{"id":24108,"date":"2020-03-21T16:05:52","date_gmt":"2020-03-21T08:05:52","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=24108"},"modified":"2023-05-03T16:19:44","modified_gmt":"2023-05-03T08:19:44","slug":"phorbol-12-myristate-13-acetate-pma-%e8%b2%a8%e8%99%9f1544-5","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=24108","title":{"rendered":"Phorbol-12-myristate 13-acetate (PMA) | \u8ca8\u865f1544-5 (abcam ab120297)"},"content":{"rendered":"<p><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" 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href=\"https:\/\/news.biovision.com\/e2t\/c\/*W3mnDG_7-SV65W2JlFGW6Fq-Q70\/*W70gFDC40_n_yW7F-pRS7sFJTh0\/5\/f18dQhb0Sjvl8YXNq0N8KJq44HyjJqVQZbhd7fR_5-N3hHhdwVMsQMVp3s9r7s5LskW5ls-Fh1SLfK3W8Xlz2h4dPRbgW8TntND4K0lj_W9bTNXY953-jPW5ZpycS57-ZBTW83C5JP1Z66s1W83KHrF7J39pBW2przrY6W3RDgMHd1gRBr0q_VYSX-57m_B1RW5c8d-S378ff7W6-dp-p6nTVy-W4X9CtZ742JJmVGnw382-q-0gW5tX5R26bMVrmW4Dct2k86k34NMDC8BVNF7msW1wG8Vr3gCzfGW2--nf06PzSJZW3hpLXd8qBKjTW5BY0zP6bYXbtW50R1h742tdGxW2HRbjS5cv3f4W42StRY3zX5s5W8JFnM98fvZPsMhzVNsnlkR-W3HR_B28csLSqW112pnt3lHLwcW5mfJnv8TgPJ4W49-8X848ck2TW3L_1k715k3HHW2GD9D74bnYzBW8tzCpX40ycBHVp6zJt3pZ82QW8VZ1rx436-65W83npcP5V9WFRW3f5_rb6sRBvlf2L_pdx04\"><strong>Promotions<\/strong><\/a><strong>\u00a0\u00a0<\/strong><a style=\"color: #0000ff;\" href=\"https:\/\/news.biovision.com\/e2t\/c\/*W3mnDG_7-SV65W2JlFGW6Fq-Q70\/*W8hFH5-9gD1MvW2S0Wsx10_ptq0\/5\/f18dQhb0Sjvc8XJblHN8KJq44HyjJqVQZbhd7fR_5-N3hHh9SXL0jYVp3s9r7s5LskW5ls-Fh1SLfK3W8Xlz2h4dPRbgW8T6VND2MVvLNW2M6BY84P1q-TW61SSZm7dDxTNW7mWsnX7dzcsSW51vDDW1bwwwgW5rC5Q63lPjQSW5ThdHg3s1XjFW51G0Bn4Zh8Y-W57-WqM3H_PtyW2DzCtR1zBkR0W3v6qd07V-rJ5W7870rg8cBhhnVkJfxB1tdchXW7qwh5X7MZ5pPW2kCctb8MJLLHVjQhxM52nx9pW5rnwVq6hTYTjW691Xkp82T4BsW6kfC678VSBpJW7sxsP37P1p1YW79ZZ1W6KNDhfW5_-MSx7jh1xGW6KZLTZ6t0v6nW92mpzn8Qjc56M6Q977b98XvW6w-c_q8Ph58-W594TqK1GmjdRW7n8SCm96KHTDW25-mc9236nNSN1T_KWnzFQyzW61lPZv269ZgJW8XldFG6HRkZmVbzvDX1J-PgcW96xdXG6J77M8W42Htk67D7HxjW1Dy_KC2-XXwXf37JpNz04\"><strong>Product Citations<\/strong><\/a><\/span><\/p>\n<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=24108\">Phorbol-12-myristate 13-acetate (PMA) <strong>| <\/strong><strong>\u8ca8\u865f<\/strong>1544-5 (abcam ab120297)<\/a><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/1\/5\/1544_1.gif\" alt=\"\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E5%8E%9F%E7%90%86%E4%BB%8B%E7%B4%B9-300x114.png\" alt=\"\u00e5\u008e\u009f\u00e7\u0090\u0086\u00e4\u00bb\u008b\u00e7\u00b4\u00b9\" width=\"93\" height=\"35\" \/> \u9019\u662f\u6700\u5e38\u7528\u7684\u4f5b\u6ce2\u916f (phorbol ester)\u3002\u5b83\u7d50\u5408\u4f75\u6fc0\u6d3b\u86cb\u767d\u6fc0\u9176C(activates protein kinase C)\uff0c\u5728\u7d30\u80de\u548c\u7d44\u7e54\u4e2d\u5f15\u8d77\u5ee3\u6cdb\u7684\u4f5c\u7528\uff0c\u4e26\u4e14\u662f\u4e00\u7a2e\u975e\u5e38\u6709\u6548\u7684\u5c0f\u9f20\u76ae\u819a\u816b\u7624\u555f\u52d5\u5b50(skin tumor promoter.)\u3002\u6291\u5236Fas\u6297\u539f\u8a98\u5c0e\u7684\u51cb\u4ea1(apoptosis induced)\uff0c\u4f46\u8a98\u5c0eHL-60\u65e9\u5e7c\u7c92\u7d30\u80de\u767d\u8840\u75c5\u7d30\u80de\u51cb\u4ea1\u3002 \u5f15\u7528\u6587\u737bLu et al., IL-17A, But Not IL-17F, Is Indispensable for Airway Vascular Remodeling Induced by Exaggerated Th17 Cell Responses in Prolonged Ovalbumin-Challenged Mice.\u00a0<a href=\"http:\/\/www.jimmunol.org\/content\/194\/8\/3557.abstract?maxtoshow=&amp;HITS=10&amp;hits=50&amp;RESULTFORMAT=1&amp;andorexacttitle=and&amp;andorexacttitleabs=and&amp;fulltext=biovision&amp;andorexactfulltext=and&amp;searchid=1&amp;FIRSTINDEX=0&amp;sortspec=match&amp;fdate=4\/1\/2015&amp;tdate=4\/30\/2015&amp;resourcetype=HWCIT\">J. Immunol.,\u00a0Apr 2015; 194: 3557 &#8211; 3566.<\/a><\/p>\n<p><span style=\"color: #008080;\"><a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=7010\"><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E7%9B%B8%E9%97%9C%E8%A9%A6%E5%8A%91-300x114.png\" alt=\"\u00e7\u009b\u00b8\u00e9\u0097\u009c\u00e8\u00a9\u00a6\u00e5\u008a\u0091\" width=\"100\" height=\"38\" \/>\u7a40\u80f1\u7518\u80bd\u904e\u6c27\u5316\u7269\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a>\u00a0| \u00a0<a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=18043\">FRAP\u6aa2\u6e2c<\/a>\u00a0|\u00a0<a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=8004\"><strong><u>\u7e3d\u81a0\u539f\u86cb\u767d\u5206\u6790<\/u><\/strong><\/a>\u00a0|\u00a0<a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=18876\">Dopamine\u591a\u5df4\u80fa\u6aa2\u6e2c<\/a>\u00a0|\u00a0<a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=6035\">\u4e09\u9178\u7518\u6cb9\u916f\u5206\u6790<\/a>\u00a0|\u00a0<a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=9470\">Cholesterol Efflux\u81bd\u56fa\u9187\u6392\u51fa\u87a2\u5149\u5206\u6790<\/a>\u00a0|\u00a0<strong><a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=14101\">\u8102\u8cea\u904e\u6c27\u5316\uff08MDA\uff09\u6e2c\u5b9a<\/a>\u00a0|\u00a0<\/strong><strong><a style=\"color: #008080;\" href=\"http:\/\/biopioneer.com.tw\/?p=15520\">\u652f\u93c8\u6c28\u57fa\u9178<\/a><u><span style=\"text-decoration: underline;\">\u00a0BCAA<\/span><\/u><\/strong><strong><u>\u6aa2\u6e2c<\/u><\/strong><\/span><\/p>\n<p><span style=\"color: #00ccff;\"><span style=\"color: #3366ff;\">\u5f15\u7528\u6587\u737b<\/span> <span style=\"color: #000000;\">Lu et al., IL-17A, But Not I<\/span><\/span>L-17F, Is Indispensable for Airway Vascular Remodeling Induced by Exaggerated Th17 Cell Responses in Prolonged Ovalbumin-Challenged Mice.\u00a0<a href=\"http:\/\/www.jimmunol.org\/content\/194\/8\/3557.abstract?maxtoshow=&amp;HITS=10&amp;hits=50&amp;RESULTFORMAT=1&amp;andorexacttitle=and&amp;andorexacttitleabs=and&amp;fulltext=biovision&amp;andorexactfulltext=and&amp;searchid=1&amp;FIRSTINDEX=0&amp;sortspec=match&amp;fdate=4\/1\/2015&amp;tdate=4\/30\/2015&amp;resourcetype=HWCIT\">J. Immunol.,\u00a0Apr 2015; 194: 3557 &#8211; 3566.<\/a><\/p>\n<table width=\"838\">\n<tbody>\n<tr>\n<td><strong>Cat # +Size<\/strong><\/td>\n<td>1544-5 (abcam ab120297)<\/td>\n<\/tr>\n<tr>\n<td><strong>Size<\/strong><\/td>\n<td>5 mg<\/td>\n<\/tr>\n<tr>\n<td><strong>Alternate Name<\/strong><\/td>\n<td>PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4\u03b2,9\u03b1,12\u03b2,13\u03b1,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>White solid<\/td>\n<\/tr>\n<tr>\n<td><strong>CAS #<\/strong><\/td>\n<td>16561-29-8<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Formula<\/strong><\/td>\n<td>C\u2083\u2086H\u2085\u2086O\u2088<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Weight<\/strong><\/td>\n<td>616.83<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity<\/strong><\/td>\n<td>&gt;99%<\/td>\n<\/tr>\n<tr>\n<td><strong>Solubility<\/strong><\/td>\n<td>DMSO or EtOH<\/td>\n<\/tr>\n<tr>\n<td><strong>SMILES<\/strong><\/td>\n<td>CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C<\/td>\n<\/tr>\n<tr>\n<td><strong>InChi<\/strong><\/td>\n<td>InChI=1S\/C36H56O8\/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40\/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3\/t24-,27+,28-,30-,32-,34-,35-,36-\/m1\/s1<\/td>\n<\/tr>\n<tr>\n<td><strong>InChi Key<\/strong><\/td>\n<td>PHEDXBVPIONUQT-RGYGYFBISA-N<\/td>\n<\/tr>\n<tr>\n<td><strong>PubChem CID<\/strong><\/td>\n<td><a href=\"http:\/\/pubchem.ncbi.nlm.nih.gov\/summary\/summary.cgi?cid=27924\">27924<\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>MDL Number<\/strong><\/td>\n<td>MFCD00036736<\/td>\n<\/tr>\n<tr>\n<td><strong>Handling<\/strong><\/td>\n<td>Protect from light<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>-20\u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shipping Conditions<\/strong><\/td>\n<td>Gel Pack<\/td>\n<\/tr>\n<tr>\n<td><strong>USAGE<\/strong><\/td>\n<td>For Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2021\/09\/Phorbol-12-myristate-13-acetate-PMA\u8ca8\u865f1544-5.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E5%8E%9F%E5%BB%A0%E6%93%8D%E4%BD%9C%E4%B8%8B%E8%BC%89-300x75.png\" alt=\"1544\" width=\"143\" height=\"37\" \/><\/a><\/p>\n<p><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=9187\"><strong>\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a><strong>\u00a0|\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=16198\"><strong>Finnpipette F3 <\/strong><strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a><strong>\u00a0| \u00a0<\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=17586\"><strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a><strong>\u00a0|\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=19075\"><strong>Genereach<\/strong><strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a><strong>\u00a0 |\u00a0\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=1120\"><strong>ELISA<\/strong><strong>\u5100\u5668<\/strong><\/a><\/span><\/p>\n<p><a href=\"http:\/\/biopioneer.com.tw\/?news=%e3%80%90%e7%92%b0%e5%a2%83%e8%a1%9b%e7%94%9f%e6%aa%a2%e6%b8%ac%e3%80%91kikkoman-smart-%e6%89%8b%e6%8c%81%e5%bc%8f-atp-%e5%be%ae%e7%94%9f%e7%89%a9%e5%86%b7%e5%85%89%e8%a8%88%e6%95%b8%e5%84%80 \"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E7%86%B1%E9%8A%B7%E5%95%86%E5%93%811-300x291.png\" alt=\"smart\" width=\"300\" height=\"291\" \/><\/a><a href=\"http:\/\/biopioneer.com.tw\/?news=%E3%80%90spectrum%E9%80%8F%E6%9E%90%E8%86%9C%E3%80%91%E9%80%8F%E6%9E%90%E5%8E%9F%E7%90%86%E5%88%86%E5%AD%90%E9%87%8F%E9%81%B8%E6%93%87%E9%80%8F%E6%9E%90%E6%96%B9%E5%BC%8F%E9%80%8F%E6%9E%90%E8%86%9C\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E7%86%B1%E9%8A%B7%E5%95%86%E5%93%812-300x291.png\" alt=\"Spectrumlab \" width=\"300\" height=\"291\" \/><\/a><a href=\"http:\/\/biopioneer.com.tw\/?news=%E3%80%90%E5%B0%BE%E5%B7%B4gdna%E8%90%83%E5%8F%96-tail-%E3%80%91viagen-directpcr-lysis-reagent-genotyping-%E8%B2%A8%E8%99%9F-102-t\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E7%86%B1%E9%8A%B7%E5%95%86%E5%93%813-300x291.png\" alt=\"\u71b1\u92b7\u5546\u54c13\" width=\"300\" height=\"291\" \/><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E7%86%B1%E9%8A%B7%E5%95%86%E5%93%814-300x291.png\" alt=\"0100-01\" width=\"300\" height=\"291\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Home \u00a0 \u00a0Literature\u00a0 \u00a0Promotions\u00a0\u00a0Product Citations Phor [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":5627,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1616],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24108"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24108"}],"version-history":[{"count":4,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24108\/revisions"}],"predecessor-version":[{"id":51037,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24108\/revisions\/51037"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/5627"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24108"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24108"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}