{"id":14826,"date":"2017-10-19T15:30:56","date_gmt":"2017-10-19T07:30:56","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=14826"},"modified":"2022-07-21T10:15:39","modified_gmt":"2022-07-21T02:15:39","slug":"zaprinast%ef%bc%88pde-v-inhibitor%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%89-cas37762-06-4%e8%b2%a8%e8%99%9f1715","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=14826","title":{"rendered":"Zaprinast\uff08PDE V inhibitor\u6291\u5236\u5291\uff09 | CAS37762-06-4\u8ca8\u865f1715"},"content":{"rendered":"

Zaprinast<\/strong>\uff08<\/strong>PDE V inhibitor<\/em><\/strong>\u6291\u5236\u5291<\/strong>\uff09<\/strong> | \u00a0CAS<\/strong>37762-06-4\u8ca8\u865f<\/strong>1715<\/a><\/span><\/p>\n

A PDE V inhibitor<\/em><\/strong><\/p>\n

\"\"<\/p>\n

\u7522\u54c1<\/strong>\u63cf\u8ff0\uff1a<\/strong>\u7d30\u80de\u6ef2\u900f\u6027\u3002 cGMP\u7279\u7570\u6027\u78f7\u9178\u4e8c\u916f\u9176\uff08PDE V\uff09\u7684\u9078\u64c7\u6027\u6291\u88fd\u5291\uff08IC 50 =0.45\u03bcM\uff09\u3002 \u50c5\u5728\u8f03\u9ad8\u6fc3\u5ea6\uff08IC 50 =35\u03bcM\uff09\u4e0b\u6291\u5236PDE IX\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Cat # +Size<\/strong><\/td>\n1715-25<\/td>\n<\/tr>\n
Size<\/strong><\/td>\n25 mg<\/td>\n<\/tr>\n
Alternate Name<\/strong><\/td>\n1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one; M&B 22948<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n37762-06-4<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2083H\u2081\u2083N\u2085O\u2082<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n271.27<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (100 mM)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCCCOC1=CC=CC=C1C2=NC(=O)C3=NNNC3=N2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u76f8\u95dc\u8a66\u5291\"<\/span><\/a>\u00a0<\/a>PDE\u7e3d\u78f7\u9178\u4e8c\u916f\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a>|\u00a0\u00a0<\/strong>Apremilast<\/a>\u00a0 |\u00a0Roflumilast<\/a>\u00a0|\u00a0Zaprinast<\/a>\u00a0|\u00a0IBMX<\/a>\u00a0|\u00a0Cilostazol\u00a0<\/a>\u00a0|\u00a0Milrinone<\/a>\u00a0|\u00a0<\/strong><\/span><\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Zaprinast\uff08PDE V inhibitor\u6291\u5236\u5291\uff09 | \u00a0CAS37762-06-4\u8ca8\u865f1715 A […]<\/p>\n","protected":false},"author":3,"featured_media":14827,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[3087],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14826"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14826"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14826\/revisions"}],"predecessor-version":[{"id":14870,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14826\/revisions\/14870"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/14827"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14826"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}