{"id":25433,"date":"2020-06-18T12:33:03","date_gmt":"2020-06-18T04:33:03","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=25433"},"modified":"2024-02-01T17:12:00","modified_gmt":"2024-02-01T09:12:00","slug":"cox-2%e6%8a%91%e5%88%b6%e5%8a%91%e7%af%a9%e9%81%b8%e8%a9%a6%e5%8a%91%e7%9b%92-cox-2-inhibitor-screening-kit-fluorometric-%e8%b2%a8%e8%99%9fk547","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=25433","title":{"rendered":"COX-2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u76d2| COX-2 Inhibitor Screening Kit (Fluorometric) \u8ca8\u865fK547 (ab283401)"},"content":{"rendered":"

COX-1\u6291\u5236\u5291\u7be9\u9078K548\u00a0<\/a>\u00a0|\u00a0COX\u6d3b\u6027\u6e2c\u5b9a\u8a66\u5291<\/a>\u00a0|\u00a0COX-2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291<\/a>\u00a0|\u00a0\u74b0\u6c27\u5408\u91762\uff08COX-2\uff09ELISA\u8a66\u5291<\/a>\u00a0|\u00a0PTGS2 \/ COX-2\uff08\u4eba\u985e\uff09ELISA\u8a66\u5291<\/a><\/span><\/p>\n

COX-2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u76d2| \u8ca8\u865fK547 (ab283401)<\/a><\/span><\/p>\n

\"biovision\u00e5\u0095\u0086\u00e5\u0093\u0081\u00e6\u008f\u0092\u00e5\u009c\u0096\"<\/p>\n

COX-2 Inhibitor Screening Kit (Fluorometric)\u00a0<\/em><\/strong><\/p>\n

\u74b0\u6c27\u5408\u9176\uff08Cyclooxygenase , COX\uff09\uff0c\u4e5f\u7a31\u70ba\u524d\u5217\u817a\u7d20-\u5167\u904e\u6c27\u5316\u7269\u5408\u9176\uff08prostaglandin-endoperoxide synthase , PTGS\uff0cEC 1.14.99.1\uff09\uff0c\u662f\u4e00\u7a2e\u9176\uff0c\u8ca0\u8cac\u5f62\u6210\u7a31\u70ba\u524d\u5217\u817a\u7d20(prostanoids) \u7684\u91cd\u8981\u751f\u7269\u4ecb\u8cea\uff0c\u5305\u62ec\u524d\u5217\u817a\u7d20(prostaglandins)\uff0c\u524d\u5217\u817a\u7d20(prostacyclin)\u548c\u8840\u6813\u70f7(thromboxane)\u3002 COX\u662f\u5f9e\u82b1\u751f\u56db\u70ef\u9178(arachidonic acid)\u5230\u524d\u5217\u817a\u7d20(prostanoids)\u7684\u751f\u7269\u5408\u6210\u9014\u5f91\u4e2d\u7684\u4e2d\u5fc3\u9176\u3002\u6709\u5169\u7a2e\u5df2\u77e5\u7684\u540c\u529f\u9176(isoenzymes)\uff1aCOX-1\u548cCOX-2\u3002 COX-1\u5728\u8a31\u591a\u7d44\u7e54\u4e2d\u7d44\u6210\u6027\u8868\u9054\uff0c\u4e26\u4e14\u662f\u80c3\u7c98\u819c(gastric mucosa)\u548c\u814e\u81df(kidney)\u4e2d\u7684\u4e3b\u8981\u5f62\u5f0f\u3002\u5927\u591a\u6578\u7d30\u80de\u5728\u6b63\u5e38\u689d\u4ef6\u4e0b\u5747\u4e0d\u8868\u9054COX-2\uff0c\u4f46\u5728\u708e\u75c7\u904e\u7a0b\u4e2d\u767c\u73fe\u5176\u6c34\u5e73\u5347\u9ad8\u3002\u975e\u753e\u9ad4\u6297\u708e\u85e5\uff08non-steroidal anti-inflammatory drugs, NSAID\uff09\u5c0dCOX\u7684\u85e5\u7406\u6291\u5236\u4f5c\u7528\u53ef\u4ee5\u7de9\u89e3\u708e\u75c7\u548c\u75bc\u75db\u75c7\u72c0\u3002BioVision\u7684COX-2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u76d2\u63d0\u4f9b\u4e86\u4e00\u7a2e\u5feb\u901f\uff0c\u7c21\u55ae\uff0c\u9748\u654f\u548c\u53ef\u9760\u7684\u6e2c\u8a66\u65b9\u6cd5\uff0c\u9069\u7528\u65bc\u9ad8\u901a\u91cf\u7be9\u9078COX-2\u6291\u5236\u5291\u3002\u8a72\u6e2c\u5b9a\u6cd5\u57fa\u65bc\u5c0d\u524d\u5217\u817a\u7d20G2\uff08\u7531COX\u9176\u7522\u751f\u7684\u4e2d\u9593\u7522\u7269\uff09\u7684\u87a2\u5149\u6aa2\u6e2c\u3002<\/p>\n

\"\"<\/p>\n

COX2 Inhibitor Screening Kit<\/strong><\/div>\n
\n

Inhibition of COX2 Activity with Celecoxib. IC50<\/sub>\u00a0of Celecoxib was determined to be 0.45 \u03bcM.<\/p>\n<\/div>\n

\"K547\"<\/a><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Cat # +Size<\/th>\nK547-100 (ab283401)<\/td>\n<\/tr>\n
Size<\/th>\n100 assays<\/td>\n<\/tr>\n
Detection Method<\/th>\nFluorescence (Ex\/Em = 535\/587 nm)<\/td>\n<\/tr>\n
Applications<\/th>\nScreening\/studying\/characterizing COX-2 inhibitors.<\/td>\n<\/tr>\n
Features & Benefits<\/th>\n\u2022 Simple method to screen COX-2 inhibitors
\n\u2022 High-throughput
\n\u2022 Includes Inhibitor Control, Celecoxib<\/td>\n<\/tr>\n
Kit Components<\/th>\n\u2022 COX Assay Buffer
\n\u2022 COX Probe (in DMSO)
\n\u2022 COX Cofactor (in DMSO)
\n\u2022 Arachidonic Acid
\n\u2022 NaOH
\n\u2022 COX-2, human recombinant
\n\u2022 Celecoxib, COX-2 inhibitor (in DMSO)<\/td>\n<\/tr>\n
Storage Conditions<\/th>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/th>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/th>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u00e7\u009b\u00b8\u00e9\u0097\u009c\u00e8\u00a9\u00a6\u00e5\u008a\u0091\"<\/a><\/span><\/p>\n

\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a> | \u00a0FRAP\u6aa2\u6e2c<\/a> | \u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a> | Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a> | \u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a> | Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a> | \u8102\u8cea\u904e\u6c27\u5316\uff08<\/strong>MDA<\/strong>\uff09\u6e2c\u5b9a<\/strong><\/a> | <\/strong>\u652f\u93c8\u6c28\u57fa\u9178<\/strong><\/a> BCAA<\/u><\/strong>\u6aa2\u6e2c<\/u><\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Cat # +Size<\/strong><\/td>\nK547-100<\/td>\n<\/tr>\n
Size<\/strong><\/td>\n100 assays<\/td>\n<\/tr>\n
Detection Method<\/strong><\/td>\nFluorescence (Ex\/Em = 535\/587 nm)<\/td>\n<\/tr>\n
Applications<\/strong><\/td>\nScreening\/studying\/characterizing COX-2 inhibitors.<\/td>\n<\/tr>\n
Features & Benefits<\/strong><\/td>\n\u2022 Simple method to screen COX-2 inhibitors
\n\u2022 High-throughput
\n\u2022 Includes Inhibitor Control, Celecoxib<\/td>\n<\/tr>\n
Kit Components<\/strong><\/td>\n\u2022 COX Assay Buffer
\n\u2022 COX Probe (in DMSO)
\n\u2022 COX Cofactor (in DMSO)
\n\u2022 Arachidonic Acid
\n\u2022 NaOH
\n\u2022 COX-2, human recombinant
\n\u2022 Celecoxib, COX-2 inhibitor (in DMSO)<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 <\/strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a>\u00a0|\u00a0 <\/strong>Genereach<\/strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA<\/strong>\u5100\u5668<\/strong><\/a><\/p>\n

 <\/p>\n

\"\u00e7\u009b\u00b8\u00e9\u0097\u009c\u00e5\u0084\u0080\u00e5\u0099\u00a8\"<\/p>\n

\"CUBEE\u684c\u4e0a\u578b\u5c0f\u578b\u96e2\u5fc3\u6a5f\"<\/a>\"WPACO8000\"<\/a>\"MUPID-2<\/a>\"VORTEX\"<\/a>\"BIODROP-\u5be6\u9a57\u8a2d\u50993\"\"ELISA<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

COX-1\u6291\u5236\u5291\u7be9\u9078K548\u00a0\u00a0|\u00a0COX\u6d3b\u6027\u6e2c\u5b9a\u8a66\u5291\u00a0|\u00a0COX-2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u00a0|\u00a0\u74b0\u6c27\u5408\u91762\uff08COX- […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5261,5380,3],"tags":[1472],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25433"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25433"}],"version-history":[{"count":6,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25433\/revisions"}],"predecessor-version":[{"id":51295,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/25433\/revisions\/51295"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25433"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}