{"id":14837,"date":"2017-10-19T16:10:07","date_gmt":"2017-10-19T08:10:07","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=14837"},"modified":"2022-07-21T10:15:19","modified_gmt":"2022-07-21T02:15:19","slug":"milrinone-camp-specific%ef%bc%88pdeiii%ef%bc%89%e6%8a%91%e5%88%b6%e5%8a%91-cas-78415-72-2%e8%b2%a8%e8%99%9f2163","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=14837","title":{"rendered":"Milrinone | cAMP-specific\uff08PDEIII\uff09\u6291\u5236\u5291 CAS# 78415-72-2\u8ca8\u865f2163"},"content":{"rendered":"

Milrinone <\/strong>\u00a0| \u00a0CAS#<\/strong> 78415-72-2\u8ca8\u865f<\/strong>2163<\/a><\/span><\/p>\n

A cAMP-specific phosphodiesterase (PDEIII ) inhibitor<\/em><\/strong><\/p>\n

\u7522\u54c1<\/strong>\u63cf\u8ff0\uff1a<\/strong>\u7d30\u80de\u6ef2\u900f\u6027\u3002 \u4e00\u7a2e\u6709\u6548\u7684cAMP\u7279\u7570\u6027\u78f7\u9178\u4e8c\u916f\u9176\uff08PDEIII\uff09\u6291\u5236\u5291\uff08\u5206\u5225\u70baIC 50 = 0.45\u548c1.0\u03bcM\uff0c\u5206\u5225\u70baPDEIIIA\u548cPDEIIIB\uff09\u3002 \u5b83\u4ee5\u66f4\u9ad8\u7684\u6fc3\u5ea6\u6291\u5236\u5176\u4ed6PDE\u540c\u7a2e\u578b\u3002 \u7576\u5728\u9ad4\u5167\u65bd\u7528\u6642\uff0cMilrinone\u5177\u6709\u6b63\u6027\u808c\u529b\u6536\u7e2e\uff08\u523a\u6fc0\u5fc3\u808c\u6536\u7e2e\uff09\u548c\u8840\u7ba1\u64f4\u5f35\u4f5c\u7528\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n1,\u200b6-\u200bdihydro-\u200b2-\u200bmethyl-\u200b6-\u200boxo-\u200b[3,\u200b4′-\u200bbipyridine]-\u200b5-\u200bcarbonitrile; WIN 47, 203<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nOff-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n78415-72-2<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2082H\u2089N\u2083O<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n211.22<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598%<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (10 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C12H9N3O\/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8\/h2-6H,1H3,(H,15,16)<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nPZRHRDRVRGEVNW-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n4197<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00133539<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u76f8\u95dc\u8a66\u5291\"<\/span><\/a>\u00a0<\/a>PDE\u7e3d\u78f7\u9178\u4e8c\u916f\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a>|\u00a0\u00a0<\/strong>Apremilast<\/a>\u00a0 |\u00a0Roflumilast<\/a>\u00a0|\u00a0Zaprinast<\/a>\u00a0|\u00a0IBMX<\/a>\u00a0|\u00a0Cilostazol\u00a0<\/a>\u00a0|\u00a0Milrinone<\/a>\u00a0|\u00a0<\/strong><\/span><\/strong><\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Milrinone \u00a0| \u00a0CAS# 78415-72-2\u8ca8\u865f2163 A cAMP-specific pho […]<\/p>\n","protected":false},"author":3,"featured_media":14839,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[3084],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14837"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14837"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14837\/revisions"}],"predecessor-version":[{"id":14869,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14837\/revisions\/14869"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/14839"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14837"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14837"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}