{"id":18764,"date":"2019-01-25T16:47:49","date_gmt":"2019-01-25T08:47:49","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18764"},"modified":"2022-07-20T14:51:54","modified_gmt":"2022-07-20T06:51:54","slug":"cholesteryl-hemisuccinate-cas-1510-21-0%e8%b2%a8%e8%99%9fb1978-1g","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=18764","title":{"rendered":"Cholesteryl Hemisuccinate | CAS #1510-21-0\u8ca8\u865fB1978-1G"},"content":{"rendered":"

Cholesteryl Hemisuccinate | CAS #1510-21-0\u00a0<\/strong>\u8ca8\u865f<\/strong>B1978-1G<\/a><\/span><\/p>\n

\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>A detergent that stabilizes GPCRs\u3002Cholesteryl hemisuccinate\u81bd\u56fa\u9187\u534a\u7425\u73c0\u9178\u9e7d\u662f\u4e00\u7a2e\u6709\u7528\u7684\u57fa\u65bccholesterol-based detergent\u81bd\u56fa\u9187\u7684\u53bb\u6c61\u5291\uff0c\u53ef\u589e\u52a0G\u86cb\u767d\u5076\u806f\u53d7\u9ad4\uff08GPCR\uff09\u7684\u7a69\u5b9a\u6027\u3002Together with mutagenesis studies and recent GPCR structures, it has been determined that stabilization is attained through a combination of specific sterol binding to GPCRs and modulation of micelle morphology.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n3\u03b2-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3\u03b2-ol 3-hemisuccinate; CHS<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n1510-21-0<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2083\u2081H\u2085\u2080O\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n486.73<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226595%<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nEtOH (warm; with faint turbidity)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)CCC(=O)O)C)C<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C31H50O4\/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5\/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)\/t21-,23+,24+,25-,26+,27+,30+,31-\/m1\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nWLNARFZDISHUGS-MIXBDBMTSA-N<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Cholesteryl Hemisuccinate | CAS #1510-21-0\u00a0\u8ca8\u865fB1978-1G \u7522 […]<\/p>\n","protected":false},"author":3,"featured_media":18765,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[2397],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18764"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18764"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18764\/revisions"}],"predecessor-version":[{"id":18766,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18764\/revisions\/18766"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/18765"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18764"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18764"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18764"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}