{"id":23517,"date":"2020-02-07T10:39:58","date_gmt":"2020-02-07T02:39:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=23517"},"modified":"2022-07-19T17:34:46","modified_gmt":"2022-07-19T09:34:46","slug":"%e6%8a%97%e7%98%a7%e7%96%be%e8%97%a5%e7%89%a9%e4%ba%8c%e7%a3%b7%e9%85%b8%e6%b0%af%e5%a5%8e-chloroquine-diphosphate-cas50-63-5-%e8%b2%a8%e8%99%9f1825-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=23517","title":{"rendered":"\u6297\u7627\u75be\u85e5\u7269\u4e8c\u78f7\u9178\u6c2f\u594e | Chloroquine Diphosphate CAS#50-63-5 \u8ca8\u865f1825-100"},"content":{"rendered":"

Chloroquine Diphosphate\u4e8c\u78f7\u9178\u6c2f\u594e | <\/strong>CAS#50-63-5 \u8ca8\u865f1825-100<\/a><\/span><\/p>\n

An autophagy inhibitor<\/p>\n

\u7522\u54c1\u4ecb\u7d39: An antimalarial drug. Inhibits autophagy of glioma cells via a mechanism distinct from that of 3-Methyladenine. \u6297\u7627\u75be\u85e5\u7269\u6c2f\u594e\uff0c\u901a\u904e\u4e0d\u540c\u65bc3-\u7532\u57fa\u817a\u560c\u5464(3-Methyladenine)\u7684\u6a5f\u5236\u6291\u5236\u795e\u7d93\u81a0\u8cea\u7624\u7d30\u80de(glioma cells)\u7684\u81ea\u566c(autophagy)\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nN\u2074-(7-Chloro-4-quinolinyl)-N\u00b9,N\u00b9-dimethyl-1,4-pentanediamine diphosphate salt<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n50-63-5<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2088H\u2082\u2086ClN\u2083\u00b72H\u2083PO\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n515.86<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598% by TLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nH\u2082O (100 mM)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C18H26ClN3.2H3O4P\/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4\/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nQKICWELGRMTQCR-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n64927<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00069852<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nRT<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Chloroquine Diphosphate\u4e8c\u78f7\u9178\u6c2f\u594e | CAS#50-63-5 \u8ca8\u865f1825-100 A […]<\/p>\n","protected":false},"author":3,"featured_media":23518,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[451],"tags":[1701],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23517"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23517"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23517\/revisions"}],"predecessor-version":[{"id":23519,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23517\/revisions\/23519"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/23518"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23517"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23517"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23517"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}