{"id":12918,"date":"2017-08-18T12:06:27","date_gmt":"2017-08-18T04:06:27","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=12918"},"modified":"2022-07-21T11:22:47","modified_gmt":"2022-07-21T03:22:47","slug":"trastuzumab%e6%9b%b2%e5%a6%a5%e7%8f%a0%e5%96%ae%e6%8a%97%e9%87%8d%e7%b5%84%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%94-anti-trastuzumab-anti-idiotype-%e8%b2%a8%e8%99%9fab00619-1-1","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=12918","title":{"rendered":"Trastuzumab\u66f2\u59a5\u73e0\u55ae\u6297\u91cd\u7d44\u55ae\u682a\u6297\u9ad4 | Anti-trastuzumab (anti-idiotype) \u8ca8\u865fAb00619-1-1"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=12918\" target=\"_blank\">Anti-trastuzumab Anti-trastuzumab (anti-idiotype) \u66f2\u59a5\u73e0\u55ae\u6297\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\uff08[scFv40]<\/a><\/span><\/p>\n<p>\u7522\u54c1\u4ecb\u7d39: Trastuzumab\u66f2\u59a5\u73e0\u55ae\u6297\/ human HER2 mimetic\u91cd\u7d44\u55ae\u682a\u6297\u9ad4\uff08anti-idiotype, Clone Number: scFv40\uff09| \u8ca8\u865fAb00619-1-1\u3002 \u4f7f\u7528\u4f86\u81eascFv scFv40\u7684\u53ef\u8b8a\u5340\uff08\u5373\u7279\u7570\u6027\uff09\u3002\u4f7f\u7528\u539f\u59cb\u4ebascFv\u5f62\u5f0f\u7684\u53ef\u8b8a\u7d50\u69cb\u57df\u5e8f\u5217\u88fd\u5099\u8a72\u5d4c\u5408\u9f20\u6297\u9ad4\uff0c\u4ee5\u6539\u5584\u8207\u73fe\u6709\u8a66\u5291\u7684\u76f8\u5bb9\u6027\uff0c\u6e2c\u5b9a\u548c\u6280\u8853\u3002\u6297\u9ad4<strong>\u5206\u578b<\/strong><strong>:<\/strong><strong> \u00a0<\/strong>Mouse IgG1, \u61c9\u7528\u70baBlock; immunogen \u3002\u53cd\u61c9\u7269\u7a2e\u70baHuman\u3002\u514d\u75ab\u539f\u70ba\u00a0Trastuzumab F(ab&#8217;)2 fragments\u3002\u6297\u9ad4\u4e4b\u7279\u7570\u6027\u8fa8\u8996idiotype of trastuzumab, mimicking HER2 epitopes\u3002\u8a72\u6297\u9ad4\u7d50\u5408\u66f2\u59a5\u73e0\u55ae\u6297m2 HER2\u8868\u4f4d\u7684\u7368\u7279\u578b\u3002\u5728\u9f20\u9ad4\u5167\u6a21\u578b\u4e2d\uff0c\u8a72\u6297\u9ad4\u80fd\u5920\u5c07\u6297HER2\u6297\u9ad4\u8207HER2\u967d\u6027\u7684SK-OV-3\u816b\u7624\u7d30\u80de\u9032\u884c\u7f3a\u640d\u3002<\/p>\n<p><strong>Absoluted antibody<\/strong><strong>\u7522\u54c1\u4ecb\u7d39<\/strong><\/p>\n<p>Absoluted Antibody \u63d0\u4f9b\u4e00\u7cfb\u5217\u6297\u9ad4\u5546\u54c1\uff0c\u5176\u4e2dFc Silent\u2122 Antibodies\u7cfb\u5217\uff1b\u80fd\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027Fc\u7d50\u5408\u3002Fc Silent\u2122\u6280\u8853\uff0c\u70ba\u61c9\u7528\u751f\u7269\u5de5\u7a0b\u6280\u8853\uff0c\u5c07Fc receptors (Fc\u03b3R, FcR)\u9ede\u7a81\u8b8a\uff0c\u9032\u800c\u4e2d\u6b62\u6297\u9ad4\u8207ADCC\u7684\u529f\u80fd\uff1b\u6709\u6548\u964d\u4f4eFc\u6240\u9020\u6210\u7684\u80cc\u666f\u8a0a\u865f\u3002Fc Silent\u2122\u6297\u9ad4\u61c9\u7528\u65bc\u514d\u75ab\u7d30\u80de\u6642flow cytometry\u3001immunohistochemistry (IHC)\u8cc7\u6599\u986f\u793a\uff0c\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027\u4e4bFc\u7d50\u5408\uff0c\u6240\u9020\u6210\u7684\u80cc\u666f\u503c\u3002(\u8a02\u8cfc\u6297\u9ad4\u524d\uff0c\u8acb\u78ba\u8a8d\u9078\u64c7\u6297\u9ad4\u662f\u5426\u6709Fc Silent\u2122\u4fee\u98fe\u6a19\u8a8c)\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anti-trastuzumab Anti-trastuzumab (anti-idiotype) \u66f2\u59a5\u73e0\u55ae\u6297 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":2428,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[459],"tags":[3340],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/12918"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=12918"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/12918\/revisions"}],"predecessor-version":[{"id":12921,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/12918\/revisions\/12921"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/2428"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=12918"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=12918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}