{"id":18869,"date":"2019-02-15T11:39:41","date_gmt":"2019-02-15T03:39:41","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18869"},"modified":"2022-07-20T14:37:29","modified_gmt":"2022-07-20T06:37:29","slug":"ezcyp%e6%b4%bb%e6%80%a7%e4%ba%ba%e9%a1%9e%e9%87%8d%e7%b5%84%e7%b4%b0%e8%83%9e%e8%89%b2%e7%b4%a0p450-3a4-%e8%b2%a8%e8%99%9f7872","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=18869","title":{"rendered":"EZCyp\u2122\u6d3b\u6027\u4eba\u985e\u91cd\u7d44\u7d30\u80de\u8272\u7d20P450 3A4 | \u8ca8\u865f7872"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=18869\">EZCyp\u2122\u6d3b\u6027\u4eba\u985e\u91cd\u7d44\u7d30\u80de\u8272\u7d20P450 3A4 <strong>| <\/strong><strong>\u8ca8\u865f<\/strong>7872<\/a><\/span><\/p>\n<p><strong><em>EZCyp\u2122 Active Human Cytochrome P450 3A4-Unique, <\/em><\/strong><em>cost-effective CYP3A4 catalytic system with active recombinant human CYP3A4 coexpressed with the active NADPH reductase in a semipermeable membrane system.<\/em><\/p>\n<p><strong>\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>\u7d30\u80de\u8272\u7d20P450 3A4\uff08Cytochrome P450 3A4, CYP3A4\uff0cEC 1.14.13.157\uff09\u662fmicrosomal xenobiotic metabolism enzymes\u5fae\u7c92\u9ad4\u7570\u751f\u7269\u8cea\u4ee3\u8b1d\u9176\u7684\u7d30\u80de\u8272\u7d20P450\u55ae\u6c27\u5316\u9176\uff08CYP\uff09\u5bb6\u65cf\u7684\u6210\u54e1\u3002 CYP\u662f\u8ca0\u8cacI\u671f\u751f\u7269\u8f49\u5316\u53cd\u61c9\u7684membrane-bound hemeproteins\u819c\u7d50\u5408\u8840\u7d05\u7d20\u86cb\u767d\uff0c\u5176\u4e2d\u89aa\u8102\u6027\u85e5\u7269\u548c\u5176\u4ed6\u7570\u751f\u7269\u8cea\u5316\u5408\u7269\u8f49\u5316\u70ba\u66f4\u89aa\u6c34\u7684\u7522\u7269\u4ee5\u4fc3\u9032\u9ad4\u5167\u6392\u6cc4\u3002 CYP3A4\u5728liver\u809d\u81df\u548cintestines\u8178\u4e2d\u4ee5\u9ad8\u6c34\u5e73\u8868\u9054\uff0c\u5176\u4e2d\u5b83\u50ac\u5316\u6975\u5176\u591a\u7a2e\u7d50\u69cb\u4e0a\u4e0d\u540c\u7684\u914d\u9ad4\u7684\u6c27\u5316\u3002 \u4eba\u985e\u5e38\u7528\u7684\u6240\u6709\u5c0f\u5206\u5b50\u85e5\u7269\u4e2d\u6709\u4e00\u534a\u4ee5\u4e0a\u88abCYP3A4\u4ee3\u8b1d\u3002 BioVision\u7684EZCyp\u21223A4\u662f\u4e00\u7a2e\u900f\u5316\u548c\u7a69\u5b9a\u7684\u9175\u6bcd\u7c89\u672b\u88fd\u5291\uff0c\u542b\u6709\u91cd\u7d44\u4ebaCYP 3A4\u548c\u5728\u76f8\u540c\u88fd\u5291\u4e2d\u8868\u9054\u7684\u91cd\u7d44\u4ebaP450 NADPH\u6c27\u5316\u9084\u539f\u9176\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"https:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/7\/8\/7872_1.jpg\" alt=\"\" width=\"451\" height=\"333\" \/><\/p>\n<table width=\"837\">\n<tbody>\n<tr>\n<td><strong>Alternate Name<\/strong><\/td>\n<td>Cytochrome P450 3A, Cytochrome P450 3A4, Cyt3A4, CYPIIIA, CYPIIIA4, CYP3A, CYP3A4, Microsomal cytochrome P450 3A4, active CYP3A, human cyp3a, human CYP3A4, recombinant human CYP3A4<\/td>\n<\/tr>\n<tr>\n<td><strong>Gene Symbol<\/strong><\/td>\n<td>CYP3A4<\/td>\n<\/tr>\n<tr>\n<td><strong>Gene ID<\/strong><\/td>\n<td>1576<\/td>\n<\/tr>\n<tr>\n<td><strong>Accession #<\/strong><\/td>\n<td>P08684<\/td>\n<\/tr>\n<tr>\n<td><strong>Source<\/strong><\/td>\n<td>Pichia pastoris<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>Dry powder<\/td>\n<\/tr>\n<tr>\n<td><strong>Physical Form Description<\/strong><\/td>\n<td>Lyophilized powder<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Weight<\/strong><\/td>\n<td>55 KDa<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity by<\/strong><\/td>\n<td>NA<\/td>\n<\/tr>\n<tr>\n<td><strong>Endotoxin Level<\/strong><\/td>\n<td>NA<\/td>\n<\/tr>\n<tr>\n<td><strong>Biological Activity<\/strong><\/td>\n<td>NA<\/td>\n<\/tr>\n<tr>\n<td><strong>Reconstitution Instructions<\/strong><\/td>\n<td>100 mM Potassium Phosphate buffer, pH 7.7<\/td>\n<\/tr>\n<tr>\n<td><strong>Handling<\/strong><\/td>\n<td>Centrifuge the vial prior to opening.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>EZCyp\u2122\u6d3b\u6027\u4eba\u985e\u91cd\u7d44\u7d30\u80de\u8272\u7d20P450 3A4 | \u8ca8\u865f7872 EZCyp\u2122 Active Human C [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[2376],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18869"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18869"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18869\/revisions"}],"predecessor-version":[{"id":18870,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18869\/revisions\/18870"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18869"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18869"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}