{"id":14822,"date":"2017-10-19T15:08:26","date_gmt":"2017-10-19T07:08:26","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=14822"},"modified":"2022-07-21T10:15:45","modified_gmt":"2022-07-21T02:15:45","slug":"roflumilast%e9%81%b8%e6%93%87%e6%80%a7%e7%a3%b7%e9%85%b8%e4%ba%8c%e9%85%af%e9%85%b64%ef%bc%88pde4%ef%bc%89%e6%8a%91%e5%88%b6%e5%8a%91-cas162401-32-3%e8%b2%a8%e8%99%9f2675","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=14822","title":{"rendered":"Roflumilast\u9078\u64c7\u6027\u78f7\u9178\u4e8c\u916f\u91764\uff08PDE4\uff09\u6291\u5236\u5291 | CAS162401-32-3\u8ca8\u865f2675"},"content":{"rendered":"

Roflumilast<\/strong>\uff08<\/strong>\u9078\u64c7\u6027\u78f7\u9178\u4e8c\u916f\u9176<\/strong>4<\/strong>\uff08<\/strong>PDE4<\/strong>\uff09\u6291\u5236\u5291<\/strong>\uff09<\/strong> | \u00a0CAS<\/strong>162401-32-3\u8ca8\u865f<\/strong>2675<\/a><\/span><\/p>\n

Highly Sensitive, minimal sample preparation required<\/p>\n

\u7522\u54c1<\/strong>\u63cf\u8ff0\uff1aRoflumilast<\/strong>\u7f85\u6c1f\u53f8\u7279\u662f\u9078\u64c7\u6027\u78f7\u9178\u4e8c\u916f\u91764\uff08PDE4\uff09\u6291\u5236\u5291\uff08IC 50 = 0.8nM\uff09\u3002 \u626e\u6f14\u6297\u708e\u7279\u6027\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\n3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107; BY 217; BYK 20869; Daxas<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n162401-32-3<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2087H\u2081\u2084Cl\u2082F\u2082N\u2082O\u2083<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n403.21<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226598% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (>20 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nC1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n


\n\"\u76f8\u95dc\u8a66\u5291\"<\/span><\/a>\u00a0<\/a>PDE\u7e3d\u78f7\u9178\u4e8c\u916f\u9176\u6d3b\u6027\u6e2c\u5b9a<\/a>|\u00a0\u00a0<\/strong>Apremilast<\/a>\u00a0 |\u00a0Roflumilast<\/a>\u00a0|\u00a0Zaprinast<\/a>\u00a0|\u00a0IBMX<\/a>\u00a0|\u00a0Cilostazol\u00a0<\/a>\u00a0|\u00a0Milrinone<\/a>\u00a0|\u00a0<\/strong><\/span><\/strong><\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Roflumilast\uff08\u9078\u64c7\u6027\u78f7\u9178\u4e8c\u916f\u91764\uff08PDE4\uff09\u6291\u5236\u5291\uff09 | \u00a0CAS162401-32-3\u8ca8\u865f2675 […]<\/p>\n","protected":false},"author":3,"featured_media":14823,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[3088],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14822"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14822"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14822\/revisions"}],"predecessor-version":[{"id":14874,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/14822\/revisions\/14874"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/14823"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14822"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14822"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}