{"id":14833,"date":"2017-10-19T15:54:53","date_gmt":"2017-10-19T07:54:53","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=14833"},"modified":"2022-07-21T10:15:25","modified_gmt":"2022-07-21T02:15:25","slug":"cilostazol-pde3-%e6%8a%91%e5%88%b6%e5%8a%91-cas73963-72-1%e8%b2%a8%e8%99%9f2393","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=14833","title":{"rendered":"Cilostazol (PDE3) \u6291\u5236\u5291 | CAS#73963-72-1\u8ca8\u865f2393"},"content":{"rendered":"

Cilostazol <\/strong>\u00a0| \u00a0CAS#<\/strong>73963-72-1\u8ca8\u865f<\/strong>2393<\/a><\/span><\/p>\n

A phosphodiesterase 3 (PDE3) inhibitor<\/em><\/strong><\/p>\n

\u7522\u54c1<\/strong>\u63cf\u8ff0\uff1aCilostazol<\/strong>\u897f\u6d1b\u4ed6\u5511\u662f\u81e8\u5e8a\u6279\u51c6\u7684\u78f7\u9178\u4e8c\u916f\u9176III\uff08PDE3\uff09\u6291\u5236\u5291\uff08IC 50 =0.2\u03bcM\uff09\u548c\u6297\u8840\u6813\u5f62\u6210\u5291\u3002 \u5b83\u6291\u5236\u8840\u5c0f\u677f\u805a\u96c6\u4e26\u4e14\u662f\u76f4\u63a5\u7684\u52d5\u8108\u8840\u7ba1\u64f4\u5f35\u5291\u3002<\/p>\n

\"73963-72-1\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n73963-72-1<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2080H\u2082\u2087N\u2085O\u2082<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n369.46<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598% by TLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (~20 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nC1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C20H27N5O2\/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16\/h10-11,14,16H,1-9,12-13H2,(H,21,26)<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nRRGUKTPIGVIEKM-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n2754<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u76f8\u95dc\u8a66\u5291\"<\/span><\/a>\u00a0<\/a>PDE\u7e3d\u78f7\u9178\u4e8c\u916f\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a>|\u00a0\u00a0<\/strong>Apremilast<\/a>\u00a0 |\u00a0Roflumilast<\/a>\u00a0|\u00a0Zaprinast<\/a>\u00a0|\u00a0IBMX<\/a>\u00a0|\u00a0Cilostazol\u00a0<\/a>\u00a0|\u00a0Milrinone<\/a>\u00a0|\u00a0<\/strong><\/span><\/strong><\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Cilostazol \u00a0| \u00a0CAS#73963-72-1\u8ca8\u865f2393 A phosphodiesterase […]<\/p>\n","protected":false},"author":3,"featured_media":14834,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[3085],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14833"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14833"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14833\/revisions"}],"predecessor-version":[{"id":14875,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14833\/revisions\/14875"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/14834"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14833"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14833"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}