{"id":23188,"date":"2020-01-30T15:08:51","date_gmt":"2020-01-30T07:08:51","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=23188"},"modified":"2022-07-19T17:36:45","modified_gmt":"2022-07-19T09:36:45","slug":"irs-1%e6%8a%97%e9%ab%94-irs-1-antibody%e8%b2%a8%e8%99%9f3424-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=23188","title":{"rendered":"IRS-1\u6297\u9ad4 | IRS-1 Antibody\u8ca8\u865f3424-100"},"content":{"rendered":"

IRS-1\u6297\u9ad4 | <\/strong>\u8ca8\u865f<\/strong>3424-100<\/a><\/span><\/p>\n

IRS-1 Antibody<\/em><\/strong><\/p>\n

\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong> IRS-1\uff08\u80f0\u5cf6\u7d20\u53d7\u9ad4\u5e95\u72691\uff09\u78f7\u9178\u5316\u97ff\u61c9\u80f0\u5cf6\u7d20(insulin)\u523a\u6fc0\u7d30\u80de\u3002 \u914d\u9ad4\u8a98\u5c0e(ligand-induced)\u7684\u78f7\u9178\u5316\u5f8c\uff0cIRS-1\u7acb\u5373\u8207\u4e00\u7cfb\u5217\u542bSH2\u57df\u7684\u4fe1\u865f\u50b3\u5c0e\u4e2d\u9593\u9ad4\uff08\u4f8b\u5982PI3-\u6fc0\u9176\uff0cGRB2\uff0cSyp\u548cNck\uff09\u7de0\u5408\u3002 \u8207\u6fc0\u6d3b\u7684IRS-1\u7d50\u5408\u7684\u542bSH2\u7684\u86cb\u767d\u8cea\u5728\u7d50\u69cb\u548c\u529f\u80fd\u4e0a\u7684\u591a\u6a23\u6027\u6c34\u5e73\u5c0d\u80f0\u5cf6\u7d20\u7684\u53cd\u61c9\u6027\u5f88\u91cd\u8981\u3002 IRS\u78f7\u9178\u5316(IRS phosphorylation)\u901a\u904e\u5141\u8a31\u8461\u8404\u7cd6\u651d\u53d6(glucose uptake)\uff0c\u7cd6\u539f\u5408\u6210(glycogen synthesis)\u548c\u4fc3\u6709\u7d72\u5206\u88c2\u6d3b\u6027(mitogenic activity)\u4f86\u5f15\u767c\u80f0\u5cf6\u7d20\u751f\u9577\u56e0\u5b50\u548c\u80f0\u5cf6\u7d20\u7684\u751f\u9577\u548c\u4ee3\u8b1d\u4f5c\u7528\u3002 IRS-1\u5728170\u81f3185 kDa\u4e4b\u9593\u9077\u79fb\uff0c\u4e26\u5728\u5927\u591a\u6578\u7d30\u80de\u985e\u578b\u4e2d\u8868\u9054\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Cat # +Size<\/strong><\/td>\n3424-100<\/td>\n<\/tr>\n
Size<\/strong><\/td>\n100 \u00b5g<\/td>\n<\/tr>\n
Antibody Target<\/strong><\/td>\nIRS-1<\/td>\n<\/tr>\n
Host<\/strong><\/td>\nRabbit<\/td>\n<\/tr>\n
Antibody Type<\/strong><\/td>\nPolyclonal<\/td>\n<\/tr>\n
Isotype<\/strong><\/td>\nRabbit IgG<\/td>\n<\/tr>\n
Immunogen<\/strong><\/td>\nSynthetic peptide mapping to the C-terminus of human IRS-1<\/td>\n<\/tr>\n
Accession #<\/strong><\/td>\nP35568<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n3667<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nColorless liquid<\/td>\n<\/tr>\n
Concentration<\/strong><\/td>\n0.5 mg\/ml<\/td>\n<\/tr>\n
Formulation<\/strong><\/td>\n100 \u00b5g (0.5 mg\/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.<\/td>\n<\/tr>\n
Purification<\/strong><\/td>\nAffinity purified<\/td>\n<\/tr>\n
Species Reactivity<\/strong><\/td>\nHuman, mouse, rat<\/td>\n<\/tr>\n
Application<\/strong><\/td>\nWestern blot, Immunohistochemistry<\/td>\n<\/tr>\n
Application & Usage<\/strong><\/td>\nWestern blotting (0.5-4 \u00b5g\/ml). However, the optimal conditions should be determined individually<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nThe antibody solution should be gently mixed before use.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20 \u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 <\/strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a>\u00a0|\u00a0 <\/strong>Genereach<\/strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA<\/strong>\u5100\u5668<\/strong><\/a><\/span><\/p>\n

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\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

IRS-1\u6297\u9ad4 | \u8ca8\u865f3424-100 IRS-1 Antibody \u7522\u54c1\u63cf\u8ff0\uff1a IRS-1\uff08\u80f0\u5cf6\u7d20\u53d7\u9ad4\u5e95\u7269 […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[1714],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23188"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23188"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23188\/revisions"}],"predecessor-version":[{"id":23193,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23188\/revisions\/23193"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23188"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23188"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23188"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}