u5225Fc\u4f9d\u8cf4\u6027\u548cFc\u4f9d\u8cf4\u6027\u6548\u61c9\u5b50\u529f\u80fd\uff0c\u4e26\u4fc3\u9032\u5c0d\u6297\u9ad4\u4f9d\u8cf4\u6027\u589e\u5f37\uff08ADE\uff09\u4f5c\u7528\u7684\u7814\u7a76\u3002<\/span><\/p>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]\u55ae\u682a\u6297\u9ad4 | \u8ca8\u865fAb01680-10.3\u00a0 (200UG)\u00a0Fc Silent\u2122<\/a><\/span><\/p>\n Alternative Name(s) of Target: Spike protein; COVID19; COVID 19; S protein; SARS-CoV S protein; S glycoprotein; E2; Peplomer protein; Spike protein S1; SARS Coronavirus; SARS-CoV-2; SARS CoV 2; 2019- nCoV<\/p>\n \u6297\u9ad4\u4ecb\u7d39<\/strong>:<\/strong>\uff1a\u8a72\u6297\u9ad4\u7279\u7570\u6027\u7d50\u5408SARS-CoV Spike\u86cb\u767d\u4ee5\u53caSARS-CoV-2\uff08COVID-19\uff09Spike\u86cb\u767dS1\u57df\u4e2d\u7684\u6c28\u57fa\u9178318-510\u3002\u8207SARS spike protein\u7684P462L\u53d6\u4ee3\u7684S318\u2013510\u7247\u6bb5\u7d50\u5408\u3002\u7d50\u5408\u8868\u4f4d\u50c5\u5728\u523a\u7a81\u86cb\u767d(spike protein)\u7684\u201c\u958b\u653e\u201d\u7d50\u69cb\u4e2d\u53ef\u8a2a\u554f\uff08Joyce\u7b49\u4eba\uff0c2020\uff09\u3002\u61c9\u7528\u8aaa\u660e\uff1a\u6297\u9ad4\u4ee5\u9ad8\u89aa\u548c\u529b\u8207SARS-CoV\u548cSARS-CoV-2\u7d50\u5408\uff08PMID\uff1a16796401\u548c32065055\uff09\u3002\u6297\u9ad4\u7d50\u5408\u7684\u6700\u521d\u8868\u5fb5\u662f\u901a\u904eELISA\u9032\u884c\uff0c\u5b83\u8868\u660e\u4e86\u958b\u767c\u8a3a\u65b7\u6aa2\u6e2c\u65b9\u6cd5\u7684\u6f5b\u529b\uff0c\u65e2\u53ef\u4ee5\u4f5c\u70ba\u75c5\u6bd2\u6355\u7372\u6aa2\u6e2c\u65b9\u6cd5\uff0c\u4e5f\u53ef\u4ee5\u4f5c\u70ba\u8840\u6e05\u5b78\u6aa2\u6e2c\u65b9\u6cd5\u7684\u5c0d\u7167\uff0c\u7528\u65bc\u6e2c\u91cf\u5c0d\u75c5\u6bd2\u66b4\u9732\u7684\u514d\u75ab\u53cd\u61c9\u3002\u4ebaIgG1\uff0cIgG3\uff0cIgM\u548cIgA\u540c\u7a2e\u578b\u53ef\u7528\u65bc\u6a21\u64ec\u5728COVID19\u4e2d\u770b\u5230\u7684\u6297\u9ad4\u53cd\u61c9\uff08Amanat\u7b49\u4eba2020\uff09\u3002\u4ebaIgG2\u548cIgG4\u4e9e\u578b\uff08\u4e5f\u898b\u65bcCOVID-19\u60a3\u8005\u7684\u4e00\u5c0f\u90e8\u5206\uff09\u4e5f\u53ef\u7528\u65bc\u7814\u7a76\u5176\u5728\u5c0dSARS-CoV-2\u61c9\u7b54\u4e2d\u7684\u4f5c\u7528\u3002\u8a72\u6297\u9ad4\u7684\u539f\u59cb\u4ebaIgG1\u7248\u672c\u8207\u53e6\u4e00\u7a2e\u975e\u7af6\u722d\u6027SARS\u6297\u9ad4CR3014\u5354\u540c\u4f5c\u7528\uff0c\u662f\u88ab\u52d5\u514d\u75ab\u9810\u9632SARS-CoV\u611f\u67d3\u7684\u6f5b\u5728\u5019\u9078\u85e5\u7269\uff08Meulen\u7b49\uff0c2006\uff09\u3002\u4e5f\u6709\u5831\u5c0e\u7a31\u539f\u59cb\u6297\u9ad4\uff08\u4ebaIgG1\uff09\u82072019-nCoV RBD\u7d50\u5408\uff08KD\u70ba6.3 nM\uff09\u3002\u8a72\u6297\u9ad4\u88ab\u8a8d\u70ba\u6709\u53ef\u80fd\u55ae\u7368\u6216\u8207\u5176\u4ed6\u4e2d\u548c\u6297\u9ad4\u4e00\u8d77\u958b\u767c\u4f5c\u70ba\u6cbb\u7642\u5291\u7528\u65bc\u6cbb\u76422019-nCoV\u611f\u67d3\uff08Tian\u7b49\u4eba\uff0c2020\uff09\u3002\u6297\u9ad4\u7d93\u7531Protein A affinity \u7d14\u5316\u5f8c\uff0c\u65bcPBS with 0.02% Proclin 300\u7de9\u885d\u6db2\u4e2d(1 mg\/m)\u3002<\/p>\n Antibody first published in:<\/strong>\u00a0ter Meulen et al. Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants PLoS Med. 2006 Jul; 3(7): e237\u00a0PMID:16796401<\/a> \u3010SARS-CoV-2 \/ COVID-19\u6297\u9ad4\u3011-<\/span><\/strong>\u00a0\u6297\u9ad4\u4e2d\u548c\u6e2c\u5b9a (neutralization assays) \/\u8840\u6e05\u5b78\u5c0d\u7167 (serological controls)<\/span><\/span><\/p>\n Available anti-COVID-19 antibody formats in our reagent catalog now include:<\/strong><\/p>\n <\/p>\n","protected":false},"excerpt":{"rendered":" Absolute antibody\u00a0\u63d0\u4f9b\u4e00\u7cfb\u5217\u53ef\u8b58\u5225SARS-CoV-2\uff08\u4e5f\u7a31\u70ba2019-nCoV\u6216COVID […]<\/p>\n","protected":false},"author":3,"featured_media":3519,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[1467],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25483"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25483"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25483\/revisions"}],"predecessor-version":[{"id":25489,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25483\/revisions\/25489"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/3519"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25483"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25483"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25483"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n![\"Binding](\"https:\/\/absoluteantibody.com\/wp-content\/uploads\/2020\/04\/ING00619Ab01680-10.0ELISAfull.png\")
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<\/p>\n![\"Binding](\"https:\/\/absoluteantibody.com\/wp-content\/uploads\/2020\/05\/ING00622Ab01680-10.0ELISAfull.png\")
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\n Format<\/strong><\/td>\n Catalog Number<\/strong><\/td>\n<\/tr>\n \n Human IgG1<\/a><\/td>\n Ab01680-10.0<\/td>\n<\/tr>\n \n Human IgG1 Fc Silent\u2122<\/a><\/td>\n Ab01680-10.3<\/td>\n<\/tr>\n \n Human IgG2<\/a><\/td>\n Ab01680-11.0<\/td>\n<\/tr>\n \n Human IgG3<\/a><\/td>\n Ab01680-12.1<\/td>\n<\/tr>\n \n Human IgM<\/a><\/td>\n Ab01680-15.0\u00a0<\/strong><\/td>\n<\/tr>\n \n Human IgA<\/a><\/td>\n Ab01680-16.0<\/td>\n<\/tr>\n \n Human Fab<\/a><\/td>\n Ab01680-10.6<\/td>\n<\/tr>\n \n Human Fab2<\/a><\/td>\n Ab01680-10.7<\/td>\n<\/tr>\n \n Rabbit IgG<\/a><\/td>\n Ab01680-23.0<\/strong><\/td>\n<\/tr>\n \n Mouse IgG2b<\/a><\/td>\n Ab01680-3.0<\/strong><\/td>\n<\/tr>\n \n Mouse IgG2b Fc Silent\u2122<\/a><\/td>\n Ab01680-3.3<\/strong><\/td>\n<\/tr>\n \n Mouse IgM<\/a><\/td>\n Ab01680-21.0\u00a0<\/strong><\/td>\n<\/tr>\n \n Mouse Fab<\/a><\/td>\n Ab01680-1.6<\/strong><\/td>\n<\/tr>\n \n Mouse Fab2<\/a><\/td>\n Ab01680-1.7<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n \n\n
\n \u6297\u9ad4\u8ca8\u865f<\/td>\n \u6297\u9ad4\u540d\u7a31<\/td>\n Antibody Species<\/td>\n Isotype<\/td>\n LCFormat<\/td>\n Heavy Chain modification<\/td>\n Display_Amount<\/td>\n<\/tr>\n \n Ab01680-1.6<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 100 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-1.6-BS<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-1.6-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-1.7<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 100 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-1.7-BS<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-1.7-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG1<\/td>\n kappa<\/td>\n <\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG1<\/td>\n kappa<\/td>\n <\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-10.3<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG1<\/td>\n kappa<\/td>\n Fc Silent\u2122<\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.3-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG1<\/td>\n kappa<\/td>\n Fc Silent\u2122<\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-10.6<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 100 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.6-BS<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-10.6-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n Fab fragment<\/td>\n kappa<\/td>\n His-Tagged<\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.7<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 100 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-10.7-BS<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-10.7-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n F(ab)2<\/td>\n kappa<\/td>\n AbFab2\u2122 His-Tagged<\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-11.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG2<\/td>\n kappa<\/td>\n <\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-11.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG2<\/td>\n kappa<\/td>\n <\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-12.1<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG3<\/td>\n kappa<\/td>\n <\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-12.1-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgG3<\/td>\n kappa<\/td>\n <\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-15.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgM<\/td>\n kappa<\/td>\n <\/td>\n 50 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-15.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgM<\/td>\n kappa<\/td>\n <\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-16.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgA<\/td>\n kappa<\/td>\n <\/td>\n 50 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-16.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Human<\/td>\n IgA<\/td>\n kappa<\/td>\n <\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-21.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgM<\/td>\n kappa<\/td>\n <\/td>\n 50 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-21.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgM<\/td>\n kappa<\/td>\n <\/td>\n 500 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-23.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Rabbit<\/td>\n IgG<\/td>\n kappa<\/td>\n <\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-23.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Rabbit<\/td>\n IgG<\/td>\n kappa<\/td>\n <\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-3.0<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgG2b<\/td>\n kappa<\/td>\n <\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-3.0-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgG2b<\/td>\n kappa<\/td>\n <\/td>\n 1 mg<\/td>\n<\/tr>\n \n Ab01680-3.3<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgG2b<\/td>\n kappa<\/td>\n Fc Silent\u2122<\/td>\n 200 \u03bcg<\/td>\n<\/tr>\n \n Ab01680-3.3-BT<\/td>\n Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022]<\/td>\n Mouse<\/td>\n IgG2b<\/td>\n kappa<\/td>\n Fc Silent\u2122<\/td>\n 1 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n