{"id":22890,"date":"2020-01-07T17:21:32","date_gmt":"2020-01-07T09:21:32","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=22890"},"modified":"2022-07-19T17:43:27","modified_gmt":"2022-07-19T09:43:27","slug":"%e6%b0%af%e4%b8%99%e5%97%aa-chlorpromazine-a-dopamine-receptor-antagonist-cas-69-09-0%e8%b2%a8%e8%99%9fb1992","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=22890","title":{"rendered":"\u6c2f\u4e19\u55ea (Chlorpromazine) | A dopamine receptor antagonist CAS #69-09-0\u8ca8\u865fB1992"},"content":{"rendered":"

\u6c2f\u4e19\u55ea (Chlorpromazine) |<\/strong> A dopamine receptor antagonist<\/em><\/strong> <\/a><\/span>\u00a0<\/strong>CAS #<\/strong>69-09-0\u8ca8\u865f<\/strong>B1992<\/p>\n

A dopamine receptor antagonist<\/em><\/strong><\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u6c2f\u4e19\u55ea (Chlorpromazine) \u662f\u4e00\u7a2e\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291(dopamine receptor antagonist)\u3002\u6e1b\u5c11\u795e\u7d93\u905e\u8cea(neurotransmitter binding)\u7684\u7d50\u5408\u3002\u6291\u5236\u5c0f\u9f20\u8166\u7d30\u80de\u6eb6\u81a0\u4e2d\u4e00\u6c27\u5316\u6c2e(nitric oxide synthesis)\u7684\u5408\u6210\u3002\u4e5f\u53ef\u4f5c\u70banAChR\uff0c\u7d44\u80fa(histamine)\u548c5-HT\u53d7\u9ad4\u7684\u62ee\u6297\u5291\u3002\u5c0d\u591a\u7a2e\u816b\u7624\u7d30\u80de\u7cfb\u986f\u793a\u51fa\u751f\u9577\u6291\u5236\u4f5c\u7528\u3002\u8868\u73fe\u51fa\u6297\u7cbe\u795e\u75c5\u6d3b\u6027(antipsychotic activity)\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, monohydrochloride; CPZ; Thorazine; Promacid<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n69-09-0<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2087H\u2081\u2089ClN\u2082S \u2022 HCl<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n355.32<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598%<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (~ 30 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C17H19ClN2S.ClH\/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;\/h3-4,6-9,12H,5,10-11H2,1-2H3;1H<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nFBSMERQALIEGJT-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n6240<\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00012654<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\nRT<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nRT<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

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