{"id":18890,"date":"2019-02-16T10:58:46","date_gmt":"2019-02-16T02:58:46","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18890"},"modified":"2022-07-20T14:36:22","modified_gmt":"2022-07-20T06:36:22","slug":"chlorpromazine%e5%a4%9a%e5%b7%b4%e8%83%ba%e5%8f%97%e9%ab%94%e6%8b%ae%e6%8a%97%e5%8a%91-%e8%b2%a8%e8%99%9fb1992","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=18890","title":{"rendered":"Chlorpromazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1992\u00a0"},"content":{"rendered":"

Chlorpromazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1992\u00a0<\/a><\/span><\/p>\n

A dopamine receptor antagonist<\/p>\n

\"\"<\/p>\n

\u7522\u54c1\u4ecb\u7d39\uff1a Chlorpromazine\u662fdopamine receptor antagonist\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291; \u6e1b\u5c11neurotransmitter binding\u795e\u7d93\u905e\u8cea\u7684\u7d50\u5408\u3002 \u6291\u5236\u5c0f\u9f20\u8166\u7d30\u80de\u6eb6\u8cea\u4e2d\u7684nitric oxide synthesis\u4e00\u6c27\u5316\u6c2e\u5408\u6210\u3002 \u4e5f\u53ef\u4f5c\u70banAChR\uff0c\u7d44\u80fa\u548c5-HT\u53d7\u9ad4\u7684\u62ee\u6297\u5291\u3002 \u986f\u793a\u5c0d\u591a\u7a2e\u816b\u7624\u7d30\u80de\u7cfb\u7684\u751f\u9577\u6291\u5236\u4f5c\u7528\u3002\u8868\u73fe\u51fa\u6297\u7cbe\u795e\u75c5\u6d3b\u52d5\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/td>\n2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, monohydrochloride; CPZ; Thorazine; Promacid<\/td>\n<\/tr>\n
Appearance<\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/td>\n69-09-0<\/td>\n<\/tr>\n
Molecular Formula<\/td>\nC\u2081\u2087H\u2081\u2089ClN\u2082S \u2022 HCl<\/td>\n<\/tr>\n
Molecular Weight<\/td>\n355.32<\/td>\n<\/tr>\n
Purity<\/td>\n\u226598%<\/td>\n<\/tr>\n
Solubility<\/td>\nDMSO (~ 30 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/td>\nN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl<\/td>\n<\/tr>\n
InChi<\/td>\nInChI=1S\/C17H19ClN2S.ClH\/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;\/h3-4,6-9,12H,5,10-11H2,1-2H3;1H<\/td>\n<\/tr>\n
InChi Key<\/td>\nFBSMERQALIEGJT-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/td>\n6240<\/td>\n<\/tr>\n
MDL Number<\/td>\nMFCD00012654<\/td>\n<\/tr>\n
Handling<\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

\"\u76f8\u95dc\u8a66\u5291\"<\/a><\/strong><\/span><\/span>\u00a0Dopamine<\/u>\u591a\u5df4\u80fa\u6aa2\u6e2cK4219\u00a0<\/u>\u00a0<\/a> | \u03b1-<\/u>\u7a81\u89f8\u6838\u86cb\u767d\uff08SNCA<\/u>\uff09ELISA<\/u>\u8a66\u5291\u76d2K4261-100 <\/u>\u00a0<\/a>| \u55ae\u80fa\u6c27\u5316\u9176\u6d3b\u6027\uff08\u7e3dMAO \/ MAO-A \/ MAO-B<\/u>\uff09<\/u>\u6aa2\u6e2c<\/a><\/span>\u00a0| \u00a0Chlorpromazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291<\/a><\/u>\u00a0| Chlorpromazine<\/u>\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291<\/u> <\/a>| GDNF\u591a\u5df4\u80fa\u651d\u53d6<\/a>\u4fc3\u9032\u5291<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Chlorpromazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1992\u00a0 A dopamine receptor a […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[2371],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18890"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18890"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18890\/revisions"}],"predecessor-version":[{"id":18915,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18890\/revisions\/18915"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18890"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18890"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18890"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}