{"id":24090,"date":"2020-03-19T13:36:44","date_gmt":"2020-03-19T05:36:44","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=24090"},"modified":"2022-07-19T17:25:30","modified_gmt":"2022-07-19T09:25:30","slug":"amphotericin-b-usp%e5%85%a9%e6%80%a7%e9%bb%b4%e7%b4%a0-cas1397-89-3%e8%b2%a8%e8%99%9f2497","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=24090","title":{"rendered":"Amphotericin B, USP\u5169\u6027\u9ef4\u7d20 | CAS#1397-89-3\u8ca8\u865f2497"},"content":{"rendered":"

Amphotericin B, USP\u5169\u6027\u9ef4\u7d20 | \u00a0CAS#1397-89-3<\/strong>\u8ca8\u865f<\/strong>2497<\/a><\/span><\/p>\n

\"Amphotericin<\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u4f86\u81ea\u93c8\u9ef4\u83cc(Streptomyces) \u7684\u591a\u70ef\u6297\u771f\u83cc\u6297\u751f\u7d20(polyene antifungal antibiotic)\u3002\u5169\u6027\u9ef4\u7d20(Amphotericin B ) B\u9776\u5411\u591a\u7a2e\u654f\u611f\u771f\u83cc\uff0c\u5305\u62ec\u7d44\u7e54\u80de\u6f3f\u83cc(Histoplasma)\uff0c\u7403\u87f2(Coccidioides)\u548c\u96b1\u7403\u83cc(Cryptococcus species)\u3002\u5169\u6027\u9ef4\u7d20B(Amphotericin B)\u9776\u5411\u771f\u83cc\u7d30\u80de\u819c\u4e2d\u7684\u9ea5\u89d2\u56fa\u9187(ergosterol)\u4e26\u589e\u52a0\u901a\u900f\u6027(permeability) \u3002\u7d30\u80de\u819c\u7684\u9019\u7a2e\u6539\u8b8a\u5c0d\u771f\u83cc\u6709\u6bd2\u4e26\u5c0e\u81f4\u6b7b\u4ea1\u3002\u53ef\u4ee5\u5728\u591a\u7a2e\u985e\u578b\u7684\u9694\u96e2\u4ecb\u8cea\u4e2d\u7528\u4f5c\u9078\u64c7\u5291\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nFungizone<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nYellow or orange powder<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n1397-89-3<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2084\u2087H\u2087\u2083NO\u2081\u2087<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n924.08<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n>750 \u00b5g\/mg<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMF (~2-4 mg\/ml) or DMSO (~30-40 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCC1C=CC=CC=CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C47H73NO17\/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56\/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)\/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+\/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+\/m0\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nAPKFDSVGJQXUKY-INPOYWNPSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n5280965<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00877763<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Amphotericin B, USP\u5169\u6027\u9ef4\u7d20 | \u00a0CAS#1397-89-3\u8ca8\u865f2497 \u7522\u54c1\u4ecb\u7d39: \u4f86\u81ea […]<\/p>\n","protected":false},"author":3,"featured_media":24091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1620,1621],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24090"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24090"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24090\/revisions"}],"predecessor-version":[{"id":45147,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/24090\/revisions\/45147"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/24091"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24090"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}