{"id":23938,"date":"2020-03-08T15:30:58","date_gmt":"2020-03-08T07:30:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=23938"},"modified":"2022-07-19T17:29:16","modified_gmt":"2022-07-19T09:29:16","slug":"%e8%a1%80%e7%ae%a1%e7%b7%8a%e5%bc%b5%e7%b4%a0ii%e8%bd%89%e6%8f%9b%e9%85%b6%ef%bc%88ace2%ef%bc%89%e6%8a%91%e5%88%b6%e5%8a%91%e7%af%a9%e9%81%b8-angiotensin-ii-converting-enzyme-inhibitor-screening-kit","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=23938","title":{"rendered":"\u8840\u7ba1\u7dca\u5f35\u7d20II\u8f49\u63db\u9176\uff08ACE2\uff09\u6291\u5236\u5291\u7be9\u9078 | Angiotensin II Converting Enzyme Inhibitor Screening Kit\u8ca8\u865fK310-100"},"content":{"rendered":"

\u51a0\u72c0\u75c5\u6bd2(Coronaviruses)\u662f\u4e00\u7a2e\u5ee3\u6cdb\u5b58\u5728\u65bc\u591a\u7a2e\u52d5\u7269\u9ad4\u7684\u75c5\u539f\u9ad4\uff0c\u70ba\u4e00\u7a2e\u55ae\u93c8\u6b63\u80a1\uff08single-stranded, positive-sense RNA viruses\uff09\u7684 RNA \u75c5\u6bd2\uff0c\u5177\u6709\u5916\u6bbc\u86cb\u767d(capsid)\u53ca\u5916\u5957\u819c\uff08envelope\uff09\uff0c\u57fa\u56e0\u7d44\u5927\u5c0f\u7d04\u70ba 26-32\u5343\u9e7c\u57fa\u5c0d\uff08kilo base pair\uff09\uff0c\u662f\u6240\u6709RNA\u75c5\u6bd2\u4e2d\u6700\u5927\u7684\u75c5\u6bd2\u3002\u51a0\u72c0\u75c5\u6bd2\uff08coronavirus\uff09\u611f\u67d3\u4eba\u9ad4\u6703\u5f15\u767c\u547c\u5438\u9053\u75be\u75c5\uff0c\u5176\u4e2dSARS-CoV\u3001MERS-CoV\u53ca2019-nCoV\u4e09\u7a2e\u53ef\u9020\u6210\u81f4\u547d\u7684\u80ba\u708e\u3002\u5176\u4e2d2019-nCoV\u5f15\u8d77\u7684\u56b4\u91cd\u7279\u6b8a\u50b3\u67d3\u6027\u80ba\u708e\uff0c\u6210\u70ba\u570b\u969b\u95dc\u6ce8\u7684\u7126\u9ede\u3002\u8a72\u75c5\u6bd2\u6bd4SARS-CoV\u548cMERS-CoV\u7684\u7e3d\u548c\u81f4\u547d\u5f97\u591a\uff0c\u4ee5\u524d\u7a31\u70baCOVID-19\uff0c\u5f8c\u88ab\u547d\u540d\u70baSARS-CoV-2\u3002\u7531\u65bc\u95dc\u65bcSARS-CoV-2\u86cb\u767d\u5728\u75c5\u6bd2\u767c\u75c5\u6a5f\u7406\u548c\u5fa9\u5236\u4e2d\u4f5c\u7528\u7684\u4fe1\u606f\u6709\u9650\uff0c\u56e0\u6b64\u6c92\u6709\u5f88\u591a\u53ef\u7528\u7684\u6cbb\u7642\u65b9\u6cd5\u3002\u5e02\u5834\u4e0a\u53ef\u7528\u7684\u7814\u7a76\u5de5\u5177\u6709\u9650\u3002 BioVision\u63a8\u51fa\u51a0\u72c0\u75c5\u6bd2\u6297\u9ad4\uff0c\u86cb\u767d\u8cea\uff0c\u8a66\u5291\u76d2\u548c\u6297\u75c5\u6bd2\u5291\uff0c\u9019\u662f\u51a0\u72c0\u75c5\u6bd2\u7814\u7a76\u5e02\u5834\u4e0a\u7684\u7b2c\u4e00\u6b3e\u7522\u54c1\u3002\u9019\u4e9b\u7814\u7a76\u7522\u54c1\u53ef\u4ee5\u6aa2\u6e2cSARS-CoV-2\uff0cSARS\u548cMERS\u51a0\u72c0\u75c5\u6bd2\u3002<\/p>\n

\u8840\u7ba1\u7dca\u5f35\u7d20II\u8f49\u63db\u9176\uff08ACE2\uff09\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u76d2 | <\/strong>\u8ca8\u865f<\/strong>K310-100<\/a><\/span><\/p>\n

Angiotensin II Converting Enzyme (ACE2) Inhibitor Screening Kit<\/p>\n

\"\"<\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u8840\u7ba1\u7dca\u5f35\u7d20II\u8f49\u63db\u9176\uff08Angiotensin II converting enzyme , ACE2\uff0cEC 3.4.17.23\uff09\u662f\u4e00\u7a2e\u7fa7\u80bd\u9176(carboxypeptidase)\uff0c\u662f\u814e\u7d20-\u8840\u7ba1\u7dca\u5f35\u7d20\u7cfb\u7d71\uff08renin-angiotensin system , RAS\uff09\u7684\u4e00\u90e8\u5206\uff0c\u8a72\u7cfb\u7d71\u901a\u904e\u88c2\u89e3\u8840\u7ba1\u7dca\u5f35\u7d20II\u7684C\u7aef\u4e8c\u80bd\u5c07\u5176\u8f49\u5316\u70ba\u8840\u7ba1\u7dca\u5f35\u7d20\u4f86\u63a7\u5236\u8840\u58d3(blood pressure)\u3002 \u5207\u5272\u8840\u7ba1\u7dca\u5f35\u7d20I\u7522\u751f\u672a\u77e5\u529f\u80fd\u7684Ang 1-9\u3002 ACE2\u662f\u4eba\u985e\u51a0\u72c0\u75c5\u6bd2\uff08human coronaviruses, \u5982SARS\u548cHCoV-NL63\uff09\u7684\u53d7\u9ad4\u3002\u5b83\u5728\u5fc3\u81df\u548c\u814e\u81df\u7684\u8840\u7ba1\u5167\u76ae\u7d30\u80de(vascular endothelial cells)\u4e0a\u8868\u9054\u3002 ACE2\u6291\u5236\u5291\u53ef\u4ee5\u901a\u904e\u6539\u8b8a\u8840\u7ba1\u901a\u900f\u6027\u4f86\u8abf\u7bc0\u9ad8\u8840\u58d3\u3002\u7be9\u9078\u5c0f\u5206\u5b50\u548c\u80bd\u6291\u5236\u5291\u4e5f\u53ef\u80fd\u6709\u52a9\u65bc\u5c0b\u627e\u6cbb\u7642\u51a0\u72c0\u75c5\u6bd2\u4ecb\u5c0e\u7684\u611f\u67d3\u7684\u65b9\u6cd5\u3002 BioVision\u7684ACE2\u6291\u5236\u5291\u7be9\u9078\u8a66\u5291\u76d2\u53ef\u7528\u65bc\u7be9\u9078ACE2\u6d3b\u6027\u7684\u5f37\u6548\u6291\u5236\u5291\uff0c\u5b83\u5229\u7528\u6d3b\u6027ACE2\u7684\u80fd\u529b\u88c2\u89e3\u57fa\u65bcMCA\u7684\u5408\u6210\u80bd\u5e95\u7269\uff0c\u91cb\u653e\u51fa\u6e38\u96e2\u7684\u87a2\u5149\u5718\u3002\u91cb\u653e\u7684MCA\u53ef\u4ee5\u4f7f\u7528\u87a2\u5149\u9176\u6a19\u5100\u8f15\u9b06\u5b9a\u91cf\u3002\u5728ACE2\u7279\u7570\u6027\u6291\u5236\u5291\u7684\u5b58\u5728\u4e0b\uff0c\u8a72\u9176\u5931\u53bb\u5176\u80bd\u9176\u6d3b\u6027\uff0c\u9019\u5c0e\u81f4\u87a2\u5149\u5f37\u5ea6\u964d\u4f4e\u3002\u8a72\u6e2c\u5b9a\u8a66\u5291\u76d2\u975e\u5e38\u7c21\u55ae\uff0c\u53ef\u7528\u65bc\u4ee5\u9ad8\u901a\u91cf\u5f62\u5f0f\u9451\u5b9a\u548c\u8868\u5fb5ACE2\u6291\u5236\u5291\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Cat # +Size<\/strong><\/td>\nK310-100<\/td>\n<\/tr>\n
Size<\/strong><\/td>\n100 assays<\/td>\n<\/tr>\n
Detection Method<\/strong><\/td>\nFluorescence (Ex\/Em = 320\/420 nm)<\/td>\n<\/tr>\n
Applications<\/strong><\/td>\nScreening\/characterizing\/studying ACE2 inhibitors\/activators<\/td>\n<\/tr>\n
Features & Benefits<\/strong><\/td>\n\u2022 Simple and reliable test to screen ACE2 inhibitors\/activators
\n\u2022 High-throughput compatible
\n\u2022 Includes Inhibitor Control<\/td>\n<\/tr>\n
Kit Components<\/strong><\/td>\n\u2022 ACE2 Assay Buffer
\n\u2022 ACE2 Dilution Buffer
\n\u2022 ACE2 Enzyme
\n\u2022 ACE2 Substrate
\n\u2022 ACE2 Inhibitor (0.5 mM)<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Category<\/strong><\/td>\nProduct Name<\/strong><\/td>\nCat. No.<\/strong><\/td>\nSize<\/strong><\/td>\n<\/tr>\n
\n

 <\/p>\n

Antibodies<\/td>\n

Anti-Canine Coronavirus (Capture) Antibody<\/td>\nA2069<\/strong><\/a><\/td>\n100 \u00b5g<\/td>\n<\/tr>\n
Anti-Canine Coronavirus (Self-pair) Antibody<\/td>\nA2068<\/strong><\/a><\/td>\n100 \u00b5g<\/td>\n<\/tr>\n
Anti-Canine Coronavirus Polyclonal Antibody<\/td>\nA2070<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-MERS & SARS-CoV NP Mouse IgG1 Antibody<\/td>\nA2063<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-MERS-CoV S1 Mouse IgG1 Antibody<\/td>\nA2065<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-MERS-CoV S1 Mouse IgG2a Antibody<\/td>\nA2067<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-SARS-CoV NP Mouse IgG1 Antibody<\/td>\nA2066<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-SARS-CoV NP Mouse IgG2b Antibody<\/td>\nA2064<\/strong><\/a><\/td>\n100 \u03bcg<\/td>\n<\/tr>\n
Anti-SARS-CoV-2 Antibody<\/td>\nA2061\u00a0<\/strong><\/a><\/td>\n50 \u00b5g<\/td>\n<\/tr>\n
Anti-SARS-CoV-2 Antibody (Clone# 6F10)<\/td>\nA2060<\/strong><\/a><\/td>\n50 \u00b5g<\/td>\n<\/tr>\n
Anti-viral Agent<\/td>\nRemdesivir<\/td>\nB2997<\/strong><\/a><\/td>\n500 \u00b5g, 1 mg<\/td>\n<\/tr>\n
Kit<\/td>\nCoronavirus (SARS-CoV-2) PCR Detection Kit<\/td>\nK1460<\/strong><\/a><\/td>\n100 Rxns<\/td>\n<\/tr>\n
\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 
\nRecombinant Proteins<\/td>\n

Envelope Protein (SARS-CoV ENV;1-76)<\/td>\nP1503<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Matrix Protein (SARS-CoV; 182-216)<\/td>\nP1504<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Membrane Protein (SARS-CoV, His tag)<\/td>\nP1505<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (CoV-NP 229E)<\/td>\nP1506<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (CoV-NP-NL63)<\/td>\nP1507<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (SARS-CoV)<\/td>\nP1509<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (SARS-CoV; 1-49)<\/td>\nP1510<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (SARS-CoV; 1-49, 192-220)<\/td>\nP1511<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (SARS-CoV; 340-390)<\/td>\nP1508<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Nucleoprotein (SARS-CoV; 340-390)<\/td>\nP1512<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (MERS-CoV S1; 18-725)<\/td>\nP1513<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (MERS-CoV S1; 56-295)<\/td>\nP1514<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S, His tag)<\/td>\nP1520<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S1; 12-53, 90-115, 171-203)<\/td>\nP1515<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S1; His tag)<\/td>\nP1516<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S2)<\/td>\nP1519<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S2; 408-470, 540-573)<\/td>\nP1518<\/strong><\/a><\/td>\n10 \u03bcg, 50 \u03bcg<\/td>\n<\/tr>\n
Spike Protein (SARS-CoV S2; 408-470, 540-573, His Tag)<\/td>\nP1517<\/strong><\/a><\/td>\n10 \u03bcg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u51a0\u72c0\u75c5\u6bd2(Coronaviruses)\u662f\u4e00\u7a2e\u5ee3\u6cdb\u5b58\u5728\u65bc\u591a\u7a2e\u52d5\u7269\u9ad4\u7684\u75c5\u539f\u9ad4\uff0c\u70ba\u4e00\u7a2e\u55ae\u93c8\u6b63\u80a1\uff08single-str […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1658],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23938"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23938"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23938\/revisions"}],"predecessor-version":[{"id":25594,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23938\/revisions\/25594"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23938"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23938"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23938"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}