{"id":17344,"date":"2018-07-25T16:40:17","date_gmt":"2018-07-25T08:40:17","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=17344"},"modified":"2022-07-20T16:25:03","modified_gmt":"2022-07-20T08:25:03","slug":"%e6%99%9a%e6%9c%9f%e7%b3%96%e5%9f%ba%e5%8c%96%e7%b5%82%e7%94%a2%e7%89%a9%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%943-dg-imidazolone-exalpha%e8%b2%a8%e8%99%9fimi043","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=17344","title":{"rendered":"\u665a\u671f\u7cd6\u57fa\u5316\u7d42\u7522\u7269\u55ae\u682a\u6297\u9ad4|3-DG-Imidazolone exalpha\u8ca8\u865fIMI043"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=17344\"><strong>3-DG-Imidazolone<\/strong><strong>\uff08\u665a\u671f\u7cd6\u57fa\u5316\u7d42\u7522\u7269\uff090.25 mg\/ml<\/strong><strong> | <\/strong><strong>\u8ca8\u865f<\/strong><strong>IMI043<\/strong><\/a><\/span><\/p>\n<p><strong>\u00a0<\/strong>3-DG-derived imidazolone-AGE\u65bc\u8840\u6db2\u900f\u6790\u60a3\u8005\u7684\u814e\u7d44\u7e54\u3001\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u6676\u72c0\u9ad4\u767d\u5167\u969c\u548c\u5916\u5074\u786c\u5316\u60a3\u8005\u7684\u904b\u52d5\u795e\u7d93\u5143\u4e2d\uff0c\u53ef\u4ee5\u6aa2\u6e2c\u52303-DG\u884d\u751f\u7684\u54aa\u5511\u916e-AGE\u8868\u73fe\u3002\u8a723-DG-derived imidazolone-AGE\u6297\u9ad4\u9069\u7528\u65bc\u6162\u6027\u75be\u75c5\u7684\u7814\u7a76\uff0c\u5176\u4e2d3-DG-\u884d\u751f\u7684\u54aa\u5511\u916e-AGE\u7684\u7d2f\u7a4d\u53ef\u80fd\u662f\u81f4\u75c5\u7684\u3002\u86cb\u767d\u8cea\u8207\u8461\u8404\u7cd6\u7684\u9577\u671f\u5b75\u80b2\u901a\u904eSchiff\u9e7c\u548cAmadori\u91cd\u6392\u7522\u7269\u5c0e\u81f4\u5f62\u6210\u665a\u671f\u7cd6\u57fa\u5316\u7d42\u7522\u7269\uff08AGE\uff09\u3002\u6700\u8fd1\u4f7f\u7528\u6297AGE\u6297\u9ad4\u7684\u514d\u75ab\u5b78\u7814\u7a76\u8868\u660e\u5728\uff08i\uff09\u4eba\u6676\u72c0\u9ad4\u4e2d\u5b58\u5728AGE\uff0c\uff08ii\uff09\u60a3\u6709\u7cd6\u5c3f\u75c5\u6027\u814e\u75c5\u548c\u6162\u6027\u814e\u8870\u7aed\u7684\u60a3\u8005\u7684\u814e\u8fd1\u7aef\u5c0f\u7ba1\uff0c\uff08iii\uff09\u52d5\u8108\u58c1\u7684\u52d5\u8108\u7ca5\u6a23\u786c\u5316\u75c5\u8b8a\uff0c\uff08iv\uff09\u00df2-\u8840\u7ba1\u900f\u6790\u76f8\u95dc\u6fb1\u7c89\u6a23\u8b8a\u6027\u60a3\u8005\u548c\uff08v\uff09\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u8166\u7d44\u7e54\u4e2d\u8155\u7ba1\u6fb1\u7c89\u6a23\u86cb\u767d\u539f\u7e96\u7dad\u6c89\u7a4d\u7684\u5fae\u7403\u86cb\u767d\u3002\u901a\u904e3-\u812b\u6c27\u8461\u91a3\u919b\u916e\uff083-DG\uff09\u5f62\u6210AGE\u5b58\u5728\u975e\u6c27\u5316\u9014\u5f91\u3002 3-DG\u662fMaillard reaction\u7f8e\u62c9\u5fb7\u53cd\u61c9\u7684\u4e2d\u9593\u7522\u7269\uff0c\u5176\u901a\u904e\u8207\u86cb\u767d\u8cea\u7684arginin residues\u7cbe\u6c28\u9178\u6b98\u57fa\u53cd\u61c9\u5f62\u6210\u54aa\u5511\u916e\u3002<\/p>\n<p>\u7522\u54c1\u4ecb\u7d39:<strong>3-DG-Imidazolone<\/strong><strong>\u55ae\u682a\u6297\u9ad4<\/strong>3-DG-derived imidazolone-AGE Catalogue, <strong>\u665a\u671f\u7cd6\u57fa\u5316\u7d42\u7522\u7269<\/strong><strong>\u6297\u9ad4<\/strong><strong> (Clone: <\/strong>JNH-27)<strong>\uff0c<\/strong>number:<strong>\u00a0IMI043\u00a0<\/strong><strong>\u3002<\/strong><strong>\u514d\u75ab\u539f<\/strong><strong>Immunogen<\/strong><strong>\u70ba<\/strong>3-DG-derived Imidazolone-HSA\u00a0\u3002\u7d93\u7531Protein G affinity\u7d14\u5316\u8179\u6c34\u3002\u6297\u9ad4\u4fdd\u5b58\u6db2\u70ba50% Block Ace? (Casein-containing solution, Dainippon Co.) and 0.1% ProClin? (Rohm &amp; Haas) as a preservative\u00a0 \u6297\u9ad4\u4f7f\u7528\u6fc3\u5ea6<strong>Working Concentration<\/strong> (liquid conc.) app. 7 \u00b5g\/ml (IHC(C, P)\u3002<strong>\u4e8c\u6297\u5efa\u8b70<\/strong><strong>:<\/strong> We recommend the use of BIOLOGO&#8217;s Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005).<\/p>\n<table width=\"660\">\n<tbody>\n<tr>\n<td width=\"18%\"><strong>ode<\/strong><\/td>\n<td width=\"56%\"><strong>Name<\/strong><\/td>\n<td width=\"25%\"><strong>Clone<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/25ohvitamin-d3-1-alpha-hydroxylase\/\">HYD001<\/a><\/td>\n<td width=\"56%\">25(OH)Vitamin D3-1-alpha-Hydroxylase<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/3-dg-imidazolone-advanced-glycation-end-product\/\">IMI043<\/a><\/td>\n<td width=\"56%\">3-DG-Imidazolone (Advanced Glycation End Product)<\/td>\n<td width=\"25%\">JNH-27<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/acth-corticotrophin\/\">AC100<\/a><\/td>\n<td width=\"56%\">ACTH, Corticotrophin<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/addicsin-mouse-gtrap3-18\/\">ADD001<\/a><\/td>\n<td width=\"56%\">Addicsin, Mouse (-GTRAP3-18)<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/afp-alpha-fetoprotein\/\">AF100<\/a><\/td>\n<td width=\"56%\">AFP, Alpha-Fetoprotein<\/td>\n<td width=\"25%\">A-013-01\/F1-6P2A8-P2B9A9<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/afp-alpha-fetoprotein-2\/\">AF500<\/a><\/td>\n<td width=\"56%\">AFP, Alpha-Fetoprotein<\/td>\n<td width=\"25%\">A-013-01\/F1-6P2A8-P2B9A9<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-1-glucose-modified\/\">AGE1-010<\/a><\/td>\n<td width=\"56%\">AGE-1 Glucose modified<\/td>\n<td width=\"25%\">7C1<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-3-glycolaldehyde-modified\/\">AGE3-010<\/a><\/td>\n<td width=\"56%\">AGE-3 Glycolaldehyde modified<\/td>\n<td width=\"25%\">9D8<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-4-methylglyoxal-modifiied\/\">AGE4-010<\/a><\/td>\n<td width=\"56%\">AGE-4 Methylglyoxal modifiied<\/td>\n<td width=\"25%\">14B5<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-products\/\">AGE101-0.2<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-products-2\/\">AGE102-0.2<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-products-3\/\">AGE102-1.0<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products<\/td>\n<td width=\"25%\"><\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-products-4\/\">AGE612<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products<\/td>\n<td width=\"25%\">6D12<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-products-hrpo\/\">AGE612HRP<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products: HRPO<\/td>\n<td width=\"25%\">6D12<\/td>\n<\/tr>\n<tr>\n<td width=\"18%\"><a href=\"https:\/\/www.exalpha.com\/product\/age-advanced-glycation-end-productsbio\/\">AGE612BIO<\/a><\/td>\n<td width=\"56%\">AGE, Advanced Glycation End Products:BIO<\/td>\n<td width=\"25%\">6D12<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong><br \/>\n<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-DG-Imidazolone\uff08\u665a\u671f\u7cd6\u57fa\u5316\u7d42\u7522\u7269\uff090.25 mg\/ml | \u8ca8\u865fIMI043 \u00a03-DG-d [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":17345,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[459],"tags":[2640],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17344"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17344"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17344\/revisions"}],"predecessor-version":[{"id":17346,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17344\/revisions\/17346"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/17345"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17344"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17344"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17344"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}