{"id":21359,"date":"2019-07-17T15:20:14","date_gmt":"2019-07-17T07:20:14","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=21359"},"modified":"2022-07-20T11:08:04","modified_gmt":"2022-07-20T03:08:04","slug":"sb-203580%e6%8a%91%e5%88%b6%e5%8a%91-cas152121-47-6%e8%b2%a8%e8%99%9f1712-5","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=21359","title":{"rendered":"SB 203580\u6291\u5236\u5291 | CAS#152121-47-6\u8ca8\u865f1712-5"},"content":{"rendered":"

SB 203580<\/em>\u6291\u5236\u5291 | CAS#152121-47-6\u8ca8\u865f1712-5<\/a><\/span><\/p>\n

SB 203580-A MAP Kinase inhibitor<\/p>\n

\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>SB 203580 \u70baA MAP Kinase inhibitor \uff0c\u5177\u7d30\u80de\u6ef2\u900f\u6027(Cell-permeable)\u3002 p38\u4fc3\u5206\u88c2\u539f\u6d3b\u5316\u86cb\u767d\u6fc0\u9176\uff08MAP\u6fc0\u9176\uff09\u7684\u9078\u64c7\u6027\u6291\u5236\u5291\uff08\u5c0d\u65bcSAPK2a \/ p38\u548cSAPK2b \/p38\u03b22\uff0cIC 50\u503c\u5206\u5225\u70ba50\u548c500nM\uff09\u3002 \u986f\u793a\u51fa\u6bd4LCK\uff0cGSK3\u03b2\u548cPKB\u03b1\u9ad8100-500\u500d\u7684\u9078\u64c7\u6027\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n152121-47-6<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2081H\u2081\u2086FN\u2083OS<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n377.43<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226599% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (>50 mg\/ml) or warm ethanol (12 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C21H16FN3OS\/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15\/h2-13H,1H3,(H,24,25)<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nCDMGBJANTYXAIV-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n176155<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00922198<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from air and light<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

SB 203580\u6291\u5236\u5291 | CAS#152121-47-6\u8ca8\u865f1712-5 SB 203580-A MAP […]<\/p>\n","protected":false},"author":3,"featured_media":21360,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[2061],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21359"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21359"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21359\/revisions"}],"predecessor-version":[{"id":21361,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/21359\/revisions\/21361"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/21360"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21359"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21359"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}