{"id":21898,"date":"2019-09-03T17:18:14","date_gmt":"2019-09-03T09:18:14","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=21898"},"modified":"2022-07-20T10:49:12","modified_gmt":"2022-07-20T02:49:12","slug":"anti-der-p-2-h10-rabbit-igg-kappa","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=21898","title":{"rendered":"Anti-Der p 2 [H10], Rabbit IgG, Kappa|absoluteantibody\u8ca8\u865fAb01250-23.0"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=21898\">Anti-Der p 2 [H10], Rabbit IgG, Kappa\u6297\u9ad4 |\u8ca8\u865fAb01250-23.0<\/a><\/span><\/p>\n<p><strong>UniProt Accession Number of Target Protein:<\/strong>\u00a0P49278<\/p>\n<p><strong>Alternative Name(s) of Target:<\/strong>\u00a0Mite group 2 allergen Der p 2; Allergen Der p II; DPX<br \/>\n<strong>Immunogen:<\/strong>\u00a0The antibody was generated by immunising mice with Der p 2.<\/p>\n<p><strong>Specificity:<\/strong>\u00a0H10 binds a distinct epitope to clones H3 and H5.<\/p>\n<p><strong>Application Notes:<\/strong>\u00a0The VH and VL sequences of H10 were used to generate a chimeric recombinant IgE antibody. The binding of chimeric H10 to Der p 2 was confirmed using SPR, with a Kd value of 0.0358 nM. SPR also showed it binds distinct epitopes to clones H3 and H5.<\/p>\n<p><strong>Antibody first published in:<\/strong>\u00a0Christensen et al. Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge J Allergy Clin Immunol.\u00a02008 Aug;122(2):298-304.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18572230\" target=\"_blank\">PMID:18572230<\/a><br \/>\n<strong>Note on publication:<\/strong>\u00a0Descibes the original production of the antibody and its characterisation through SPR.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anti-Der p 2 [H10], Rabbit IgG, Kappa\u6297\u9ad4 |\u8ca8\u865fAb01250-23.0 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3519,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136,3],"tags":[1945,1946,1381],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21898"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21898"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21898\/revisions"}],"predecessor-version":[{"id":21900,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21898\/revisions\/21900"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/3519"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21898"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21898"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}