{"id":24114,"date":"2020-03-21T17:12:17","date_gmt":"2020-03-21T09:12:17","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=24114"},"modified":"2022-07-19T17:24:41","modified_gmt":"2022-07-19T09:24:41","slug":"egf-receptor-human-recombinant-%e8%b2%a8%e8%99%9f7135","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=24114","title":{"rendered":"EGF Receptor\u91cd\u7d44\u86cb\u767d | \u53ef\u6eb6\u6027(soluble)\u4ebaEGFR human recombinant \u8ca8\u865f7135"},"content":{"rendered":"

Home<\/strong><\/a> \u00a0 \u00a0<\/strong>Literature<\/strong><\/a>\u00a0 \u00a0<\/strong>Promotions<\/strong><\/a>\u00a0\u00a0<\/strong>Product Citations<\/strong><\/a><\/p>\n

EGF Receptor, human recombinant | <\/strong>\u8ca8\u865f<\/strong>7135<\/a><\/span><\/p>\n

\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong> EGF\u53d7\u9ad4\uff08EGF Receptor , EGFR\uff0cErbB1\uff09\u662f\u4e00\u7a2e\u8de8\u819c\u86cb\u767d(transmembrane protein)\uff0c\u53ef\u5728\u914d\u9ad4\u8a98\u5c0e\u7684\u6fc0\u6d3b\u5f8c\u767c\u63ee\u916a\u6c28\u9178\u6fc0\u9176\u6d3b\u6027(tyrosine kinase activity)\u3002 EGFR\u53ef\u4ee5\u901a\u904e\u7d50\u5408EGF\u6216\u81f3\u5c11\u516d\u500b\u5176\u4ed6\u7d50\u69cb\u76f8\u95dc\u7684\u86cb\u767d\u8cea\u914d\u9ad4\u4f86\u6fc0\u6d3b\uff0c\u5305\u62ecTGF\u03b1\uff0cHBEGF\uff0c\u03b2-\u7e96\u7dad\u7d20\uff08BTC\uff09\uff0c\u96d9\u8abf\u86cb\u767d\uff0c\u4e0a\u76ae\u8abf\u7bc0\u86cb\u767d\u548cEpigen\u3002\u6fc0\u6d3b\u5f8c\uff0cEGFR\u555f\u52d5\u4fe1\u865f\u50b3\u5c0e\u7d1a\u806f\uff0c\u5305\u62ec\u4e8c\u805a\u5316(dimerization) \u548c\u5167\u5728\u5316(internalization)\uff0c\u916a\u6c28\u9178\u78f7\u9178\u5316(tyrosine phosphorylation)\uff0c\u9776\u57fa\u56e0\u7684DNA\u5408\u6210(DNA synthesis)\u4ee5\u53ca\u6700\u7d42\u7d30\u80de\u589e\u6b96(cell proliferation)\u3002 EGFR\u4fe1\u865f\u50b3\u5c0e\u5728\u6b63\u5e38\u7d30\u80de\u7684\u751f\u9577(growth)\u548c\u5206\u5316(differentiation)\u4e2d\u8d77\u4f5c\u7528\uff0c\u4f46\u662fEGFR\u6d3b\u6027\u5347\u9ad8\u8207\u67d0\u4e9b\u764c\u75c7\u7684\u767c\u751f\u548c\u767c\u75c5\u6a5f\u5236\u76f8\u95dc\u3002\u91cd\u7d44\u53ef\u6eb6\u6027(soluble)\u4ebaEGFR\u662f\u4e00\u500b621\u500b\u6c28\u57fa\u9178\u7684\u7cd6\u86cb\u767d(amino acid glycoprotein)\uff0c\u5305\u542bEGFR\u7684\u80de\u5916\u57df (extracellular domain)\uff0c SDS-PAGE\u5206\u6790\u5206\u5b50\u91cf\u70ba97.5 kDa \u3002<\/p>\n

\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a> | \u00a0FRAP\u6aa2\u6e2c<\/a> | \u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a> | Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a> | \u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a> | Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a> | \u8102\u8cea\u904e\u6c27\u5316\uff08MDA\uff09\u6e2c\u5b9a<\/a> | <\/strong>\u652f\u93c8\u6c28\u57fa\u9178<\/a> BCAA<\/u><\/strong>\u6aa2\u6e2c<\/u><\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nErbB1<\/td>\n<\/tr>\n
Gene Symbol<\/strong><\/td>\nEGFR<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n1950<\/td>\n<\/tr>\n
Accession #<\/strong><\/td>\nP01133<\/td>\n<\/tr>\n
Source<\/strong><\/td>\nCHO cells<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nLyophilized powder<\/td>\n<\/tr>\n
Physical Form Description<\/strong><\/td>\nSterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.5.<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n97.5 kDa<\/td>\n<\/tr>\n
Purity by SDS-PAGE<\/strong><\/td>\n\u226595%<\/td>\n<\/tr>\n
Endotoxin Level<\/strong><\/td>\n< 0.1 ng\/\u03bcg of protein (<1EU\/\u03bcg).<\/td>\n<\/tr>\n
Reconstitution Instructions<\/strong><\/td>\nCentrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg\/ml. Do not vortex. This solution can be stored at 2-8\u00b0C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carri<\/td>\n<\/tr>\n
Amino Acid Sequence<\/strong><\/td>\nLEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE LPMRNLQEIL HGAVRFSNNP ALCNVESIQW RDIVSSDFLS NMSMDFQNHL GSCQKCDPSC PNGSCWGAGE ENCQKLTKII CAQQCSGRCR GKSPSDCCHN QCAAGCTGPR ESDCLVCRKF RD<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nCentrifuge the vial prior to opening.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 <\/strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a>\u00a0|\u00a0 <\/strong>Genereach<\/strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA<\/strong>\u5100\u5668<\/strong><\/a><\/p>\n

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Home \u00a0 \u00a0Literature\u00a0 \u00a0Promotions\u00a0\u00a0Product Citations EGF […]<\/p>\n","protected":false},"author":3,"featured_media":18514,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1615],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24114"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24114"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24114\/revisions"}],"predecessor-version":[{"id":24117,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24114\/revisions\/24117"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/18514"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24114"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}