{"id":18886,"date":"2019-02-16T10:47:58","date_gmt":"2019-02-16T02:47:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18886"},"modified":"2022-07-20T14:36:29","modified_gmt":"2022-07-20T06:36:29","slug":"thioridazine%e5%a4%9a%e5%b7%b4%e8%83%ba%e5%8f%97%e9%ab%94%e6%8b%ae%e6%8a%97%e5%8a%91-%e8%b2%a8%e8%99%9fb1581","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=18886","title":{"rendered":"Thioridazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1581\u00a0"},"content":{"rendered":"

Thioridazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1581\u00a0<\/a><\/span><\/p>\n

Thioridazine Hydrochloride<\/p>\n

\"\"<\/p>\n

\u7522\u54c1\u4ecb\u7d39\uff1a Thioridazine\u662f\u4e00\u7a2edopamine receptor antagonist\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291\uff0c\u5177\u6709antipsychotic activity\u6297\u7cbe\u795e\u75c5\u6d3b\u6027\u3002 \u5b83\u6291\u5236\u5e7e\u7a2e\u985e\u578b\u7684\u764c\u75c7\u4e26\u4e14\u5c0dleukemia stem cells\u767d\u8840\u75c5\u5e79\u7d30\u80de\u5177\u6709\u7279\u7570\u6027\u3002 \u9084\u986f\u793a\u51fa\u5c0dlung cancer stem-like cells\u80ba\u764c\u5e79\u7d30\u80de\u6a23\u7d30\u80de\u7684\u6709\u6548\u6297\u816b\u7624\u4f5c\u7528\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/td>\n10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine, hydrochloride; TDZ<\/td>\n<\/tr>\n
Appearance<\/td>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/td>\n130-61-0<\/td>\n<\/tr>\n
Molecular Formula<\/td>\nC\u2082\u2081H\u2082\u2086N\u2082S\u2082.HCl<\/td>\n<\/tr>\n
Molecular Weight<\/td>\n407.04<\/td>\n<\/tr>\n
Purity<\/td>\n\u226598%<\/td>\n<\/tr>\n
Solubility<\/td>\nDMSO (>35 mg\/ml) or H2O (>25 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/td>\nCN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl<\/td>\n<\/tr>\n
InChi<\/td>\nInChI=1S\/C21H26N2S2.ClH\/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;\/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H<\/td>\n<\/tr>\n
InChi Key<\/td>\nNZFNXWQNBYZDAQ-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/td>\n66062<\/td>\n<\/tr>\n
MDL Number<\/td>\nMFCD00012655<\/td>\n<\/tr>\n
Handling<\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u76f8\u95dc\u8a66\u5291\"<\/a><\/strong><\/span><\/span>\u00a0Dopamine<\/u>\u591a\u5df4\u80fa\u6aa2\u6e2cK4219\u00a0<\/u>\u00a0<\/a> | \u03b1-<\/u>\u7a81\u89f8\u6838\u86cb\u767d\uff08SNCA<\/u>\uff09ELISA<\/u>\u8a66\u5291\u76d2K4261-100 <\/u>\u00a0<\/a>| \u55ae\u80fa\u6c27\u5316\u9176\u6d3b\u6027\uff08\u7e3dMAO \/ MAO-A \/ MAO-B<\/u>\uff09<\/u>\u6aa2\u6e2c<\/a><\/span>\u00a0| \u00a0Chlorpromazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291<\/a><\/u>\u00a0| Thioridazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291<\/a><\/span>| GDNF\u591a\u5df4\u80fa\u651d\u53d6<\/a>\u4fc3\u9032\u5291<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Thioridazine\u591a\u5df4\u80fa\u53d7\u9ad4\u62ee\u6297\u5291 | \u8ca8\u865fB1581\u00a0 Thioridazine Hydrochlor […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[2372],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18886"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18886"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18886\/revisions"}],"predecessor-version":[{"id":18916,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18886\/revisions\/18916"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18886"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18886"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18886"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}