{"id":15622,"date":"2018-02-08T14:34:23","date_gmt":"2018-02-08T06:34:23","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=15622"},"modified":"2022-07-20T17:45:03","modified_gmt":"2022-07-20T09:45:03","slug":"%e7%b3%96%e5%8e%9f%e5%90%88%e6%88%90%e9%85%b6%e6%bf%80%e9%85%b6-3%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%94-mouse-anti-gsk-3%ce%b1-hrp-southernbiotech-%e8%b2%a8%e8%99%9f10910-05","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=15622","title":{"rendered":"\u7cd6\u539f\u5408\u6210\u9176\u6fc0\u9176-3\u55ae\u682a\u6297\u9ad4 | Mouse Anti-GSK-3\u03b1-HRP Southernbiotech \u8ca8\u865f10910-05"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=15622\">Mouse Anti-GSK-3\u03b1-HRP<strong> | <\/strong><strong>\u8ca8\u865f<\/strong><strong>10910-05 \u00a0\u00a0<\/strong><strong>\u898f\u683c<\/strong>1.0 mL<\/a><\/span><\/p>\n<p><strong>\u7522\u54c1\u4ecb\u7d39<\/strong><strong>:<\/strong> \u7cd6\u539f\u5408\u6210\u9176\u6fc0\u9176-3\uff08GSK-3\uff09\u662f\u78f7\u9178\u5316\u7cd6\u539f\u5408\u9176\u5f9e\u800c\u4f7f\u5176\u5931\u6d3b\u7684\u86cb\u767d\u8cea\u7d72\u6c28\u9178\u6fc0\u9176\u3002 \u80f0\u5cf6\u7d20\u523a\u6fc0GSK-3\u78f7\u9178\u5316\u4f4d\u9ede\u7684\u7cd6\u539f\u5408\u9176\u7684\u53bb\u78f7\u9178\u5316\uff0c\u4e26\u96a8\u5f8c\u56b4\u91cd\u6291\u5236GSK-3\u5c0e\u81f4\u7cd6\u539f\u5408\u6210\u7684\u523a\u6fc0\u3002 GSK-3\u4fe1\u865f\u901a\u904e\u5169\u7a2e\u540c\u5de5\u578b\uff0cGSK-3\u03b1\u548cGSK-3\u03b2\u9032\u884c\u3002 \u5169\u7a2e\u540c\u7a2e\u578b\u5728\u5b83\u5011\u7684\u50ac\u5316\u7d50\u69cb\u57df\u5167\u5177\u670997\uff05\u7684\u5e8f\u5217\u76f8\u4f3c\u6027\u3002 GSK-3\u4e5f\u88ab\u8b49\u660e\u5728\u86cb\u767d\u8cea\u5408\u6210\uff0c\u7d30\u80de\u7c98\u9644\uff0c\u7d30\u80de\u589e\u6b96\uff0c\u7d30\u80de\u5206\u5316\uff0c\u5fae\u7ba1\u52d5\u529b\u5b78\u548c\u7d30\u80de\u904b\u52d5\u4e2d\u8d77\u4f5c\u7528\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.southernbiotech.com\/ImageUtil.aspx?img=\/ProductImages2\/10910-05.01.jpg&amp;op=sb&amp;h=275&amp;w=210\" alt=\"Mouse Anti-GSK-3a-HRP\" \/><\/p>\n<p>Lane 1 &#8211; Jurkat<br \/>\nLane 2 &#8211; NIH 3T3<br \/>\nTotal cell lysates were resolved by electrophoresis, transferred to PVDF membrane, and probed with Mouse Anti-GSK-3\u03b1-HRP (SB Cat. No. 10910-05). Proteins were visualized using chemiluminescent detection.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Clone<\/strong><\/td>\n<td>SBGSK3\u03b14<\/td>\n<\/tr>\n<tr>\n<td><strong>Isotype<\/strong><\/td>\n<td>Mouse (BALB\/c) IgG<sub>2a<\/sub>\u03ba<\/td>\n<\/tr>\n<tr>\n<td><strong>Isotype Control<\/strong><\/td>\n<td><a href=\"https:\/\/www.southernbiotech.com\/?catno=0103-05&amp;type=Monoclonal\">Mouse IgG<sub>2a<\/sub>-HRP<\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>Immunogen<\/strong><\/td>\n<td>Recombinant N-terminal GSK-3\u03b1<\/td>\n<\/tr>\n<tr>\n<td><strong>Specificity<\/strong><\/td>\n<td>Human\/Mouse GSK-3\u03b1<\/td>\n<\/tr>\n<tr>\n<td><strong>Alternalte Name(s)<\/strong><\/td>\n<td>Glycogen synthase kinase-3 alpha<\/td>\n<\/tr>\n<tr>\n<td><strong>Description<\/strong><\/td>\n<td>Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3\u03b1 and GSK-3\u03b2. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics, and cell motility.<\/td>\n<\/tr>\n<tr>\n<td><strong>Format\/Conjugate<\/strong><\/td>\n<td>HRP (Horseradish Peroxidase)<\/td>\n<\/tr>\n<tr>\n<td><strong>Buffer Formulation<\/strong><\/td>\n<td>Supplied in a stock solution of 50% glycerol\/50% PBS, pH 7.4; No preservative added<\/td>\n<\/tr>\n<tr>\n<td><strong>Volume<\/strong><\/td>\n<td>1.0 mL<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage &amp; Handling<\/strong><\/td>\n<td>Store at 2-8\u00b0C<br \/>\nPlease refer to product specific\u00a0<a href=\"https:\/\/www.southernbiotech.com\/Msds\/10910-05.pdf\">SDS<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mouse Anti-GSK-3\u03b1-HRP | \u8ca8\u865f10910-05 \u00a0\u00a0\u898f\u683c1.0 mL \u7522\u54c1\u4ecb\u7d39: \u7cd6\u539f\u5408 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":15623,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[2912],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15622"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15622"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15622\/revisions"}],"predecessor-version":[{"id":15624,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15622\/revisions\/15624"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/15623"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15622"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15622"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15622"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}