{"id":20857,"date":"2019-06-11T14:52:07","date_gmt":"2019-06-11T06:52:07","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=20857"},"modified":"2022-07-20T11:42:19","modified_gmt":"2022-07-20T03:42:19","slug":"rotenone%e6%ae%ba%e8%9f%b2%e5%8a%91-cas-83-79-4%e8%b2%a8%e8%99%9f2248","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=20857","title":{"rendered":"Rotenone\u6bba\u87f2\u5291 | CAS #83-79-4\u8ca8\u865f2248"},"content":{"rendered":"

Rotenone<\/strong>\u6bba\u87f2\u5291 | <\/strong>\u8ca8\u865f<\/strong>2248 <\/strong><\/a><\/span><\/p>\n

A mitochondrial electron transport chain inhibitor<\/em><\/strong><\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u4e00\u7a2e\u5ee3\u8b5c\u6027\u6bba\u87f2\u5291 (insecticide) \uff0c\u5177\u6709\u7d30\u80de\u6ef2\u900f\u6027 (cell-permeable) \u548c\u8166\u900f\u6027\u3002\u4f5c\u70ba\u7dda\u7c92\u9ad4\u96fb\u5b50\u50b3\u905e\u93c8\u6291\u5236\u5291 (mitochondrial electron transport chain inhibitor)\uff08\u5728\u8907\u5408\u7269I\u4e2dIC 50 =1.7-2.2\u03bcM\uff09\u3002\u901a\u904e\u5fc3\u808c\u808c\u6f3f\u7db2 (cardiac sarcoplasmic reticulum) \u6291\u5236NADH\u6c27\u5316\uff08IC 50 = 3.4nM\uff09\u3002\u795e\u7d93\u6bd2\u6027\u5291 (Neurotoxic agent) \u4e5f\u5df2\u6210\u529f\u7528\u65bc\u5728\u9ad4\u5916\u5207\u7247\u57f9\u990a\u6a21\u578b\u4e2d\u518d\u73fe\u5e15\u91d1\u68ee\u6a23 (Parkinsons-like) \u7279\u5fb5\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n(2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-][1]benzopyran-6(6aH)-one<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to yellow solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n83-79-4<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2083H\u2082\u2082O\u2086<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n394.42<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226595% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (100 mM) or EtOH (5 mM)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C23H22O6\/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14\/h5-7,9,16,20-21H,1,8,10H2,2-4H3\/t16-,20-,21+\/m1\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nJUVIOZPCNVVQFO-HBGVWJBISA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n6758<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD09025614<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from light and moisture<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n
USAGE<\/strong><\/td>\nFor Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/strong><\/p>\n

 <\/p>\n

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 <\/p>\n","protected":false},"excerpt":{"rendered":"

Rotenone\u6bba\u87f2\u5291 | \u8ca8\u865f2248 A mitochondrial electron transport […]<\/p>\n","protected":false},"author":3,"featured_media":20858,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[2133],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/20857"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20857"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/20857\/revisions"}],"predecessor-version":[{"id":20859,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/20857\/revisions\/20859"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/20858"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20857"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}