GFAP膠質纖維酸性蛋白 | Glial Fibrillary Acidic Protein貨號P1364-10

代理廠牌: | ![]() |
原廠連結: | |
相關下載: |
特點
A class-III intermediate filament that distinguishes astrocytes from other glial cells during the development of the central nervous system
產品介紹: 膠質纖維酸性蛋白(Glial Fibrillary Acidic Protein , GFAP)是一種中間絲(intermediate filament , IF)蛋白,屬於中間絲家族(intermediate filament family)。 GFAP在中樞神經系統(CNS),室管膜細胞(ependymal cells)的許多細胞類型中表達,並由PKN1磷酸化。 GFAP是一種III類中間細絲(class-III intermediate filament),是中樞神經系統發育過程中的一種細胞特異性標誌物(cell-specific marker),可將星形膠質細胞(astrocytes)與其他神經膠質細胞(glial cells)區分開。它與其非上皮家族成員(non-epithelial family members)波形蛋白(vimentin),結蛋白(desmin)和外周蛋白(peripherin)密切相關,它們均參與細胞骨架(cytoskeleton)的結構(structure)和功能(function)。 GFAP被認為有助於維持星形膠質細胞(astrocyte)的機械強度(mechanical strength)以及細胞的形狀(shape),但其確切功能仍知之甚少。
Cat # +Size | P1364-10 |
Size | 10 µg |
Alternate Name | Glial Fibrillary Acidic Protein, GFAP |
Gene Symbol | GFAP |
Gene ID | 2670 |
Accession # | P14136 |
Source | E.coli |
Appearance | Lyophilized |
Physical Form Description | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.25. |